Search Results - "Carrascal, Livia"
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Evolution of Experimental Models in the Study of Glioblastoma: Toward Finding Efficient Treatments
Published in Frontiers in oncology (29-01-2021)“…Glioblastoma (GBM) is the most common form of brain tumor characterized by its resistance to conventional therapies, including temozolomide, the most widely…”
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Effects of classical PKC activation on hippocampal neurogenesis and cognitive performance: mechanism of action
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2021)“…Hippocampal neurogenesis has widely been linked to memory and learning performance. New neurons generated from neural stem cells (NSC) within the dentate gyrus…”
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Oxidative Stress as a Potential Mechanism Underlying Membrane Hyperexcitability in Neurodegenerative Diseases
Published in Antioxidants (01-08-2022)“…Neurodegenerative diseases are characterized by gradually progressive, selective loss of anatomically or physiologically related neuronal systems that produce…”
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Acute Colon Inflammation Triggers Primary Motor Cortex Glial Activation, Neuroinflammation, Neuronal Hyperexcitability, and Motor Coordination Deficits
Published in International journal of molecular sciences (11-05-2022)“…Neuroinflammation underlies neurodegenerative diseases. Herein, we test whether acute colon inflammation activates microglia and astrocytes, induces…”
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A novel PKC activating molecule promotes neuroblast differentiation and delivery of newborn neurons in brain injuries
Published in Cell death & disease (22-04-2020)“…Neural stem cells are activated within neurogenic niches in response to brain injuries. This results in the production of neuroblasts, which unsuccessfully…”
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Migratory Response of Cells in Neurogenic Niches to Neuronal Death: The Onset of Harmonic Repair?
Published in International journal of molecular sciences (01-04-2023)“…Harmonic mechanisms orchestrate neurogenesis in the healthy brain within specific neurogenic niches, which generate neurons from neural stem cells as a…”
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Refinement of Active and Passive Membrane Properties of Layer V Pyramidal Neurons in Rat Primary Motor Cortex During Postnatal Development
Published in Frontiers in molecular neuroscience (01-12-2021)“…Achieving the distinctive complex behaviors of adult mammals requires the development of a great variety of specialized neural circuits. Although the…”
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EFFECT OF LONG-TERM DAILY EXERCISE TRAINING ON THE ELECTROPHYSIOLOGICAL PROPERTIES OF MOTOR CORTEX NEURONS IN A MURINE MODEL OF AGING
Published in IBRO neuroscience reports (01-10-2023)Get full text
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INCREASE IN NEURAL EXCITABILITY IN MOTOR CORTEX NEURONS OF A MURINE MODEL OF NEUROPATHOLOGICAL AGING
Published in IBRO neuroscience reports (01-10-2023)Get full text
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NEWLY GENERATED NEURONS IN MECHANICAL CORTICAL BRAIN INJURIES: A STUDY OF FUNCTIONAL INTEGRATION
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Targeting Protein Kinase C in Glioblastoma Treatment
Published in Biomedicines (04-04-2021)“…Glioblastoma (GBM) is the most frequent and aggressive primary brain tumor and is associated with a poor prognosis. Despite the use of combined treatment…”
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Age-Dependent Vulnerability to Oxidative Stress of Postnatal Rat Pyramidal Motor Cortex Neurons
Published in Antioxidants (19-12-2020)“…Oxidative stress is one of the main proposed mechanisms involved in neuronal degeneration. To evaluate the consequences of oxidative stress on motor cortex…”
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Diminution of voltage threshold plays a key role in determining recruitment of oculomotor nucleus motoneurons during postnatal development
Published in PloS one (09-12-2011)“…The size principle dictates the orderly recruitment of motoneurons (Mns). This principle assumes that Mns of different sizes have a similar voltage threshold,…”
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Changes during the postnatal development in physiological and anatomical characteristics of rat motoneurons studied in vitro
Published in Brain Research Reviews (01-09-2005)“…The postnatal maturation of rat brainstem (oculomotor and hypoglossal nuclei) and spinal motoneurons, based on data collected from in vitro studies, is…”
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Modulation of the input–output function by GABAA receptor‐mediated currents in rat oculomotor nucleus motoneurons
Published in The Journal of physiology (15-11-2014)“…Key points This study deals with synaptic mechanisms involved in the modulation of recruitment threshold and firing rate in ocular motoneurons. In particular,…”
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Modulation of the input–output function by GABA A receptor‐mediated currents in rat oculomotor nucleus motoneurons
Published in The Journal of physiology (15-11-2014)“…Key points This study deals with synaptic mechanisms involved in the modulation of recruitment threshold and firing rate in ocular motoneurons. In particular,…”
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Modulation of the input-output function by GABA sub(A) receptor-mediated currents in rat oculomotor nucleus motoneurons
Published in The Journal of physiology (01-11-2014)“…Key points * This study deals with synaptic mechanisms involved in the modulation of recruitment threshold and firing rate in ocular motoneurons. In…”
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Vitamin D deficiency as a potential risk factor for accelerated aging, impaired hippocampal neurogenesis and cognitive decline: a role for Wnt/β-catenin signaling
Published in Aging (Albany, NY.) (17-06-2020)“…Vitamin D is an essential fat-soluble vitamin that participates in several homeostatic functions in mammalian organisms. Lower levels of vitamin D are produced…”
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Glutamate modulates the firing rate in oculomotor nucleus motoneurons as a function of the recruitment threshold current
Published in The Journal of physiology (01-07-2012)“…Key points • This study deals with the cellular mechanisms involved in firing rate modulation in vivo in the oculomotor system where there are requirements…”
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Muscarinic Modulation of Recruitment Threshold and Firing Rate in Rat Oculomotor Nucleus Motoneurons
Published in Journal of neurophysiology (01-01-2009)“…Department of Physiology and Zoology, University of Seville, Seville, Spain Submitted 6 February 2008; accepted in final form 21 October 2008 Above recruitment…”
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