Search Results - "Carrithers, S. L."

Guanylyl Cyclase C is a Selective Marker for Metastatic Colorectal Tumors in Human Extraintestinal Tissues by Carrithers, S. L., Barber, M. T., Biswas, S., Parkinson, S. J., Park, P. K., Goldstein, S. D., Waldman, S. A.

“…Guanylyl cyclase C (GCC) has been detected only in intestinal mucosa and colon carcinoma cells of placental mammals. However, this receptor has been identified…”
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Diarrhea or Colorectal Cancer: Can Bacterial Toxins Serve as a Treatment for Colon Cancer? by Carrithers, S. L.

“…Although the epidemiology of colon cancer remains poorly understood, there is clearly an unexplained inverse relationship between the incidence of colorectal…”
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Formyl peptide receptors are coupled to multiple mitogen-activated protein kinase cascades by distinct signal transduction pathways: role in activation of reduced nicotinamide adenine dinucleotide oxidase by Rane, MJ, Carrithers, SL, Arthur, JM, Klein, JB, McLeish, KR

“…Formyl peptide receptor activation of three mitogen-activated protein kinase (MAPK) cascades, extracellular signal-regulated kinases (ERKs), N-terminal kinases…”
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Site-specific effects of dietary salt intake on guanylin and uroguanylin mRNA expression in rat intestine by Carrithers, S.L, Jackson, B.A, Cai, W.Y, Greenberg, R.N, Ott, C.E

“…Guanylin and uroguanylin are newly discovered intestinal peptides that have been shown to affect NaCl transport in both the intestine and kidney. The present…”
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Guanylyl cyclase-C receptor mRNA distribution along the rat nephron by Carrithers, S.L., Taylor, B., Cai, W.Y., Johnson, B.R., Ott, C.E., Greenberg, R.N., Jackson, B.A.

“…Guanylin (GN) and uroguanylin (UGN) are two recently identified peptides that have been shown to affect water and electrolyte transport in both the intestine…”
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Escherichia coli heat-stable toxin receptors in human colonic tumors by Carrithers, S L, Parkinson, S J, Goldstein, S, Park, P, Robertson, D C, Waldman, S A

“…Escherichia coli heat-stable enterotoxins (ST) are small peptides of 18 or 19 amino acids that bind to specific cell surface receptors located on the…”
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Renal effects of uroguanylin and guanylin in vivo by Carrithers, S L, Hill, M J, Johnson, B R, O'Hara, S M, Jackson, B A, Ott, C E, Lorenz, J, Mann, E A, Giannella, R A, Forte, L R, Greenberg, R N

“…Uroguanylin and guanylin are newly discovered endogenous heat-stable peptides that bind to and activate a membrane bound guanylyl cyclase signaling receptor…”
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Escherichia coli heat-stable enterotoxin receptors. A novel marker for colorectal tumors by Carrithers, S L, Parkinson, S J, Goldstein, S D, Park, P K, Urbanski, R W, Waldman, S A

“…Receptors for Escherichia coli heat-stable toxin (ST) are selectively expressed in membranes of intestinal mucosa cells and colon carcinoma cells in vitro,…”
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Opposing adenine nucleotide-dependent pathways regulate guanylyl cyclase C in rat intestine by Parkinson, S J, Carrithers, S L, Waldman, S A

“…Opposing adenine nucleotide-dependent pathways regulating guanylyl cyclase C (GC-C) in rat intestinal membranes have been identified and characterized. ATP…”
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Hypotensive mechanisms of amifostine by Ryan, S V, Carrithers, S L, Parkinson, S J, Skurk, C, Nuss, C, Pooler, P M, Owen, C S, Lefer, A M, Waldman, S A

“…Amifostine, a chemo- and radioprotective agent developed as adjunctive therapy for malignancies, induces hypotension after approximately 20% of patient…”
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Sequential methylation of 2-mercaptoethanol to the dimethyl sulfonium ion, 2-(dimethylthio)ethanol, in vivo and in vitro by Carrithers, S L, Hoffman, J L

“…Thioether methyltransferase (S-adenosyl-L-methionine: thioether S-methyltransferase; EC 2.1.1.96) catalyzes the methylation of X in compounds of the type…”
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Increased urinary excretion of uroguanylin in patients with congestive heart failure by Carrithers, S L, Eber, S L, Forte, L R, Greenberg, R N

“…Uroguanylin is a small-molecular-weight peptide that activates membrane-bound receptor-guanylate cyclases in the intestine, kidney, and other epithelia…”
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Renal effects of serine-7 analog of lymphoguanylin in ex vivo rat kidney by Fonteles, M C, Carrithers, S L, Monteiro, H S, Carvalho, A F, Coelho, G R, Greenberg, R N, Forte, L R

“…Guanylin and uroguanylin compose a family of natriuretic, diuretic, and kaliuretic peptides that bind to and activate apical membrane receptor guanylyl cyclase…”
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Rat Guanylyl Cyclase C Expressed in COS-7 Cells Exhibits Multiple Affinities for Escherichia coli Heat-Stable Enterotoxin by Deshmane, Sujata P, Carrithers, Steve L, Parkinson, Scott J, Crupper, Scott S, Robertson, Donald C, Waldman, Scott A

“…Intestinal cells exhibit binding sites with different affinities for Escherichia coli heat-stable enterotoxin (ST) and guanylin, suggesting the existence of…”
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Guanylin and uroguanylin induce natriuresis in mice lacking guanylyl cyclase-C receptor by Carrithers, Stephen L., Ott, Cobern E., Hill, Michael J., Johnson, Brett R., Cai, Weiyan, Chang, Jason J., Shah, Rajesh G., Sun, Congmei, Mann, Elizabeth A., Fonteles, Manasses C., Forte, Leonard R., Jackson, Brian A., Giannella, Ralph A., Greenberg, Richard N.

“…Guanylin and uroguanylin induce natriuresis in mice lacking guanylyl cyclase-C receptor. Guanylin (GN) and uroguanylin (UGN) are intestinally derived peptide…”
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Internalization of E. coli ST mediated by guanylyl cyclase C in T84 human colon carcinoma cells by Urbanski, R., Carrithers, S.L., Waldman, S.A.

“…Internalization of Escherichia coli heat-stable enterotoxin (ST) mediated by guanylyl cyclase C was examined in T84 human colon carcinoma cells…”
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Internalization of E. coli ST mediated by guanylyl cyclase C in T84 human colon carcinoma cells by Urbanski, R, Carrithers, S L, Waldman, S A

“…Internalization of Escherichia coli heat-stable enterotoxin (ST) mediated by guanylyl cyclase C was examined in T84 human colon carcinoma cells…”
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Guanylin and its Lysine‐Containing Analogue in the Isolated Perfused Rat Kidney: Interaction with Chymotrypsin Inhibitor by Santos‐Neto, Messias S., Carrithers, Stephen L., Carvalho, André F., Monteiro, Helena S. A., Greenberg, Richard N., Forte, Leonard R., Fonteles, Manassés C.

“…: Guanylin and uroguanylin are two novel peptides that activate membrane‐bound guanylate cyclases found in the kidney and intestine, influencing fluid and…”
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