Search Results - "Carretta, Elizabeth E"
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SPIROMICS Protocol for Multicenter Quantitative Computed Tomography to Phenotype the Lungs
Published in American journal of respiratory and critical care medicine (01-10-2016)“…Multidetector row computed tomography (MDCT) is increasingly taking a central role in identifying subphenotypes within chronic obstructive pulmonary disease…”
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Variability in objective and subjective measures affects baseline values in studies of patients with COPD
Published in PloS one (21-09-2017)“…Understanding the reliability and repeatability of clinical measurements used in the diagnosis, treatment and monitoring of disease progression is of critical…”
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Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)
Published in Journal of translational medicine (27-01-2015)“…Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS) is a multi-center longitudinal, observational study to identify novel phenotypes and…”
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Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort
Published in The lancet respiratory medicine (01-12-2017)“…Increased concentrations of eosinophils in blood and sputum in chronic obstructive pulmonary disease (COPD) have been associated with increased frequency of…”
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Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort
Published in The lancet respiratory medicine (01-08-2017)“…Present treatment strategies to stratify exacerbation risk in patients with chronic obstructive pulmonary disease (COPD) rely on a history of two or more…”
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Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort
Published in Journal of allergy and clinical immunology (01-01-2018)“…[...]we analyzed eosinophil receptor-positivity in the 3 sample types regardless of subject groups (see Fig E2 in this article's Online Repository at…”
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Heterogeneous burden of lung disease in smokers with borderline airflow obstruction
Published in Respiratory research (20-11-2018)“…The identification of smoking-related lung disease in current and former smokers with normal FEV is complex, leading to debate regarding using a ratio of…”
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Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study
Published in Journal of translational medicine (08-01-2014)“…As a part of the longitudinal Chronic Obstructive Pulmonary Disease (COPD) study, Subpopulations and Intermediate Outcome Measures in COPD study (SPIROMICS),…”
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T1881 Detection of Dysplasia in Barrett's Esophagus with Angle-Resolved Low Coherence Interferometry
Published in Gastroenterology (New York, N.Y. 1943) (2009)Get full text
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Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD
Published in PLoS genetics (17-08-2016)“…Implementing precision medicine for complex diseases such as chronic obstructive lung disease (COPD) will require extensive use of biomarkers and an in-depth…”
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Aspirin Use and Respiratory Morbidity in COPD: A Propensity Score-Matched Analysis in Subpopulations and Intermediate Outcome Measures in COPD Study
Published in Chest (01-03-2019)“…Aspirin use in COPD has been associated with reduced all-cause mortality in meta-regression analysis with few equivocal studies. However, the effect of aspirin…”
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Rural Residence and Chronic Obstructive Pulmonary Disease Exacerbations. Analysis of the SPIROMICS Cohort
Published in Annals of the American Thoracic Society (01-07-2018)“…Rural residence is associated with poor outcomes in several chronic diseases. The association between rural residence and chronic obstructive pulmonary disease…”
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Anemia and Adverse Outcomes in a Chronic Obstructive Pulmonary Disease Population with a High Burden of Comorbidities. An Analysis from SPIROMICS
Published in Annals of the American Thoracic Society (01-06-2018)“…Chronic obstructive pulmonary disease (COPD) is a common cause of morbidity and associated with a significant burden of comorbidities. Although anemia is…”
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Alignment of Inhaled Chronic Obstructive Pulmonary Disease Therapies with Published Strategies. Analysis of the Global Initiative for Chronic Obstructive Lung Disease Recommendations in SPIROMICS
Published in Annals of the American Thoracic Society (01-02-2019)“…Despite awareness of chronic obstructive pulmonary disease (COPD) treatment recommendations, uptake is poor. The Subpopulations and Intermediate Outcome…”
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Centrilobular emphysema and coronary artery calcification: mediation analysis in the SPIROMICS cohort
Published in Respiratory research (18-12-2018)“…Chronic obstructive pulmonary disease (COPD) is associated with a two-to-five fold increase in the risk of coronary artery disease independent of shared risk…”
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Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts
Published in American journal of respiratory and critical care medicine (01-01-2020)“…Chronic obstructive pulmonary disease exacerbations are associated with disease progression, higher healthcare cost, and increased mortality. Published…”
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Genome-wide association study of lung function and clinical implication in heavy smokers
Published in BMC medical genetics (01-08-2018)“…The aim of this study is to identify genetic loci associated with post-bronchodilator FEV /FVC and FEV , and develop a multi-gene predictive model for lung…”
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The matrikine acetyl-proline-glycine-proline and clinical features of COPD: findings from SPIROMICS
Published in Respiratory research (12-11-2019)“…Pulmonary and systemic inflammation are central features of chronic obstructive pulmonary disease (COPD). Previous studies have demonstrated relationships…”
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Association of thrombocytosis with COPD morbidity: the SPIROMICS and COPDGene cohorts
Published in Respiratory research (26-01-2018)“…Thrombocytosis has been associated with COPD prevalence and increased all-cause mortality in patients with acute exacerbation of COPD (AECOPD); but whether it…”
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