Search Results - "Carrión, Ángel Manuel"

AMPK Function in Aging Process by Ruiz, Rocío, Pérez-Villegas, Eva María, Manuel Carrión, Ángel

“…Aging involves the progressive deterioration of physiological functions, diminishing the individual's capacity for survival. Indeed, aging is the main risk…”
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Postnatal proteasome inhibition induces neurodegeneration and cognitive deficiencies in adult mice: a new model of neurodevelopment syndrome by Romero-Granados, Rocío, Fontán-Lozano, Ángela, Aguilar-Montilla, Francisco Javier, Carrión, Ángel Manuel

“…Defects in the ubiquitin-proteasome system have been related to aging and the development of neurodegenerative disease, although the effects of deficient…”
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L1 retrotransposition alters the hippocampal genomic landscape enabling memory formation by Bachiller, Sara, del-Pozo-Martín, Yaiza, Carrión, Ángel Manuel

“…Highlights • De novo L1 insertions occur in the adult hippocampus after exploration. • Blocking hippocampal L1 retrotransposition events prevents long-term…”
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Histone H1 poly[ADP]-ribosylation regulates the chromatin alterations required for learning consolidation by Fontán-Lozano, Angela, Suárez-Pereira, Irene, Horrillo, Angélica, del-Pozo-Martín, Yaiza, Hmadcha, Abdelkrim, Carrión, Angel Manuel

“…Memory formation requires changes in gene expression, which are regulated by the activation of transcription factors and by changes in epigenetic factors…”
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HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System by Bachiller, Sara, Roca-Ceballos, María Angustias, García-Domínguez, Irene, Pérez-Villegas, Eva María, Martos-Carmona, David, Pérez-Castro, Miguel Ángel, Real, Luis Miguel, Rosa, José Luis, Tabares, Lucía, Venero, José Luis, Armengol, José Ángel, Carrión, Ángel Manuel, Ruiz, Rocío

“…A missense mutation in HERC1 provokes loss of cerebellar Purkinje cells, tremor, and unstable gait in tambaleante ( tbl ) mice. Recently, we have shown that…”
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Caloric Restriction Increases Learning Consolidation and Facilitates Synaptic Plasticity through Mechanisms Dependent on NR2B Subunits of the NMDA Receptor by Fontan-Lozano, Angela, Saez-Cassanelli, Jose Luis, Inda, Mari Carmen, de los Santos-Arteaga, Mercedes, Sierra-Dominguez, Sergio Antonio, Lopez-Lluch, Guillermo, Delgado-Garcia, Jose Maria, Carrion, Angel Manuel

“…One of the main focal points of aging research is the search for treatments that will prevent or ameliorate the learning and memory deficiencies associated…”
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Molecular Bases of Caloric Restriction Regulation of Neuronal Synaptic Plasticity by Fontán-Lozano, Ángela, López-Lluch, Guillermo, Delgado-García, José María, Navas, Placido, Carrión, Ángel Manuel

“…Aging is associated with the decline of cognitive properties. This situation is magnified when neurodegenerative processes associated with aging appear in…”
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The M-current inhibitor XE991 decreases the stimulation threshold for long-term synaptic plasticity in healthy mice and in models of cognitive disease by Fontán-Lozano, Ángela, Suárez-Pereira, Irene, Delgado-García, José María, Carrión, Ángel Manuel

“…Aging, mental retardation, number of psychiatric and neurological disorders are all associated with learning and memory impairments. As the underlying causes…”
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Lack of DREAM Protein Enhances Learning and Memory and Slows Brain Aging by Fontán-Lozano, Ángela, Romero-Granados, Rocío, del-Pozo-Martín, Yaiza, Suárez-Pereira, Irene, Delgado-García, José María, Penninger, Josef M., Carrión, Ángel Manuel

“…Memory deficits in aging affect millions of people and are often disturbing to those concerned. Dissection of the molecular control of learning and memory is…”
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The A-current modulates learning via NMDA receptors containing the NR2B subunit by Fontán-Lozano, Ángela, Suárez-Pereira, Irene, González-Forero, David, Carrión, Angel Manuel

“…Synaptic plasticity involves short- and long-term events, although the molecular mechanisms that underlie these processes are not fully understood. The…”
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Acquisition, Consolidation, Reconsolidation, and Extinction of Eyelid Conditioning Responses Require De Novo Protein Synthesis by Inda, Mari Carmen, Delgado-Garcia, Jose Maria, Carrion, Angel Manuel

“…Memory, as measured by changes in an animal's behavior some time after learning, is a reflection of many processes. Here, using a trace paradigm, in mice we…”
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Lack of DREAM Protein Enhances Learning and Memory and Slows Brain Aging by Fontán-Lozano, Ángela, Romero-Granados, Rocío, del-Pozo-Martín, Yaiza, Suárez-Pereira, Irene, Delgado-García, José María, Penninger, Josef M., Carrión, Ángel Manuel

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Cholinergic Septo-Hippocampal Innervation Is Required for Trace Eyeblink Classical Conditioning by Fontan-Lozano, Angela, Troncoso, Julieta, Munera, Alejandro, Carrion, Angel Manuel, Delgado-Garcia, Jose Maria

“…We studied the effects of a selective lesion in rats, with 192-IgG-saporin, of the cholinergic neurons located in the medial septum/diagonal band (MSDB)…”
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Molecular Bases of Caloric Restriction Regulation of Neuronal Synaptic Plasticity by Fontán-Lozano, Ángela, López-Lluch, Guillermo, Delgado-García, José María, Navas, Placido, Carrión, Ángel Manuel

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