Search Results - "Carroll, Sherry L"

N-{3-[2-(4-Alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy Derivatives as Acetyl-CoA Carboxylase InhibitorsImprovement of Cardiovascular and Neurological Liabilities via Structural Modifications by Gu, Yu Gui, Weitzberg, Moshe, Clark, Richard F, Xu, Xiangdong, Li, Qun, Lubbers, Nathan L, Yang, Yi, Beno, David W. A, Widomski, Deborah L, Zhang, Tianyuan, Hansen, T. Matthew, Keyes, Robert F, Waring, Jeffrey F, Carroll, Sherry L, Wang, Xiaojun, Wang, Rongqi, Healan-Greenberg, Christine H, Blomme, Eric A, Beutel, Bruce A, Sham, Hing L, Camp, Heidi S

“…A preliminary safety evaluation of ACC2 inhibitor 1-(S) revealed serious neurological and cardiovascular liabilities of this chemotype. A systematic…”
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N -{3-[2-(4-Alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy Derivatives as Acetyl-CoA Carboxylase InhibitorsImprovement of Cardiovascular and Neurological Liabilities via Structural Modifications by Gu, Yu Gui, Weitzberg, Moshe, Clark, Richard F., Xu, Xiangdong, Li, Qun, Lubbers, Nathan L., Yang, Yi, Beno, David W. A., Widomski, Deborah L., Zhang, Tianyuan, Hansen, T. Matthew, Keyes, Robert F., Waring, Jeffrey F., Carroll, Sherry L., Wang, Xiaojun, Wang, Rongqi, Healan-Greenberg, Christine H., Blomme, Eric A., Beutel, Bruce A., Sham, Hing L., Camp, Heidi S.

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