Search Results - "Carrel, Monique"
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Extracellular K+ rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl−‐dependent and independent mechanisms
Published in The Journal of physiology (01-11-2016)“…Key points High dietary potassium (K+) intake dephosphorylates and inactivates the NaCl cotransporter (NCC) in the renal distal convoluted tubule (DCT). Using…”
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2
Protein Phosphatase 1 Inhibitor-1 Deficiency Reduces Phosphorylation of Renal NaCl Cotransporter and Causes Arterial Hypotension
Published in Journal of the American Society of Nephrology (01-03-2014)“…The thiazide-sensitive NaCl cotransporter (NCC) of the renal distal convoluted tubule (DCT) controls ion homeostasis and arterial BP. Loss-of-function…”
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3
In vivo nuclear translocation of mineralocorticoid and glucocorticoid receptors in rat kidney: differential effect of corticosteroids along the distal tubule
Published in American journal of physiology. Renal physiology (01-12-2010)“…Aldosterone and corticosterone bind to mineralocorticoid (MR) and glucocorticoid receptors (GR), which, upon ligand binding, are thought to translocate to the…”
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4
Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins
Published in American journal of physiology. Renal physiology (01-06-2008)“…Bartter's syndrome represents a group of hereditary salt- and water-losing renal tubulopathies caused by loss-of-function mutations in proteins mediating or…”
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5
Upregulation of apical sodium-chloride cotransporter and basolateral chloride channels is responsible for the maintenance of salt-sensitive hypertension
Published in American journal of physiology. Renal physiology (01-08-2008)“…We investigated which of the NaCl transporters are involved in the maintenance of salt-sensitive hypertension. Milan hypertensive (MHS) rats were studied 3 mo…”
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Loss of sodium chloride co-transporter impairs the outgrowth of the renal distal convoluted tubule during renal development
Published in Nephrology, dialysis, transplantation (01-03-2020)“…Abstract Background Loss-of-function mutations in the sodium chloride (NaCl) co-transporter (NCC) of the renal distal convoluted tubule (DCT) cause Gitelman…”
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7
Specific disruption of calcineurin-signaling in the distal convoluted tubule impacts the transcriptome and proteome, and causes hypomagnesemia and metabolic acidosis
Published in Kidney international (01-10-2021)“…Adverse effects of calcineurin inhibitors (CNI), such as hypertension, hyperkalemia, acidosis, hypomagnesemia and hypercalciuria, have been linked to…”
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8
The mineralocorticoid receptor (MR) regulates ENaC but not NCC in mice with random MR deletion
Published in The FASEB journal (01-04-2016)“…Abstract only The mineralocorticoid receptor (MR) and its ligand aldosterone increase renal sodium reabsorption via regulation of the epithelial Na + channel…”
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9
Extracellular K super(+) rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl super(-)-dependent and independent mechanisms
Published in The Journal of physiology (01-11-2016)“…Key points * High dietary potassium (K super(+)) intake dephosphorylates and inactivates the NaCl cotransporter (NCC) in the renal distal convoluted tubule…”
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Journal Article -
10
Protein phosphatase 1 Inhibitor‐1 deficiency causes hypotension and reduces the phosphorylation of renal NaCl cotransporter (892.18)
Published in The FASEB journal (01-04-2014)“…The thiazide‐sensitive NaCl cotransporter (NCC) of the renal distal convoluted tubule (DCT) controls ion homeostasis and blood pressure (BP). Gain‐of‐function…”
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11
The renal and blood pressure response to low sodium diet in P2X4 receptor knockout mice
Published in Physiological reports (01-10-2018)“…In the kidney, purinergic (P2) receptor‐mediated ATP signaling has been shown to be an important local regulator of epithelial sodium transport. Appropriate…”
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