Search Results - "Carrington, Mary"

Immunogenetics of HIV disease by Martin, Maureen P., Carrington, Mary

“…Summary Host genetic factors are a major contributing factor to the inter‐individual variation observed in response to human immunodeficiency virus (HIV)…”
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High HLA-DP Expression and Graft-versus-Host Disease by Petersdorf, Effie W, Malkki, Mari, O’hUigin, Colm, Carrington, Mary, Gooley, Ted, Haagenson, Michael D, Horowitz, Mary M, Spellman, Stephen R, Wang, Tao, Stevenson, Philip

“…When the donor and recipient are mismatched at HLA-DPB1, the risk of graft-versus-host disease is high. The authors found that when the donor has a particular…”
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HLA Heterozygote Advantage against HIV-1 Is Driven by Quantitative and Qualitative Differences in HLA Allele-Specific Peptide Presentation by Arora, Jatin, Pierini, Federica, McLaren, Paul J, Carrington, Mary, Fellay, Jacques, Lenz, Tobias L

“…Pathogen-mediated balancing selection is regarded as a key driver of host immunogenetic diversity. A hallmark for balancing selection in humans is the…”
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Relative expression levels of the HLA class-I proteins in normal and HIV-infected cells by Apps, Richard, Meng, Zhaojing, Del Prete, Gregory Q, Lifson, Jeffrey D, Zhou, Ming, Carrington, Mary

“…The expression level of HLA class-I proteins is known to influence pathological outcomes: pathogens downregulate HLA to evade host immune responses, host…”
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KIR and disease: a model system or system of models? by Khakoo, Salim I., Carrington, Mary

“…The discovery of an unexpected level of diversity among the killer cell immunoglobulin‐like receptors has led to a search for their role in human disease. Due…”
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Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1 by Garcia-Beltran, Wilfredo F, Hölzemer, Angelique, Martrus, Gloria, Chung, Amy W, Pacheco, Yovana, Simoneau, Camille R, Rucevic, Marijana, Lamothe-Molina, Pedro A, Pertel, Thomas, Kim, Tae-Eun, Dugan, Haley, Alter, Galit, Dechanet-Merville, Julie, Jost, Stephanie, Carrington, Mary, Altfeld, Marcus

“…The activating NK cell receptor KIR3DS1 has been linked to the outcome of various human diseases, yet a ligand that would account for its biological effects…”
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Immunogenetics of Spontaneous Control of HIV by Carrington, Mary, Walker, Bruce D

“…Host genetic variation is presently estimated to account for about one-fourth of the observed differences in control of HIV across infected individuals…”
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Role of HLA-DP Expression in Graft-Versus-Host Disease After Unrelated Donor Transplantation by Petersdorf, Effie W, Bengtsson, Mats, De Santis, Dianne, Dubois, Valerie, Fleischhauer, Katharina, Gooley, Ted, Horowitz, Mary, Madrigal, J Alejandro, Malkki, Mari, McKallor, Caroline, Morishima, Yasuo, Oudshoorn, Machteld, Spellman, Stephen R, Villard, Jean, Stevenson, Phil, Carrington, Mary

“…The main aim of this study was to evaluate the significance of HLA-DPB1 expression in acute graft-versus-host disease (GVHD) after hematopoietic cell…”
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The Yin and Yang of HLA and KIR in human disease by Kulkarni, Smita, Martin, Maureen P, Carrington, Mary

“…Abstract Killer cell immunoglobulin-like receptors ( KIR ) are expressed on natural killer (NK) cells and subsets of T cells. The KIR genes are polymorphic and…”
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Genetic variation in IL28B and spontaneous clearance of hepatitis C virus by Ge, Dongliang, Alexander, Graeme, Rosen, Hugo R, Tobler, Leslie H, Goldstein, David B, McHutchison, John G, Goedert, James J, Thio, Chloe L, Busch, Michael P, Qi, Ying, O'hUigin, Colm, Kidd, Judith, Kidd, Kenneth, Khakoo, Salim I, Donfield, Sharyne M, Martin, Maureen P, Carrington, Mary, Thomas, David L, Kirk, Gregory D

“…Hepatitis C virus (HCV) infection is the most common blood-borne infection in the United States, with estimates of 4 million HCV-infected individuals in the…”
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Effects of plant species and soil history on root morphology, arbuscular mycorrhizal colonization of roots, and biomass in four tallgrass prairie species by Impastato, Charles J., Carrington, Mary E.

“…Although dominant C₄ grasses in tallgrass prairie are highly mycotrophic, for many non-dominant species neither extent of mycorrhizal colonization nor root…”
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IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody by Richardson, Simone I, Lambson, Bronwen E, Crowley, Andrew R, Bashirova, Arman, Scheepers, Cathrine, Garrett, Nigel, Abdool Karim, Salim, Mkhize, Nonhlanhla N, Carrington, Mary, Ackerman, Margaret E, Moore, Penny L, Morris, Lynn

“…Broadly neutralizing antibodies (bNAbs) protect against HIV infection in non-human primates and their efficacy may be enhanced through interaction with Fc…”
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Seed size and recruitment limitation influence seedling establishment in three tallgrass prairie species by Carrington, Mary E

“…A seed size–seed number tradeoff predicts that large numbers of seeds have an establishment advantage under low levels of competition, while large seed size is…”
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Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2 by Hiby, Susan E, Apps, Richard, Sharkey, Andrew M, Farrell, Lydia E, Gardner, Lucy, Mulder, Arend, Claas, Frans H, Walker, James J, Redman, Christopher W, Redman, Christopher C, Morgan, Linda, Tower, Clare, Regan, Lesley, Moore, Gudrun E, Carrington, Mary, Moffett, Ashley

“…Many common disorders of pregnancy are attributed to insufficient invasion of the uterine lining by trophoblast, fetal cells that are the major cell type of…”
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HLA-B leader and survivorship after HLA-mismatched unrelated donor transplantation by Petersdorf, Effie W., Stevenson, Philip, Bengtsson, Mats, De Santis, Dianne, Dubois, Valerie, Gooley, Ted, Horowitz, Mary, Hsu, Katharine, Madrigal, J. Alejandro, Malkki, Mari, McKallor, Caroline, Morishima, Yasuo, Oudshoorn, Machteld, Spellman, Stephen R., Villard, Jean, Carrington, Mary

“…Hematopoietic cell transplantation (HCT) from HLA-mismatched unrelated donors can cure life-threatening blood disorders, but its success is limited by…”
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Structural and regulatory diversity shape HLA-C protein expression levels by Kaur, Gurman, Gras, Stephanie, Mobbs, Jesse I., Vivian, Julian P., Cortes, Adrian, Barber, Thomas, Kuttikkatte, Subita Balaram, Jensen, Lise Torp, Attfield, Kathrine E., Dendrou, Calliope A., Carrington, Mary, McVean, Gil, Purcell, Anthony W., Rossjohn, Jamie, Fugger, Lars

“…Expression of HLA-C varies widely across individuals in an allele-specific manner. This variation in expression can influence efficacy of the immune response,…”
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Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1 by Bosch, Ronald J, Pollard, Richard B, Streeck, Hendrik, Sidhu, Harlyn K, Lifson, Jeffrey D, Lindsay, Robert J, Orellana, Liliana, Chan, Ellen S, Carrington, Mary, Chang, J Judy, Meier, Angela, Mildvan, Donna, Bazner, Suzane, Robbins, Gregory K, Kulkarni, Smita, Alter, Galit, Altfeld, Marcus, Wen, Tom Fang

“…Manifestations of viral infections can differ between women and men, and marked sex differences have been described in the course of HIV-1 disease…”
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Pegylated Interferon Alfa-2a Monotherapy Results in Suppression of HIV Type 1 Replication and Decreased Cell-Associated HIV DNA Integration by Azzoni, Livio, Foulkes, Andrea S., Papasavvas, Emmanouil, Mexas, Angela M., Lynn, Kenneth M., Mounzer, Karam, Tebas, Pablo, Jacobson, Jeffrey M., Frank, Ian, Busch, Michael P., Deeks, Steven G., Carrington, Mary, O'Doherty, Una, Kostman, Jay, Montaner, Luis J.

“…Background. Antiretroviral therapy (ART)-mediated immune reconstitution fails to restore the capacity of the immune system to spontaneously control human…”
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HIV-1 DNA predicts disease progression and post-treatment virological control by Williams, James P, Hurst, Jacob, Stöhr, Wolfgang, Robinson, Nicola, Brown, Helen, Fisher, Martin, Kinloch, Sabine, Cooper, David, Schechter, Mauro, Tambussi, Giuseppe, Fidler, Sarah, Carrington, Mary, Babiker, Abdel, Weber, Jonathan, Koelsch, Kersten K, Kelleher, Anthony D, Phillips, Rodney E, Frater, John

“…In HIV-1 infection, a population of latently infected cells facilitates viral persistence despite antiretroviral therapy (ART). With the aim of identifying…”
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Impact of HLA Allele-KIR Pairs on HIV Clinical Outcome in South Africa by Mori, Masahiko, Leitman, Ellen, Walker, Bruce, Ndung’u, Thumbi, Carrington, Mary, Goulder, Philip

“…Abstract Background HLA class I contributes to HIV immune control through antigen presentation to cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells…”
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