Search Results - "Carter, D E"

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  1. 1

    Monomethylarsonous Acid (MMAIII) Is More Toxic Than Arsenite in Chang Human Hepatocytes by Petrick, Jay S., Ayala-Fierro, Felix, Cullen, William R., Carter, Dean E., Vasken Aposhian, H.

    Published in Toxicology and applied pharmacology (01-03-2000)
    “…Methylation has been considered to be the primary detoxication pathway of inorganic arsenic. Inorganic arsenic is methylated by many, but not all animal…”
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  2. 2

    Surveillance system integration: reporting the results of a global multicountry survey by Carter, E.D., Stewart, D.E., Rees, E.E., Bezuidenhoudt, J.E., Ng, V., Lynes, S., Desenclos, J.C., Pyone, T., Lee, A.C.K.

    Published in Public health (London) (01-06-2024)
    “…Currently, there is no comprehensive picture of the global surveillance landscape. This survey examines the current state of surveillance systems, levels of…”
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  3. 3

    Toxicity and metabolism of subcytotoxic inorganic arsenic in human renal proximal tubule epithelial cells (HK-2) by PERAZA, M. A, CARTER, D. E, GANDOLFI, A. J

    Published in Cell biology and toxicology (01-08-2003)
    “…Arsenic is an environmental toxicant and a human carcinogen. The kidney, a known target organ of arsenic toxicity, is critical for both in vivo arsenic…”
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  4. 4

    VEGF and angiogenesis in acute and chronic MOG(35–55) peptide induced EAE by Roscoe, W.A, Welsh, M.E, Carter, D.E, Karlik, S.J

    Published in Journal of neuroimmunology (30-04-2009)
    “…Abstract An increased expression of vascular endothelial growth factor (VEGF) is associated with demyelinated lesions in both multiple sclerosis (MS) and its…”
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  5. 5

    Reactions of arsenic(III) and arsenic(V) species with glutathione by Scott, Nelson, Hatlelid, Kristina M, MacKenzie, Neil E, Carter, Dean E

    Published in Chemical research in toxicology (01-01-1993)
    “…Arsenic is metabolized by living systems using oxidation-reduction and methylation reactions, and reduced glutathione (GSH) has been shown to be important in…”
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    ARSENATE TOXICITY IN HUMAN ERYTHROCYTES: CHARACTERIZATION OF MORPHOLOGIC CHANGES AND DETERMINATION OF THE MECHANISM OF DAMAGE by Winski, S L, Carter, D E

    “…Chronic arsenic exposure is associated with alterations in peripheral circulation and vascular disease. Toxicity to the vasculature is documented, but the…”
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  8. 8

    The effects of sulfur, thiol, and thiol inhibitor compounds on arsine-induced toxicity in the human erythrocyte membrane by RAEL, L. T, AYALA-FIERRO, F, CARTER, D. E

    Published in Toxicological sciences (01-06-2000)
    “…The mechanism of arsine (AsH(3)) toxicity is not completely understood. The first cytotoxic effect of AsH(3) is disruption of ion homeostasis, with a…”
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  9. 9

    E2 interference effects in the 12C(α,γ0)16O reaction by Sayre, D B, Brune, C R, Carter, D E, Jacobs, D K, Massey, T N, O'Donnell, J E

    Published in Physical review letters (05-10-2012)
    “…The E1-E2 interference sign between the E(c.m.)=2.68-MeV E2 resonance and an underlying E1 strength has been measured for the first time. An E1-E2 asymmetry…”
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  10. 10

    In vitro tissue specificity for arsine and arsenite toxicity in the rat by AYALA-FIERRO, F, BARBER, D. S, RAEL, L. T, CARTER, D. E

    Published in Toxicological sciences (01-11-1999)
    “…The mechanism of arsine (AsH3) toxicity is not completely understood. In this investigation, we determined AsH3 and arsenite (AsIII) toxicity in Sprague Dawley…”
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  11. 11

    GLUTATHIONE, ALBUMIN, CYSTEINE, AND CYS-GLY EFFECTS ON TOXICITY AND ACCUMULATION OF MERCURIC CHLORIDE IN LLC-PK1 CELLS by Divine, K K, Ayala-Fierro, F, Barber, D S, Carter, D E

    “…Speciation plays a profound if not dominant role in both transport and toxicity of Hg(II). Hg(II) has a high affinity for sulfhydryl groups. The formation…”
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  12. 12

    Determination and metabolism of dithiol chelating agents. XII. Metabolism and pharmacokinetics of sodium 2,3-dimercaptopropane-1-sulfonate in humans by Maiorino, R M, Dart, R C, Carter, D E, Aposhian, H V

    “…The sodium salt of 2,3-dimercaptopropane-1-sulfonic acid (DMPS) is used p.o. for the treatment of chronic lead and Hg intoxication in humans. The metabolism…”
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  13. 13

    SYSTEMIC INDICATORS OF INORGANIC ARSENIC TOXICITY IN FOUR ANIMAL SPECIES by Mitchell, R D, Ayala-Fierro, F, Carter, D E

    “…The effect of arsenic compounds depends on the chemical form and is specific for certain organs. The lack of specific biological indicators for the effects of…”
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  14. 14

    Structural Alterations in the Rat Kidney After Acute Arsine Exposure by Ayala-Fierro, Felix, Baldwin, Ann Linda, Wilson, Lisa May, Valeski, Jan Edward, Carter, Dean Edwin

    Published in Laboratory investigation (01-01-2000)
    “…The mechanism of arsine (AsH3) toxicity is not completely understood. In this investigation, the toxicity of AsH3 and AsH3-produced hemolytic products was…”
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  15. 15

    Inorganic mercury chloride-induced apoptosis in the cultured porcine renal cell line LLC-PK1 by Duncan-Achanzar, K B, Jones, J T, Burke, M F, Carter, D E, Laird, 2nd, H E

    “…HgCl2 is known to be a renal toxin, but its mechanisms of toxicity are not well understood. The cell line LLC-PK1 was used as a model for renal proximal tubule…”
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  16. 16

    Determination and metabolism of dithiol chelating agents: X. In humans, meso-2,3-dimercaptosuccinic acid is bound to plasma proteins via mixed disulfide formation by Maiorino, R M, Akins, J M, Blaha, K, Carter, D E, Aposhian, H V

    “…meso-2,3-Dimercaptosuccinic acid (DMSA) is orally effective for the treatment of chronic lead intoxication in humans. Earlier studies have shown that the…”
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  17. 17

    Effects of acute and chronic arsenic exposure of human-derived keratinocytes in an In Vitro human skin equivalent system: a novel model of human arsenicism by Klimecki, W.T., Borchers, A.H., Egbert, R.E., Nagle, R.B., Carter, D.E., Bowden, G.T.

    Published in Toxicology in vitro (01-02-1997)
    “…An organotypic culture (OTC) of a human keratinocyte cell line (HaCaT) over a human fibroblast-embedded collagen gel was used to model human epidermis in…”
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  18. 18

    Comparative pulmonary toxicity of gallium arsenide, gallium(III) oxide, or arsenic(III) oxide intratracheally instilled into rats by Webb, D R, Wilson, S E, Carter, D E

    Published in Toxicology and applied pharmacology (15-03-1986)
    “…The relative toxicity of gallium arsenide (GaAs) and its metal oxides was assessed by intratracheally instilling particulate suspensions of GaAs (100 mg/kg),…”
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  19. 19

    Interactions of rat red blood cell sulfhydryls with arsenate and arsenite by Winski, S L, Carter, D E

    “…Arsenic-thiol interactions were investigated by determining changes in rat blood sulfhydryls after exposure to arsenate, As(V), or arsenite, As(III)…”
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  20. 20

    Oxidation-Reduction Reactions of Metal Ions by Carter, Dean E.

    Published in Environmental health perspectives (01-02-1995)
    “…Several metal or metalloid ions exist in multiple oxidation states and can undergo electron transfer reactions that are important in biological and…”
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