Search Results - "Carter, Bob S."

Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles by Reátegui, Eduardo, van der Vos, Kristan E., Lai, Charles P., Zeinali, Mahnaz, Atai, Nadia A., Aldikacti, Berent, Floyd, Frederick P., H. Khankhel, Aimal, Thapar, Vishal, Hochberg, Fred H., Sequist, Lecia V., Nahed, Brian V., S. Carter, Bob, Toner, Mehmet, Balaj, Leonora, T. Ting, David, Breakefield, Xandra O., Stott, Shannon L.

“…Extracellular vesicles (EVs) carry RNA, DNA, proteins, and lipids. Specifically, tumor-derived EVs have the potential to be utilized as disease-specific…”
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Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma by Shao, Huilin, Chung, Jaehoon, Lee, Kyungheon, Balaj, Leonora, Min, Changwook, Carter, Bob S., Hochberg, Fred H., Breakefield, Xandra O., Lee, Hakho, Weissleder, Ralph

“…Real-time monitoring of drug efficacy in glioblastoma multiforme (GBM) is a major clinical problem as serial re-biopsy of primary tumours is often not a…”
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Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy by Shao, Huilin, Chung, Jaehoon, Balaj, Leonora, Charest, Alain, Bigner, Darell D, Carter, Bob S, Hochberg, Fred H, Breakefield, Xandra O, Weissleder, Ralph, Lee, Hakho

“…Cancer cells shed large numbers of small, membrane-bound microvesicles (MVs) into the circulation, which have diagnostic potential but have proved difficult to…”
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Extracellular Vesicles in Glioblastoma Tumor Microenvironment by Yekula, Anuroop, Yekula, Anudeep, Muralidharan, Koushik, Kang, Keiko, Carter, Bob S, Balaj, Leonora

“…Glioblastomas (GBM) are highly aggressive primary brain tumors. Complex and dynamic tumor microenvironment (TME) plays a crucial role in the sustained growth,…”
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Rapid Isolation and Detection of Exosomes and Associated Biomarkers from Plasma by Ibsen, Stuart D, Wright, Jennifer, Lewis, Jean M, Kim, Sejung, Ko, Seo-Yeon, Ong, Jiye, Manouchehri, Sareh, Vyas, Ankit, Akers, Johnny, Chen, Clark C, Carter, Bob S, Esener, Sadik C, Heller, Michael J

“…Exosomes found in the circulation are a primary source of important cancer-related RNA and protein biomarkers that are expected to lead to early detection,…”
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Endonasal instrumentation and aerosolization risk in the era of COVID‐19: simulation, literature review, and proposed mitigation strategies by Workman, Alan D., Welling, D. Bradley, Carter, Bob S., Curry, William T., Holbrook, Eric H., Gray, Stacey T., Scangas, George A., Bleier, Benjamin S.

“…Background International experience with coronavirus 2019 (COVID‐19) suggests it poses a significant risk of infectious transmission to skull base surgeons,…”
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MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development by Akers, Johnny C, Ramakrishnan, Valya, Kim, Ryan, Skog, Johan, Nakano, Ichiro, Pingle, Sandeep, Kalinina, Juliya, Hua, Wei, Kesari, Santosh, Mao, Ying, Breakefield, Xandra O, Hochberg, Fred H, Van Meir, Erwin G, Carter, Bob S, Chen, Clark C

“…Glioblastoma cells secrete extra-cellular vesicles (EVs) containing microRNAs (miRNAs). Analysis of these EV miRNAs in the bio-fluids of afflicted patients…”
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Airborne Aerosol Generation During Endonasal Procedures in the Era of COVID-19: Risks and Recommendations by Workman, Alan D., Jafari, Aria, Welling, D. Bradley, Varvares, Mark A., Gray, Stacey T., Holbrook, Eric H., Scangas, George A., Xiao, Roy, Carter, Bob S., Curry, William T., Bleier, Benjamin S.

“…Objective In the era of SARS-CoV-2, the risk of infectious airborne aerosol generation during otolaryngologic procedures has been an area of increasing…”
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Characterization and Correction of Geometric Distortions in 814 Diffusion Weighted Images by Treiber, Jeffrey Mark, White, Nathan S, Steed, Tyler Christian, Bartsch, Hauke, Holland, Dominic, Farid, Nikdokht, McDonald, Carrie R, Carter, Bob S, Dale, Anders Martin, Chen, Clark C

“…Diffusion Weighted Imaging (DWI), which is based on Echo Planar Imaging (EPI) protocols, is becoming increasingly important for neurosurgical applications…”
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Pluripotent stem cell-based therapy for Parkinson's disease: Current status and future prospects by Sonntag, Kai-C, Song, Bin, Lee, Nayeon, Jung, Jin Hyuk, Cha, Young, Leblanc, Pierre, Neff, Carolyn, Kong, Sek Won, Carter, Bob S, Schweitzer, Jeffrey, Kim, Kwang-Soo

“…Parkinson's disease (PD) is one of the most common neurodegenerative disorders, which affects about 0.3% of the general population. As the population in the…”
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Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients by Figueroa, Javier M, Skog, Johan, Akers, Johnny, Li, Hongying, Komotar, Ricardo, Jensen, Randy, Ringel, Florian, Yang, Isaac, Kalkanis, Steven, Thompson, Reid, LoGuidice, Lori, Berghoff, Emily, Parsa, Andrew, Liau, Linda, Curry, William, Cahill, Daniel, Bettegowda, Chetan, Lang, Frederick F, Chiocca, E Antonio, Henson, John, Kim, Ryan, Breakefield, Xandra, Chen, Clark, Messer, Karen, Hochberg, Fred, Carter, Bob S

“…RNAs within extracellular vesicles (EVs) have potential as diagnostic biomarkers for patients with cancer and are identified in a variety of biofluids…”
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Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile by Winston, Charisse N, Goetzl, Edward J, Akers, Johnny C, Carter, Bob S, Rockenstein, Edward M, Galasko, Douglas, Masliah, Eliezer, Rissman, Robert A

“…Abstract Introduction Levels of Alzheimer's disease (AD)-related proteins in plasma neuronal derived exosomes (NDEs) were quantified to identify biomarkers for…”
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TERT Promoter Mutation Analysis for Blood-Based Diagnosis and Monitoring of Gliomas by Muralidharan, Koushik, Yekula, Anudeep, Small, Julia L, Rosh, Zachary S, Kang, Keiko M, Wang, Lan, Lau, Spencer, Zhang, Hui, Lee, Hakho, Bettegowda, Chetan, Chicoine, Michael R, Kalkanis, Steven N, Shankar, Ganesh M, Nahed, Brian V, Curry, William T, Jones, Pamela S, Cahill, Daniel P, Balaj, Leonora, Carter, Bob S

“…Liquid biopsy offers a minimally invasive tool to diagnose and monitor the heterogeneous molecular landscape of tumors over time and therapy. Detection of…”
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CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma by Choi, Bryan D., Yu, Xiaoling, Castano, Ana P., Darr, Henia, Henderson, Daniel B., Bouffard, Amanda A., Larson, Rebecca C., Scarfò, Irene, Bailey, Stefanie R., Gerhard, Genevieve M., Frigault, Matthew J., Leick, Mark B., Schmidts, Andrea, Sagert, Jason G., Curry, William T., Carter, Bob S., Maus, Marcela V.

“…Despite remarkable success in the treatment of hematological malignancies, CAR T-cell therapies for solid tumors have floundered, in large part due to local…”
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Blood-based biomarkers for the diagnosis and monitoring of gliomas by Zachariah, Marcus A, Oliveira-Costa, Joao Paulo, Carter, Bob S, Stott, Shannon L, Nahed, Brian V

“…Monitoring patient response to treatment is challenging for most cancers, but it is particularly difficult in glioblastoma multiform, the most common and…”
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Comparative Analysis of Technologies for Quantifying Extracellular Vesicles (EVs) in Clinical Cerebrospinal Fluids (CSF) by Akers, Johnny C, Ramakrishnan, Valya, Nolan, John P, Duggan, Erika, Fu, Chia-Chun, Hochberg, Fred H, Chen, Clark C, Carter, Bob S

“…Extracellular vesicles (EVs) have emerged as a promising biomarker platform for glioblastoma patients. However, the optimal method for quantitative assessment…”
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Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma by Sahin, Ayguen, Sanchez, Carlos, Bullain, Szofia, Waterman, Peter, Weissleder, Ralph, Carter, Bob S

“…Glioblastoma multiforme (GBM) is the most aggressive and deadly form of adult brain cancer. Despite of many attempts to identify potential therapies for this…”
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Oligodendroglioma resection: a Surveillance, Epidemiology, and End Results (SEER) analysis by Alattar, Ali A, Brandel, Michael G, Hirshman, Brian R, Dong, Xuezhi, Carroll, Kate T, Ali, Mir Amaan, Carter, Bob S, Chen, Clark C

“…OBJECTIVE The available evidence suggests that the clinical benefits of extended resection are limited for chemosensitive tumors, such as primary CNS lymphoma…”
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miRNA contents of cerebrospinal fluid extracellular vesicles in glioblastoma patients by Akers, Johnny C., Ramakrishnan, Valya, Kim, Ryan, Phillips, Shirley, Kaimal, Vivek, Mao, Ying, Hua, Wei, Yang, Isaac, Fu, Chia-Chun, Nolan, John, Nakano, Ichiro, Yang, Yuanfan, Beaulieu, Martin, Carter, Bob S., Chen, Clark C.

“…Analysis of extracellular vesicles (EVs) derived from plasma or cerebrospinal fluid (CSF) has emerged as a promising biomarker platform for therapeutic…”
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Microfluidic isolation and transcriptome analysis of serum microvesicles by Chen, Chihchen, Skog, Johan, Hsu, Chia-Hsien, Lessard, Ryan T, Balaj, Leonora, Wurdinger, Thomas, Carter, Bob S, Breakefield, Xandra O, Toner, Mehmet, Irimia, Daniel

“…Microvesicles (exosomes) shed from both normal and cancerous cells may serve as means of intercellular communication. These microvesicles carry proteins,…”
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