Search Results - "Carroll, P V"

Immune checkpoint inhibitor-related hypophysitis and endocrine dysfunction: clinical review by Joshi, M.N, Whitelaw, B.C., Palomar, M.T.P., Wu, Y., Carroll, P.V.

“…Summary Immune checkpoint inhibitors are a new and effective class of cancer therapy, with ipilimumab being the most established drug in this category. The…”
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The Prevalence and Natural History of Pituitary Hemorrhage in Prolactinoma by Sarwar, K. N, Huda, M. S. B, Van de Velde, V, Hopkins, L, Luck, S, Preston, R, McGowan, B. M, Carroll, P. V, Powrie, J. K

“…Context: Incidental pituitary hemorrhage, without full pituitary apoplexy, is a recognized radiological finding, but little information exists on its clinical…”
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Factors determining the remission of microprolactinomas after dopamine agonist withdrawal by Huda, M. S. B., Athauda, N. B., Teh, M. M., Carroll, P. V., Powrie, J. K.

“…Summary Background  Withdrawal of dopamine agonist (DA) therapy in the management of microprolactinoma is common practice, but it is unclear which patients are…”
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Comparison of Continuation or Cessation of Growth Hormone (GH) Therapy on Body Composition and Metabolic Status in Adolescents with Severe GH Deficiency at Completion of Linear Growth by Carroll, P. V., Drake, W. M., Maher, K. T., Metcalfe, K., Shaw, N. J., Dunger, D. B., Cheetham, T. D., Camacho-Hübner, C., Savage, M. O., Monson, J. P.

“…Although GH replacement improves the features of GH deficiency (GHD) in adults, it has yet to be established whether cessation of GH at completion of childhood…”
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Genetic predictors of cardiovascular morbidity in Bardet-Biedl syndrome by Forsythe, E., Sparks, K., Hoskins, B.E., Bagkeris, E., McGowan, B.M., Carroll, P.V., Huda, M.S.B., Mujahid, S., Peters, C., Barrett, T., Mohammed, S., Beales, P.L.

“…Bardet–Biedl syndrome is a rare ciliopathy characterized by retinal dystrophy, obesity, intellectual disability, polydactyly, hypogonadism and renal…”
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Cerebral cavernoma: an emerging long-term consequence of external beam radiation in childhood by Liu, Y., Preston, R., Thomas, S. M., Brackenridge, A., Carroll, P. V.

“…Summary The long‐term effects of cranial external beam radiotherapy are emerging as survival rates for cerebral tumours improve. Cerebral cavernoma are a…”
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The Effect of Cessation of Growth Hormone (GH) Therapy on Bone Mineral Accretion in GH-Deficient Adolescents at the Completion of Linear Growth by Drake, W. M., Carroll, P. V., Maher, K. T., Metcalfe, K. A., Camacho-Hübner, C., Shaw, N. J., Dunger, D. B., Cheetham, T. D., Savage, M. O., Monson, J. P.

“…In many countries, treatment of childhood-onset GH deficiency (GHD) with GH ceases when linear growth is complete. Peak bone mass occurs several years after…”
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Thomas Addison's disease after 154 years: modern diagnostic perspectives on an old condition by Leelarathna, L., Powrie, J.K., Carroll, P.V.

“…Thomas Addison was first to describe adrenocortical failure in 1855. Despite advances in the treatment of this condition, the diagnosis is still often delayed…”
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The effects of growth hormone deficiency and replacement on glucocorticoid exposure in hypopituitary patients on cortisone acetate and hydrocortisone replacement by Swords, F. M., Carroll, P. V., Kisalu, J., Wood, P. J., Taylor, N. F., Monson, J. P.

“…Summary objective  11β‐hydroxysteroid dehydrogenase type 1 (11βHSD1) converts inactive cortisone to active cortisol. 11βHSD1 activity is increased in GH…”
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Simultaneous Cushing's disease and tuberous sclerosis; a potential role for TSC in pituitary ontogeny by Tigas, S., Carroll, P. V., Jones, R., Bingham, E., Russell-Jones, D., Powell, M., Scobie, I. N.

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Successful treatment of childhood-onset Cushing's disease is associated with persistent reduction in growth hormone secretion by Carroll, P. V., Monson, J. P., Grossman, A. B., Besser, G. M., Plowman, P. N., Afshar, F., Savage, M. O.

“…Summary objective  Although Cushing's disease (CD) rarely occurs in childhood, affected children commonly fail to achieve predicted adult height…”
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metabolic consequences of critical illness: acute effects on glutamine and protein metabolism by Jackson, N.C, Carroll, P.V, Russell-Jones, D.L, Sonksen, P.H, Treacher, D.F, Umpleby, A.M

“…Net protein loss and large decreases in plasma glutamine concentration are characteristics of critical illness. We have used [2-15N]glutamine and…”
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Adjustable Gastric Banding and Sleeve Gastrectomy in Bardet-Biedl Syndrome by Mujahid, S., Huda, M. S. B., Beales, P, Carroll, P. V., McGowan, B. M.

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18Flurodeoxyglucose positron emission tomography in the localization of ectopic ACTH-secreting neuroendocrine tumours by Kumar, J., Spring, M, Carroll, P. V., Barrington, S. F., Powrie, J. K.

“…Summary Objective  Neuroendocrine tumours (NET) are a rare cause of Cushing's syndrome. These tumours can be very small and therefore difficult to identify…”
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Effects of glutamine supplementation, GH, and IGF-I on glutamine metabolism in critically ill patients by Jackson, N C, Carroll, P V, Russell-Jones, D L, Sönksen, P H, Treacher, D F, Umpleby, A M

“…During critical illness glutamine deficiency may develop. Glutamine supplementation can restore plasma concentration to normal, but the effect on glutamine…”
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IGF-I treatment in adults with type 1 diabetes: effects on glucose and protein metabolism in the fasting state and during a hyperinsulinemic-euglycemic amino acid clamp by CARROLL, P. V, CHRIST, E. R, UMPLEBY, A. M, GOWRIE, I, JACKSON, N, BOWES, S. B, HOVORKA, R, CROOS, P, SÖNKSEN, P. H, RUSSELL-JONES, D. L

“…IGF-I treatment in adults with type 1 diabetes: effects on glucose and protein metabolism in the fasting state and during a hyperinsulinemic-euglycemic amino…”
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Transitional care of GH deficiency: when to stop GH therapy by Savage, MO, Drake, WM, Carroll, PV, Monson, JP

“…While the benefits of growth hormone (GH) therapy in adult hypopituitary patients with GH deficiency (GHD) are established, the role of continued GH therapy…”
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Erratum to: Adjustable Gastric Banding and Sleeve Gastrectomy in Bardet-Biedl Syndrome by Mujahid, S., Huda, M. S. B., Beales, P., Carroll, P. V., McGowan, B. M.

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Growth Hormone Replacement in Adults with Growth Hormone Deficiency: Assessment of Current Knowledge by Carroll, Paul V., Christ, Emanuel R., Sönksen, Peter H.

“…The recent availability of recombinant human growth hormone (GH) has led to intense investigation of the consequences of adult GH deficiency (GHD) and the…”
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Normal VLDL metabolism despite altered lipoprotein composition in type 1 diabetes mellitus by Christ, E. R., Carroll, P. V., Albany, E., Umpleby, A. M., Lumb, P. J., Wierzbicki, A. S., Simpson, H. L., Sönksen, P. H., Russell-Jones, D. L.

“…OBJECTIVES Patients with type 1 diabetes are at increased risk of cardiovascular disease, which may be related to abnormal lipid metabolism. Secretion and…”
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