Search Results - "Carrasco, Talia Fernandez"
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Oncolytic varicella-zoster virus engineered with ORF8 deletion and armed with drug-controllable interleukin-12
Published in Journal for immunotherapy of cancer (25-03-2024)“…BackgroundThe varicella-zoster virus (VZV), belonging to the group of human α-herpesviruses, has yet to be developed as a platform for oncolytic virotherapy,…”
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Journal Article -
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Oncolytic α-herpesvirus and myeloid-tropic cytomegalovirus cooperatively enhance systemic antitumor responses
Published in Molecular therapy (03-01-2024)“…Oncolytic virotherapy aims to activate host antitumor immunity. In responsive tumors, intratumorally injected herpes simplex viruses (HSVs) have been shown to…”
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Journal Article -
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Smoldering oncolysis by foamy virus carrying CD19 as a CAR target escapes CAR T detection by genomic modification
Published in Molecular Therapy: Oncology (19-09-2024)“…Chimeric antigen receptor (CAR) T cells have had limited success against solid tumors. Here, we used an oncolytic foamy virus (oFV) to display a model CAR…”
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Journal Article