Search Results - "Carracedo, A"

The PTEN-PI3K pathway: of feedbacks and cross-talks by Carracedo, A, Pandolfi, P P

“…The tumor suppressor PTEN was originally identified as a negative regulator of the phosphoinositide 3-kinase (PI3K) signaling, a main regulator of cell growth,…”
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Signatures of a jet cocoon in early spectra of a supernova associated with a γ-ray burst by Izzo, L., de Ugarte Postigo, A., Maeda, K., Thöne, C. C., Kann, D. A., Della Valle, M., Sagues Carracedo, A., Michałowski, M. J., Schady, P., Schmidl, S., Selsing, J., Starling, R. L. C., Suzuki, A., Bensch, K., Bolmer, J., Campana, S., Cano, Z., Covino, S., Fynbo, J. P. U., Hartmann, D. H., Heintz, K. E., Hjorth, J., Japelj, J., Kamiński, K., Kaper, L., Kouveliotou, C., Krużyński, M., Kwiatkowski, T., Leloudas, G., Levan, A. J., Malesani, D. B., Michałowski, T., Piranomonte, S., Pugliese, G., Rossi, A., Sánchez-Ramírez, R., Schulze, S., Steeghs, D., Tanvir, N. R., Ulaczyk, K., Vergani, S. D., Wiersema, K.

“…Long γ-ray bursts are associated with energetic, broad-lined, stripped-envelope supernovae 1 , 2 and as such mark the death of massive stars. The scarcity of…”
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Detectability of kilonovae in optical surveys: post-mortem examination of the LVC O3 run follow-up by Sagués Carracedo, A, Bulla, M, Feindt, U, Goobar, A

“…ABSTRACT The detection of the binary neutron star (BNS) merger GW170817 and the associated electromagnetic (EM) counterpart, the ‘kilonova’ (kN) AT2017gfo,…”
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Constraining the Observer Angle of the Kilonova AT2017gfo Associated with GW170817: Implications for the Hubble Constant by Dhawan, S., Bulla, M., Goobar, A., Sagués Carracedo, A., Setzer, C. N.

“…There is a strong degeneracy between the luminosity distance (DL) and the observer viewing angle (θobs; hereafter viewing angle) of the gravitational wave (GW)…”
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Spectroscopy of the first resolved strongly lensed Type Ia supernova iPTF16geu by Johansson, J, Goobar, A, Price, S H, Carracedo, A Sagués, Bruna, L Della, Nugent, P E, Dhawan, S, Mörtsell, E, Papadogiannakis, S, Amanullah, R, Goldstein, D, Cenko, S B, De, K, Dugas, A, Kasliwal, M M, Kulkarni, S R, Lunnan, R

“…We report the results from spectroscopic observations of the multiple images of the strongly lensed Type Ia supernova (SN Ia), iPTF16geu, obtained with…”
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eQTL colocalization analysis highlights novel susceptibility genes in Autism Spectrum Disorders (ASD) by Dominguez-Alonso, S., Carracedo, A., Rodriguez-Fontenla, C.

“…Autism Spectrum Disorders (ASD) are a group of neurodevelopmental disorders (NDDs) characterized by difficulties in social interaction and communication,…”
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Unraveling the three-dimensional (3D) genome architecture in Neurodevelopmental Disorders (NDDs) by Carballo-Pacoret, P., Carracedo, A., Rodriguez-Fontenla, C.

“…The human genome, comprising millions of pairs of bases, serves as the blueprint of life, encoding instructions for cellular processes. However, genomes are…”
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How is COVID-19 affecting patients with obsessive–compulsive disorder? A longitudinal study on the initial phase of the pandemic in a Spanish cohort by Alonso, P., Bertolín, S., Segalàs, J., Tubío-Fungueiriño, M., Real, E., Mar-Barrutia, L., Fernández-Prieto, M., Carvalho, S., Carracedo, A., Menchón, JM

“…Abstract Background Although the consequences of the COVID-19 pandemic on emotional health are evident, little is known about its impact on patients with…”
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The non-coding genome in Autism Spectrum Disorders by Dominguez-Alonso, S., Carracedo, A., Rodriguez-Fontenla, C.

“…Autism Spectrum Disorders (ASD) are a group of neurodevelopmental disorders (NDDs) characterized by difficulties in social interaction and communication,…”
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Building a custom large-scale panel of novel microhaplotypes for forensic identification using MiSeq and Ion S5 massively parallel sequencing systems by de la Puente, M., Phillips, C., Xavier, C., Amigo, J., Carracedo, A., Parson, W., Lareu, M.V.

“…[Display omitted] •107 autosomal and 11 X chromosome novel, highly polymorphic microhaplotypes compiled.•A single FFPE Ampliseq panel validated on Ion S5 and…”
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Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression by Erice, O., Labiano, I., Arbelaiz, A., Santos-Laso, A., Munoz-Garrido, P., Jimenez-Agüero, R., Olaizola, P., Caro-Maldonado, A., Martín-Martín, N., Carracedo, A., Lozano, E., Marin, J.J., O'Rourke, C.J., Andersen, J.B., Llop, J., Gómez-Vallejo, V., Padro, D., Martin, A., Marzioni, M., Adorini, L., Trauner, M., Bujanda, L., Perugorria, M.J., Banales, J.M.

“…Cholangiocarcinoma (CCA) is an aggressive tumor type affecting cholangiocytes. CCAs frequently arise under certain cholestatic liver conditions. Intrahepatic…”
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Exome sequencing of early-onset patients supports genetic heterogeneity in colorectal cancer by Fernández-Rozadilla, C., Álvarez-Barona, M., Quintana, I., López-Novo, A., Amigo, J., Cameselle-Teijeiro, J. M., Roman, E., Gonzalez, D., Llor, X., Bujanda, L., Bessa, X., Jover, R., Balaguer, F., Castells, A., Castellví-Bel, S., Capellá, G., Carracedo, A., Valle, L., Ruiz-Ponte, Clara

“…Colorectal cancer (CRC) is a complex disease that can be caused by a spectrum of genetic variants ranging from low to high penetrance changes, that interact…”
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Exploring the biological role of postzygotic and germinal de novo mutations in ASD by Alonso-Gonzalez, A., Calaza, M., Amigo, J., González-Peñas, J., Martínez-Regueiro, R., Fernández-Prieto, M., Parellada, M., Arango, C., Rodriguez-Fontenla, Cristina, Carracedo, A.

“…De novo mutations (DNMs), including germinal and postzygotic mutations (PZMs), are a strong source of causality for Autism Spectrum Disorder (ASD). However,…”
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Phylogeographic analysis points toward invasion of the Timanfaya National Park (Lanzarote; Canary Islands) by a translocated native plant (Rumex lunaria) by González Carracedo, Mario A., Hernández Ferrer, Mariano, Cabrera, Raimundo, Bernardos, María, Pérez Pérez, José A.

“…Rumex lunaria is an endemic shrub of the Canary Islands, which is colonizing the Timanfaya National Park (TNP) in Lanzarote. Whether the arrival of R. lunaria…”
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PiS and PiZ Alleles of SERPINA1 Gene Are Associated With Specific Variants of a BRD4‐Independent Enhancer by Escuela-Escobar, Ainhoa, Herrera-Luis, Esther, Martín-González, Elena, Hernández-Pérez, José María, González Carracedo, Mario A., Pérez, José Antonio Pérez

“…Alpha‐1 antitrypsin deficiency (AATD) is a genetic disorder caused by specific variants in the SERPINA1 gene, which encodes AAT. The most common…”
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Psychiatric polygenic risk as a predictor of COVID-19 risk and severity: insight into the genetic overlap between schizophrenia and COVID-19 by Alemany-Navarro, M., Diz-de Almeida, S., Cruz, R., Riancho, J. A., Rojas-Martínez, A., Lapunzina, P., Flores, C., Carracedo, A.

“…Despite the high contagion and mortality rates that have accompanied the coronavirus disease-19 (COVID-19) pandemic, the clinical presentation of the syndrome…”
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Neuropsychological performance and predictors of pharmacological treatment response in obsessive compulsive disorder by Tubío-Fungueiriño, M., Alemany-Navarro, M., Alonso, P., Arrojo, M., Real, E., Bertolin, S., Menchón, J.M., Carracedo, A., Fernández-Prieto, M., Segalàs, C.

“…Obsessive Compulsive Disorder (OCD) is characterized by the presence of executive dysfunctions. As organizational strategies may play an important role as a…”
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Cognitive and clinical predictors of a long-term course in obsessive compulsive disorder: A machine learning approach in a prospective cohort study by Segalàs, C., Cernadas, E., Puialto, M., Fernández-Delgado, M., Arrojo, M., Bertolin, S., Real, E., Menchón, J.M., Carracedo, A., Tubío-Fungueiriño, M., Alonso, P., Fernández-Prieto, M.

“…Obsessive compulsive disorder (OCD) is a disabling illness with a chronic course, yet data on long-term outcomes are scarce. This study aimed to examine the…”
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Education and training for the judiciary: The Spanish initiative by Prieto, L., Alonso, A., Carracedo, A.

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Publication of population data of human polymorphisms by Lincoln, P, Carracedo, A

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