Search Results - "Carter, CRD"

Abstract P1-13-08: Chemotherapy for Breast Cancer Causes Sustained Alteration In Number and Type of B Lymphocytes by Verma, R, Smalle, N, McCurtin, RE, Horgan, K, Carter, CRD, Hughes, TA

“…Abstract Introduction: The initial immune toxicities of chemotherapy have been reported but longer-term effects are less clear. In order to ascertain if…”
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Alpha and beta chemokines induce NK cell migration and enhance NK- mediated cytolysis by Taub, DD, Sayers, TJ, Carter, CR, Ortaldo, JR

“…Chemokines have been shown to play an important role in both the adhesion and migration of numerous leukocytic cell types, including granulocytes, monocytes,…”
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Tumor-Specific CTL Kill Murine Renal Cancer Cells Using Both Perforin and Fas Ligand-Mediated Lysis In Vitro, But Cause Tumor Regression In Vivo in the Absence of Perforin by Seki, Naoko, Brooks, Alan D, Carter, Clive R. D, Back, Timothy C, Parsoneault, Erin M, Smyth, Mark J, Wiltrout, Robert H, Sayers, Thomas J

“…Kidney cancer is a devastating disease; however, biological therapies have achieved some limited success. The murine renal cancer Renca has been used as a…”
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The significance of carbohydrates on G-CSF: differential sensitivity of G-CSFs to human neutrophil elastase degradation by Carter, Clive R. D., Whitmore, Katie M., Thorpe, Robin

“…It has been reported recently that granulocyte‐colony stimulating factor (G‐CSF) is degraded upon exposure to human neutrophil elastase (HNE), and this has a…”
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Human serum inactivates non-glycosylated but not glycosylated granulocyte colony stimulating factor by a protease dependent mechanism: significance of carbohydrates on the glycosylated molecule by Carter, Clive R.D., Keeble, James R., Thorpe, Robin

“…It has previously been reported that the biological activity of the human hematopoetic cytokine granulocyte colony stimulating factor (G-CSF) was reduced…”
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Treatment of mice with IL-12 DNA constructs leads to augmented NK activity in lungs but low IFN-γ release – Implications for Bordetella pertussis infections following aerosol challenge by Carter, C.R.D., Dagg, B.M., Whitmore, K.M., Keeble, J.R., Asokanathan, C., Rodgers, A., Watanabe, M., Xing, D., Walker, K.B.

“…Interleukin-12 protein has been widely used experimentally in therapeutic and adjuvant settings in the treatment of different diseases including intra-cellular…”
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High dose interleukin‐12 exacerbates Bordetella pertussis infection and is associated with suppression of cell‐mediated immunity in a murine aerosol challenge model by CARTER, C. R. D., DAGG, B. M., WHITMORE, K. M., KEEBLE, J. R., ASOKANATHAN, C., XING, D., WALKER, K. B.

“…SUMMARY The in ‐vivo clearance of Bordetella pertussis infections in murine models in naive mice and animals vaccinated with whole‐cell vaccine is considered…”
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The effect of pertussis whole cell and acellular vaccines on pulmonary immunology in an aerosol challenge model by Carter, Clive R.D., Dagg, Belinda M., Whitmore, Katie M., Keeble, James R., Asokanathan, Cathy, Xing, Dorothy, Walker, K.Barry

“…Recent clinical trials have shown that the new generation of acellular pertussis vaccines (Pa) can confer protection against whooping cough with negligible…”
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Partial degradation of T-cell signal transduction molecules by contaminating granulocytes during protein extraction of splenic T cells from tumor-bearing mice by FRANCO, J. L, GHOSH, P, WILTROUT, R. H, CARTER, C. R. D, ZEA, A. H, MOMOZAKI, N, OCHOA, A. C, LONGO, D. L, SAYERS, T. J, KOMSCHLIES, K. L

“…Flavone-8-acetic acid plus recombinant human interleukin 2 is a successful antitumor therapy in mice bearing the Renca murine renal cell carcinoma. This report…”
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Molecular cloning of the 22–24 kDa excretory-secretory 22U protein of Dirofilaria immitis and other filarial nematode parasites by Frank, GlennR, Wisnewski, Nancy, Brandt, KevinS, Carter, CliveR.D., Jennings, NicolaS, Selkirk, MurrayE

“…Parasitic nematode excretory-secretory (ES) products consist of an ill-defined collection of molecules released by the parasite that have postulated roles in…”
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Cloning and expression of a second human natural killer cell granule tryptase, HNK-Tryp-2/granzyme 3 by Sayers, Thomas J., Lloyd, Andrew R., McVicar, Daniel W., O'Connor, Michael D., Kelly, Janice M., Carter, Clive R. D., Wiltrout, Theresa A., Wiltrout, Robert H., Smyth, Mark J.

“…Cytotoxic lymphocytes possess a number of serine proteases (granzymes) usually localised in cytoplasmic granules. To date, the DNA sequences of four human…”
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Generation of Antigenic Peptides by Lymphocyte Granule Serine Proteases (Granzymes) by Carter, Clive R.D., Sayers, Thomas J., Wiltrout, Robert H., Turcovski-Corrales, Susan M., Taub, Dennis D.

“…We have examined the ability of several serine proteases (granzymes) isolated from the granules of the rat natural killer cell line, RNK, to generate antigenic…”
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Cloning and characterization of a novel NK cell-specific serine protease gene and its functional 5'-flanking sequences by Smyth, M J, Hulett, M D, Thia, K Y, Young, H A, Sayers, T J, Carter, C R, Trapani, J A

“…Rat natural killer cell Met-ase-1 (RNK-Met-1) is a 30,000 M(r) serine protease (granzyme) found in the cytolytic granules of CD3- large granular lymphocytes…”
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The augmentation of lymphokine-activated killer activity following pulsing of human peripheral blood mononuclear cells with recombinant human interleukin-2 by CARTER, C. R. D, HANCOCK, B. W, REES, R. C

“…The short-term exposure of peripheral blood mononuclear cells (PBMC) to recombinant human interleukin-2 (rhIL-2) at 37 degrees C leads to the generation of…”
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