Search Results - "Carter, D E"
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Monomethylarsonous Acid (MMAIII) Is More Toxic Than Arsenite in Chang Human Hepatocytes
Published in Toxicology and applied pharmacology (01-03-2000)“…Methylation has been considered to be the primary detoxication pathway of inorganic arsenic. Inorganic arsenic is methylated by many, but not all animal…”
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2
Surveillance system integration: reporting the results of a global multicountry survey
Published in Public health (London) (01-06-2024)“…Currently, there is no comprehensive picture of the global surveillance landscape. This survey examines the current state of surveillance systems, levels of…”
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3
Toxicity and metabolism of subcytotoxic inorganic arsenic in human renal proximal tubule epithelial cells (HK-2)
Published in Cell biology and toxicology (01-08-2003)“…Arsenic is an environmental toxicant and a human carcinogen. The kidney, a known target organ of arsenic toxicity, is critical for both in vivo arsenic…”
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4
VEGF and angiogenesis in acute and chronic MOG(35–55) peptide induced EAE
Published in Journal of neuroimmunology (30-04-2009)“…Abstract An increased expression of vascular endothelial growth factor (VEGF) is associated with demyelinated lesions in both multiple sclerosis (MS) and its…”
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5
Reactions of arsenic(III) and arsenic(V) species with glutathione
Published in Chemical research in toxicology (01-01-1993)“…Arsenic is metabolized by living systems using oxidation-reduction and methylation reactions, and reduced glutathione (GSH) has been shown to be important in…”
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6
Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana
Published in Science (American Association for the Advancement of Science) (01-08-2003)“…Over 225,000 independent Agrobacterium transferred DNA (T-DNA) insertion events in the genome of the reference plant Arabidopsis thaliana have been created…”
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7
ARSENATE TOXICITY IN HUMAN ERYTHROCYTES: CHARACTERIZATION OF MORPHOLOGIC CHANGES AND DETERMINATION OF THE MECHANISM OF DAMAGE
Published in Journal of Toxicology and Environmental Health, Part A (13-03-1998)“…Chronic arsenic exposure is associated with alterations in peripheral circulation and vascular disease. Toxicity to the vasculature is documented, but the…”
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8
The effects of sulfur, thiol, and thiol inhibitor compounds on arsine-induced toxicity in the human erythrocyte membrane
Published in Toxicological sciences (01-06-2000)“…The mechanism of arsine (AsH(3)) toxicity is not completely understood. The first cytotoxic effect of AsH(3) is disruption of ion homeostasis, with a…”
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9
E2 interference effects in the 12C(α,γ0)16O reaction
Published in Physical review letters (05-10-2012)“…The E1-E2 interference sign between the E(c.m.)=2.68-MeV E2 resonance and an underlying E1 strength has been measured for the first time. An E1-E2 asymmetry…”
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10
In vitro tissue specificity for arsine and arsenite toxicity in the rat
Published in Toxicological sciences (01-11-1999)“…The mechanism of arsine (AsH3) toxicity is not completely understood. In this investigation, we determined AsH3 and arsenite (AsIII) toxicity in Sprague Dawley…”
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11
GLUTATHIONE, ALBUMIN, CYSTEINE, AND CYS-GLY EFFECTS ON TOXICITY AND ACCUMULATION OF MERCURIC CHLORIDE IN LLC-PK1 CELLS
Published in Journal of Toxicology and Environmental Health, Part A (13-08-1999)“…Speciation plays a profound if not dominant role in both transport and toxicity of Hg(II). Hg(II) has a high affinity for sulfhydryl groups. The formation…”
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12
Determination and metabolism of dithiol chelating agents. XII. Metabolism and pharmacokinetics of sodium 2,3-dimercaptopropane-1-sulfonate in humans
Published in The Journal of pharmacology and experimental therapeutics (01-11-1991)“…The sodium salt of 2,3-dimercaptopropane-1-sulfonic acid (DMPS) is used p.o. for the treatment of chronic lead and Hg intoxication in humans. The metabolism…”
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13
SYSTEMIC INDICATORS OF INORGANIC ARSENIC TOXICITY IN FOUR ANIMAL SPECIES
Published in Journal of Toxicology and Environmental Health, Part A (28-01-2000)“…The effect of arsenic compounds depends on the chemical form and is specific for certain organs. The lack of specific biological indicators for the effects of…”
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14
Structural Alterations in the Rat Kidney After Acute Arsine Exposure
Published in Laboratory investigation (01-01-2000)“…The mechanism of arsine (AsH3) toxicity is not completely understood. In this investigation, the toxicity of AsH3 and AsH3-produced hemolytic products was…”
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15
Inorganic mercury chloride-induced apoptosis in the cultured porcine renal cell line LLC-PK1
Published in The Journal of pharmacology and experimental therapeutics (01-06-1996)“…HgCl2 is known to be a renal toxin, but its mechanisms of toxicity are not well understood. The cell line LLC-PK1 was used as a model for renal proximal tubule…”
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16
Determination and metabolism of dithiol chelating agents: X. In humans, meso-2,3-dimercaptosuccinic acid is bound to plasma proteins via mixed disulfide formation
Published in The Journal of pharmacology and experimental therapeutics (01-08-1990)“…meso-2,3-Dimercaptosuccinic acid (DMSA) is orally effective for the treatment of chronic lead intoxication in humans. Earlier studies have shown that the…”
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17
Effects of acute and chronic arsenic exposure of human-derived keratinocytes in an In Vitro human skin equivalent system: a novel model of human arsenicism
Published in Toxicology in vitro (01-02-1997)“…An organotypic culture (OTC) of a human keratinocyte cell line (HaCaT) over a human fibroblast-embedded collagen gel was used to model human epidermis in…”
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18
Comparative pulmonary toxicity of gallium arsenide, gallium(III) oxide, or arsenic(III) oxide intratracheally instilled into rats
Published in Toxicology and applied pharmacology (15-03-1986)“…The relative toxicity of gallium arsenide (GaAs) and its metal oxides was assessed by intratracheally instilling particulate suspensions of GaAs (100 mg/kg),…”
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19
Interactions of rat red blood cell sulfhydryls with arsenate and arsenite
Published in Journal of toxicology and environmental health (01-11-1995)“…Arsenic-thiol interactions were investigated by determining changes in rat blood sulfhydryls after exposure to arsenate, As(V), or arsenite, As(III)…”
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20
Oxidation-Reduction Reactions of Metal Ions
Published in Environmental health perspectives (01-02-1995)“…Several metal or metalloid ions exist in multiple oxidation states and can undergo electron transfer reactions that are important in biological and…”
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