Search Results - "Carriero, Maria Vincenza"

The urokinase-type plasminogen activator and the generation of inhibitors of urokinase activity and signaling by Carriero, Maria Vincenza, Stoppelli, Maria Patrizia

“…Urokinase (uPA) was originally identified in human urine for its ability to catalyse the transformation of plasminogen into its active form, plasmin which…”
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Tumor Associated Neutrophils. Their Role in Tumorigenesis, Metastasis, Prognosis and Therapy by Masucci, Maria Teresa, Minopoli, Michele, Carriero, Maria Vincenza

“…Tumor Associated Neutrophils (TANs) are engaged into the tumor microenvironment by cytokines and chemokines, can be distinguished according to their activation…”
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The Emerging Role of Neutrophil Extracellular Traps (NETs) in Tumor Progression and Metastasis by Masucci, Maria Teresa, Minopoli, Michele, Del Vecchio, Silvana, Carriero, Maria Vincenza

“…Neutrophil Extracellular Traps (NETs) are net-like structures composed of DNA-histone complexes and proteins released by activated neutrophils. In addition to…”
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Involvement of the urokinase-type plasminogen activator receptor in hematopoietic stem cell mobilization by Selleri, Carmine, Montuori, Nunzia, Ricci, Patrizia, Visconte, Valeria, Carriero, Maria Vincenza, Sidenius, Nicolai, Serio, Bianca, Blasi, Francesco, Rotoli, Bruno, Rossi, Guido, Ragno, Pia

“…We investigated the involvement of the urokinase-type plasminogen-activator receptor (uPAR) in granulocyte–colony-stimulating factor (G-CSF)–induced…”
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Regulation of cell migration and invasion by specific modules of uPA: mechanistic insights and specific inhibitors by Carriero, Maria Vincenza, Franco, Paola, Votta, Giuseppina, Longanesi-Cattani, Immacolata, Vento, Maria Teresa, Masucci, Maria Teresa, Mancini, Alessandro, Caputi, Mario, Iaccarino, Ingram, Stoppelli, Maria Patrizia

“…Urokinase (uPA) is a 411 residues serine protease originally identified for its ability to activate plasminogen and generate plasmin, a broad-spectrum matrix-…”
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Role of Microenvironment on the Fate of Disseminating Cancer Stem Cells by Ingangi, Vincenzo, Minopoli, Michele, Ragone, Concetta, Motti, Maria Letizia, Carriero, Maria Vincenza

“…Disseminating Cancer Stem Cells (CSCs) initiate growth in specific niches of the host tissues, the cellular and molecular components of which sustain signaling…”
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Emerging Targeted Therapeutic Strategies to Overcome Imatinib Resistance of Gastrointestinal Stromal Tumors by Masucci, Maria Teresa, Motti, Maria Letizia, Minopoli, Michele, Di Carluccio, Gioconda, Carriero, Maria Vincenza

“…Gastrointestinal stromal tumors (GISTs) are the most common malignant mesenchymal neoplasms of the gastrointestinal tract. The gold standard for the diagnosis…”
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MicroRNAs as Key Players in Melanoma Cell Resistance to MAPK and Immune Checkpoint Inhibitors by Motti, Maria Letizia, Minopoli, Michele, Di Carluccio, Gioconda, Ascierto, Paolo Antonio, Carriero, Maria Vincenza

“…Advances in the use of targeted and immune therapies have revolutionized the clinical management of melanoma patients, prolonging significantly their overall…”
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Neutrophil Extracellular Traps as an Adhesion Substrate for Different Tumor Cells Expressing RGD-Binding Integrins by Monti, Marcello, De Rosa, Viviana, Iommelli, Francesca, Carriero, Maria Vincenza, Terlizzi, Cristina, Camerlingo, Rosa, Belli, Stefania, Fonti, Rosa, Di Minno, Giovanni, Del Vecchio, Silvana

“…Neutrophil extracellular traps (NETs), in addition to their function as a host defense mechanism, play a relevant role in thrombus formation and metastatic…”
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Integrin-dependent cell adhesion to neutrophil extracellular traps through engagement of fibronectin in neutrophil-like cells by Monti, Marcello, Iommelli, Francesca, De Rosa, Viviana, Carriero, Maria Vincenza, Miceli, Roberta, Camerlingo, Rosa, Di Minno, Giovanni, Del Vecchio, Silvana

“…Neutrophil extracellular traps (NETs), originally recognized as a host defense mechanism, were reported to promote thrombosis and metastatic dissemination of…”
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Controversial Role of Kisspeptins/KiSS-1R Signaling System in Tumor Development by Fratangelo, Federica, Carriero, Maria Vincenza, Motti, Maria Letizia

“…was first described as a metastasis suppressor gene in malignant melanoma. encodes a 145 amino-acid residue peptide that is further processed, producing the 54…”
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Upregulated expression of miR-4443 and miR-4488 in drug resistant melanomas promotes migratory and invasive phenotypes through downregulation of intermediate filament nestin by Castaldo, Vittorio, Minopoli, Michele, Di Modugno, Francesca, Sacconi, Andrea, Liguoro, Domenico, Frigerio, Rachele, Ortolano, Arianna, Di Martile, Marta, Gesualdi, Luisa, Madonna, Gabriele, Capone, Mariaelena, Cirombella, Roberto, Catizone, Angiolina, Del Bufalo, Donatella, Vecchione, Andrea, Carriero, Maria Vincenza, Ascierto, Paolo Antonio, Mancini, Rita, Fattore, Luigi, Ciliberto, Gennaro

“…Abstract Background BRAF-mutant melanoma patients benefit from the combinatorial treatments with BRAF and MEK inhibitors. However, acquired drug resistance…”
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Next-Generation Sequencing Approaches for the Identification of Pathognomonic Fusion Transcripts in Sarcomas: The Experience of the Italian ACC Sarcoma Working Group by Racanelli, Dominga, Brenca, Monica, Baldazzi, Davide, Goeman, Frauke, Casini, Beatrice, De Angelis, Biagio, Guercio, Marika, Milano, Giuseppe Maria, Tamborini, Elena, Busico, Adele, Dagrada, Gianpaolo, Garofalo, Cecilia, Caruso, Chiara, Brunello, Antonella, Pignochino, Ymera, Berrino, Enrico, Grignani, Giovanni, Scotlandi, Katia, Parra, Alessandro, Hattinger, Claudia Maria, Ibrahim, Toni, Mercatali, Laura, De Vita, Alessandro, Carriero, Maria Vincenza, Pallocca, Matteo, Loria, Rossella, Covello, Renato, Sbaraglia, Marta, Dei Tos, Angelo Paolo, Falcioni, Rita, Maestro, Roberta

“…This work describes the set-up of a shared platform among the laboratories of the Alleanza Contro il Cancro (ACC) Italian Research Network for the…”
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A Macroscopic Mathematical Model for Cell Migration Assays Using a Real-Time Cell Analysis by Di Costanzo, Ezio, Ingangi, Vincenzo, Angelini, Claudia, Carfora, Maria Francesca, Carriero, Maria Vincenza, Natalini, Roberto

“…Experiments of cell migration and chemotaxis assays have been classically performed in the so-called Boyden Chambers. A recent technology, xCELLigence Real…”
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Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas by Carriero, Maria Vincenza, Bifulco, Katia, Ingangi, Vincenzo, Costantini, Susan, Botti, Giovanni, Ragone, Concetta, Minopoli, Michele, Motti, Maria Letizia, Rea, Domenica, Scognamiglio, Giosuè, Botti, Gerardo, Arra, Claudio, Ciliberto, Gennaro, Pessi, Antonello

“…The development of metastases is a multistep process that requires the activation of physiological and biochemical processes that govern migration, invasion…”
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Cyclization of the urokinase receptor-derived ser-arg-ser-arg-tyr Peptide generates a potent inhibitor of trans-endothelial migration of monocytes by Yousif, Ali Munaim, Minopoli, Michele, Bifulco, Katia, Ingangi, Vincenzo, Di Carluccio, Gioconda, Merlino, Francesco, Motti, Maria Letizia, Grieco, Paolo, Carriero, Maria Vincenza

“…The receptor for the urokinase-type plasminogen activator (uPAR) is a widely recognized master regulator of cell migration and uPAR88-92 is the minimal…”
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Emerging Treatments Targeting the Tumor Microenvironment for Advanced Chondrosarcoma by Ingangi, Vincenzo, De Chiara, Annarosaria, Ferrara, Gerardo, Gallo, Michele, Catapano, Antonio, Fazioli, Flavio, Di Carluccio, Gioconda, Peranzoni, Elisa, Marigo, Ilaria, Carriero, Maria Vincenza, Minopoli, Michele

“…Chondrosarcoma (ChS), a malignant cartilage-producing tumor, is the second most frequently diagnosed osseous sarcoma after osteosarcoma. It represents a very…”
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Genome-wide analysis of copy number alterations led to the characterisation of PDCD10 as oncogene in ovarian cancer by De Marco, Carmela, Zoppoli, Pietro, Rinaldo, Nicola, Morganella, Sandro, Morello, Matteo, Zuccalà, Valeria, Carriero, Maria Vincenza, Malanga, Donatella, Chirillo, Roberta, Bruni, Paola, Malzoni, Carmine, Di Vizio, Dolores, Venturella, Roberta, Zullo, Fulvio, Rizzuto, Antonia, Ceccarelli, Michele, Ciliberto, Gennaro, Viglietto, Giuseppe

“…•We have identified 201 altered chromosomal bands and 3300 altered genes in human ovarian cancer samples.•The gene encoding for PDCD10 was selected for further…”
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Targeting the Formyl Peptide Receptor type 1 to prevent the adhesion of ovarian cancer cells onto mesothelium and subsequent invasion by Minopoli, Michele, Botti, Giovanni, Gigantino, Vincenzo, Ragone, Concetta, Sarno, Sabrina, Motti, Maria Letizia, Scognamiglio, Giosuè, Greggi, Stefano, Scaffa, Cono, Roca, Maria Serena, Stoppelli, Maria Patrizia, Ciliberto, Gennaro, Losito, Nunzia Simona, Carriero, Maria Vincenza

“…The biological behavior of epithelial ovarian cancer (EOC) is unique since EOC cells metastasize early to the peritoneum. Thereby, new anti-target agents…”
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Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells by Ragone, Concetta, Minopoli, Michele, Ingangi, Vincenzo, Botti, Giovanni, Fratangelo, Federica, Pessi, Antonello, Stoppelli, Maria Patrizia, Ascierto, Paolo Antonio, Ciliberto, Gennaro, Motti, Maria Letizia, Carriero, Maria Vincenza

“…Accumulating evidence demonstrates that the Urokinase Receptor (uPAR) regulates tumor cell migration through its assembly in composite regulatory units with…”
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