Search Results - "Carter, C. Ross"

CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma by Steele, Colin W., Karim, Saadia A., Leach, Joshua D.G., Bailey, Peter, Upstill-Goddard, Rosanna, Rishi, Loveena, Foth, Mona, Bryson, Sheila, McDaid, Karen, Wilson, Zena, Eberlein, Catherine, Candido, Juliana B., Clarke, Mairi, Nixon, Colin, Connelly, John, Jamieson, Nigel, Carter, C. Ross, Balkwill, Frances, Chang, David K., Evans, T.R. Jeffry, Strathdee, Douglas, Biankin, Andrew V., Nibbs, Robert J.B., Barry, Simon T., Sansom, Owen J., Morton, Jennifer P.

“…CXCR2 has been suggested to have both tumor-promoting and tumor-suppressive properties. Here we show that CXCR2 signaling is upregulated in human pancreatic…”
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MicroRNA Molecular Profiles Associated with Diagnosis, Clinicopathologic Criteria, and Overall Survival in Patients with Resectable Pancreatic Ductal Adenocarcinoma by JAMIESON, Nigel B, MORRAN, Douglas C, MORTON, Jennifer P, ALI, Asif, DICKSON, Euan J, ROSS CARTER, C, SANSOM, Owen J, EVANS, T. R. Jeffry, MCKAY, Colin J, OIEN, Karin A

“…MicroRNAs (miRNA) have potential as diagnostic and prognostic biomarkers and as therapeutic targets in cancer. We sought to establish the relationship between…”
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Tissue Biomarkers for Prognosis in Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-analysis by JAMIESON, Nigel B, CARTER, C. Ross, MCKAY, Colin J, OIEN, Karin A

“…The management of pancreatic ductal adenocarcinoma (PDAC) continues to present a great challenge particularly with regard to prediction of outcome following…”
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SIRT3 & SIRT7: Potential Novel Biomarkers for Determining Outcome in Pancreatic Cancer Patients by McGlynn, Liane M, McCluney, Simon, Jamieson, Nigel B, Thomson, Jackie, MacDonald, Alasdair I, Oien, Karin, Dickson, Euan J, Carter, C Ross, McKay, Colin J, Shiels, Paul G

“…The sirtuin gene family has been linked with tumourigenesis, in both a tumour promoter and suppressor capacity. Information regarding the function of sirtuins…”
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The Prognostic Influence of Resection Margin Clearance Following Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma by Jamieson, Nigel B., Chan, Nigel I. J., Foulis, Alan K., Dickson, Euan J., McKay, Colin J., Carter, C. Ross

“…Introduction The poor overall survival associated with pancreatic ductal adenocarcinoma (PDAC) despite complete resection suggests that occult metastatic…”
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CXCR2 inhibition suppresses acute and chronic pancreatic inflammation by Steele, Colin W, Karim, Saadia A, Foth, Mona, Rishi, Loveena, Leach, Joshua DG, Porter, Ross J, Nixon, Colin, Jeffry Evans, TR, Carter, C Ross, Nibbs, Robert JB, Sansom, Owen J, Morton, Jennifer P

“…Pancreatitis is a significant clinical problem and the lack of effective therapeutic options means that treatment is often palliative rather than curative. A…”
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Serum amylase on the night of surgery predicts clinically significant pancreatic fistula after pancreaticoduodenectomy by Palani Velu, Lavanniya K, Chandrabalan, Vishnu V, Jabbar, Salman, McMillan, Donald C, McKay, Colin J, Carter, C. Ross, Jamieson, Nigel B, Dickson, Euan J

“…Abstract Objectives Drainage after pancreaticoduodenectomy (PD) remains controversial because the risk for uncontrolled postoperative pancreatic fistula (POPF)…”
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Feasibility and clinical utility of endoscopic ultrasound guided biopsy of pancreatic cancer for next-generation molecular profiling by Dreyer, Stephan B, Jamieson, Nigel B, Evers, Lisa, Duthie, Fraser, Cooke, Susie, Marshall, John, Beraldi, Dario, Knight, Stephen, Upstill-Goddard, Rosanna, Dickson, Euan J, Carter, C Ross, McKay, Colin J, Biankin, Andrew V, Chang, David K

“…Next-generation sequencing is enabling molecularly guided therapy for many cancer types, yet failure rates remain relatively high in pancreatic cancer (PC)…”
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Minimally Invasive Necrosectomy Techniques in Severe Acute Pancreatitis: Role of Percutaneous Necrosectomy and Video-Assisted Retroperitoneal Debridement by Logue, Jennifer A., Carter, C. Ross

“…Consensus advocating a principle of early organ support, nutritional optimisation, followed ideally by delayed minimally invasive intervention within a…”
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Pre-operative cardiopulmonary exercise testing predicts adverse post-operative events and non-progression to adjuvant therapy after major pancreatic surgery by Chandrabalan, Vishnu V, McMillan, Donald C, Carter, Roger, Kinsella, John, McKay, Colin J, Carter, C. Ross, Dickson, Euan J

“…Abstract Background Surgery followed by chemotherapy is the primary modality of cure for patients with resectable pancreatic cancer but is associated with…”
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Routine Drainage After Pancreaticoduodenectomy: Serum Amylase Can Guide Early, Selective Drain Removal by Palani Velu, Lavanniya K, Chandrabalan, Vishnuvardhan, McMillan, Donald C, McKay, Colin J, Carter, C Ross, Jamieson, Nigel B, Dickson, Euan J

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Hypermutation In Pancreatic Cancer by Humphris, Jeremy L, Patch, Ann-Marie, Nones, Katia, Bailey, Peter J, Johns, Amber L, McKay, Skye, Chang, David K, Miller, David K, Pajic, Marina, Kassahn, Karin S, Quinn, Michael C.J, Bruxner, Timothy J.C, Christ, Angelika N, Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Stone, Andrew, Wilson, Peter J, Anderson, Matthew, Fink, J. Lynn, Holmes, Oliver, Kazakoff, Stephen, Leonard, Conrad, Newell, Felicity, Waddell, Nick, Wood, Scott, Mead, Ronald S, Xu, Qinying, Wu, Jianmin, Pinese, Mark, Cowley, Mark J, Jones, Marc D, Nagrial, Adnan M, Chin, Venessa T, Chantrill, Lorraine A, Mawson, Amanda, Chou, Angela, Scarlett, Christopher J, Pinho, Andreia V, Rooman, Ilse, Giry-Laterriere, Marc, Samra, Jaswinder S, Kench, James G, Merrett, Neil D, Toon, Christopher W, Epari, Krishna, Nguyen, Nam Q, Barbour, Andrew, Zeps, Nikolajs, Jamieson, Nigel B, McKay, Colin J, Carter, C. Ross, Dickson, Euan J, Graham, Janet S, Duthie, Fraser, Oien, Karin, Hair, Jane, Morton, Jennifer P, Sansom, Owen J, Grützmann, Robert, Hruban, Ralph H, Maitra, Anirban, Iacobuzio-Donahue, Christine A, Schulick, Richard D, Wolfgang, Christopher L, Morgan, Richard A, Lawlor, Rita T, Rusev, Borislav, Corbo, Vincenzo, Salvia, Roberto, Cataldo, Ivana, Tortora, Giampaolo, Tempero, Margaret A, Hofmann, Oliver, Eshleman, James R, Pilarsky, Christian, Scarpa, Aldo, Musgrove, Elizabeth A, Gill, Anthony J, Pearson, John V, Grimmond, Sean M, Waddell, Nicola, Biankin, Andrew V

“…Pancreatic cancer is molecularly diverse, with few effective therapies. Increased mutation burden and defective DNA repair are associated with response to…”
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RE: nab-Paclitaxel Plus Gemcitabine for Metastatic Pancreatic Cancer: Long-Term Survival From a Phase III Trial by Palani Velu, Lavanniya K, Steele, Colin W, Dickson, Euan J, Carter, C Ross, McKay, Colin J, Horgan, Paul G, McMillan, Donald C, Jamieson, Nigel B

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Activation of the IL-6R/Jak/Stat Pathway is Associated with a Poor Outcome in Resected Pancreatic Ductal Adenocarcinoma by Denley, Simon M., Jamieson, Nigel B., McCall, Pamela, Oien, Karin A., Morton, Jennifer P., Carter, C. Ross, Edwards, Joanne, McKay, Colin J.

“…Background and Objective Chronic localized pancreatic inflammation in the form of chronic pancreatitis is an established risk factor for human pancreatic…”
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Targeting mTOR dependency in pancreatic cancer by Morran, Douglas C, Wu, Jianmin, Jamieson, Nigel B, Mrowinska, Agata, Kalna, Gabriela, Karim, Saadia A, Au, Amy Y M, Scarlett, Christopher J, Chang, David K, Pajak, Malgorzata Z, Oien, Karin A, McKay, Colin J, Carter, C Ross, Gillen, Gerry, Champion, Sue, Pimlott, Sally L, Anderson, Kurt I, Evans, T R Jeffry, Grimmond, Sean M, Biankin, Andrew V, Sansom, Owen J, Morton, Jennifer P

“…Pancreatic cancer is a leading cause of cancer-related death in the Western world. Current chemotherapy regimens have modest survival benefit. Thus, novel,…”
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Fascin Is Regulated by Slug, Promotes Progression of Pancreatic Cancer in Mice, and Is Associated With Patient Outcomes by Li, Ang, Morton, Jennifer P, Ma, YaFeng, Karim, Saadia A, Zhou, Yan, Faller, William J, Woodham, Emma F, Morris, Hayley T, Stevenson, Richard P, Juin, Amelie, Jamieson, Nigel B, MacKay, Colin J, Carter, C. Ross, Leung, Hing Y, Yamashiro, Shigeko, Blyth, Karen, Sansom, Owen J, Machesky, Laura M

“…Background & Aims Pancreatic ductal adenocarcinoma (PDAC) is often lethal because it is highly invasive and metastasizes rapidly. The actin-bundling protein…”
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IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival by Lunardi, Serena, Jamieson, Nigel B, Lim, Su Yin, Griffiths, Kristin L, Carvalho-Gaspar, Manuela, Al-Assar, Osama, Yameen, Sabira, Carter, Ross C, McKay, Colin J, Spoletini, Gabriele, D'Ugo, Stefano, Silva, Michael A, Sansom, Owen J, Janssen, Klaus-Peter, Muschel, Ruth J, Brunner, Thomas B

“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by an abundant desmoplastic reaction driven by pancreatic stellate cells (PSCs) that contributes to…”
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Histomolecular Phenotypes and Outcome in Adenocarcinoma of the Ampulla of Vater by CHANG, David K, JAMIESON, Nigel B, NAGRIAL, Adnan M, CHANTRILL, Lorraine A, CHIN, Venessa T, PINHO, Andreia V, ROOMAN, Ilse, COWLEY, Mark J, JIANMIN WU, MEAD, R. Scott, COLVIN, Emily K, SAMRA, Jaswinder S, JOHNS, Amber L, CORBO, Vincenzo, BASSI, Claudio, FALCONI, Massimo, LAWLOR, Rita T, CRIPPA, Stefano, SPERANDIO, Nicola, BERSANI, Samantha, DICKSON, Euan J, MOHAMED, Mohamed A. A, OIEN, Karin A, SCARLETT, Christopher J, FOULIS, Alan K, MUSGROVE, Elizabeth A, SUTHERLAND, Robert L, KENCH, James G, CARTER, C. Ross, GILL, Anthony J, SCARPA, Aldo, MCKAY, Colin J, BIANKIN, Andrew V, PAJIC, Marina, CHOU, Angela, PINESE, Mark, HUMPHRIS, Jeremy L, JONES, Marc D, TOON, Christopher

“…Individuals with adenocarcinoma of the ampulla of Vater demonstrate a broad range of outcomes, presumably because these cancers may arise from any one of the…”
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The Relationship Between Tumor Inflammatory Cell Infiltrate and Outcome in Patients with Pancreatic Ductal Adenocarcinoma by Jamieson, Nigel B., Mohamed, Mohamed, Oien, Karin A., Foulis, Alan K., Dickson, Euan J., Imrie, Clem W., Carter, C. Ross, McKay, Colin J., McMillan, Donald C.

“…Background The tumor-associated inflammatory cell infiltrate is recognized to have prognostic value in various common solid tumors. However, the prognostic…”
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Recommended Workflow Methodology in the Creation of an Interactive Application for Patient's Diagnosed with Pancreatic Cancer by Knight, Olivia, Carter, C Ross, Loranger, Brian, Rea, Paul M

“…Pancreatic cancer is a leading cause of cancer related deaths in the UK. However, public knowledge and understanding of the pancreas is generally poor,…”
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