Search Results - "Carr, Siobhan"

Childhood bronchiectasis, so little is known by Carr, Siobhán B, Unger, Stefan A

“…Correspondence to Professor Siobhán B Carr, Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield Hospitals, London, UK;…”
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De Novo Mutations in FOXJ1 Result in a Motile Ciliopathy with Hydrocephalus and Randomization of Left/Right Body Asymmetry by Wallmeier, Julia, Frank, Diana, Shoemark, Amelia, Nöthe-Menchen, Tabea, Cindric, Sandra, Olbrich, Heike, Loges, Niki T., Aprea, Isabella, Dougherty, Gerard W., Pennekamp, Petra, Kaiser, Thomas, Mitchison, Hannah M., Hogg, Claire, Carr, Siobhán B., Zariwala, Maimoona A., Ferkol, Thomas, Leigh, Margaret W., Davis, Stephanie D., Atkinson, Jeffrey, Dutcher, Susan K., Knowles, Michael R., Thiele, Holger, Altmüller, Janine, Krenz, Henrike, Wöste, Marius, Brentrup, Angela, Ahrens, Frank, Vogelberg, Christian, Morris-Rosendahl, Deborah J., Omran, Heymut

“…Hydrocephalus is one of the most prevalent form of developmental central nervous system (CNS) malformations. Cerebrospinal fluid (CSF) flow depends on both…”
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Eradication success for non-tuberculous mycobacteria in children with cystic fibrosis by Hughes, Dominic A, Bokobza, Idan, Carr, Siobhán B

“…Non-tuberculous mycobacteria (NTM) are an emerging pathogen worldwide in both cystic fibrosis (CF) and non-CF pulmonary disease (PD), with reports suggesting…”
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Treatment Preference Among People With Cystic Fibrosis: The Importance of Reducing Treatment Burden by Cameron, Rory A, Office, Daniel, Matthews, Jessie, Rowley, Mark, Abbott, Janice, Simmonds, Nicholas J, Whitty, Jennifer A, Carr, Siobhán B

“…There is a growing consensus that the perspective of the patient should be considered in the evaluation of novel interventions. What treatment outcomes matter…”
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Data Resource Profile: The UK Cystic Fibrosis Registry by Taylor-Robinson, David, Archangelidi, Olia, Carr, Siobhán B, Cosgriff, Rebecca, Gunn, Elaine, Keogh, Ruth H, MacDougall, Amy, Newsome, Simon, Schlüter, Daniela K, Stanojevic, Sanja, Bilton, Diana

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Chronicity Counts: The Impact of Pseudomonas aeruginosa , Staphylococcus aureus , and Coinfection in Cystic Fibrosis by Mossop, Micaela, Ish-Horowicz, Jonathan, Hughes, Dominic, Dobra, Rebecca, Cunanan, Alessandra G, Rosenthal, Mark, Carr, Siobhán B, Ramadan, Newara, Nolan, Laura M, Davies, Jane C

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Lung Clearance Index at 4 Years Predicts Subsequent Lung Function in Children with Cystic Fibrosis by AURORA, Paul, STANOJEVIC, Sanja, STOCKS, Janet, WADE, Angie, OLIVER, Cara, KOZLOWSKA, Wanda, LUM, Sooky, BUSH, Andrew, PRICE, John, CARR, Siobhán B, SHANKAR, Anu

“…The markedly improved life expectancy of children with cystic fibrosis (CF) has created a new challenge, as traditional markers of lung disease are frequently…”
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Incidence and risk factors of cancer in individuals with cystic fibrosis in the UK; a case-control study by Archangelidi, Olga, Cullinan, Paul, Simmonds, Nicholas J., Mentzakis, Emmanouil, Peckham, Daniel, Bilton, Diana, Carr, Siobhán B.

“…•What is the key question? Which are the most common cancers in the UK cystic fibrosis population and what factors are associated with the incidence of all…”
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Future therapies for cystic fibrosis by Allen, Lucy, Allen, Lorna, Carr, Siobhan B., Davies, Gwyneth, Downey, Damian, Egan, Marie, Forton, Julian T., Gray, Robert, Haworth, Charles, Horsley, Alexander, Smyth, Alan R., Southern, Kevin W., Davies, Jane C.

“…We are currently witnessing transformative change for people with cystic fibrosis with the introduction of small molecule, mutation-specific drugs capable of…”
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Topological data analysis reveals genotype-phenotype relationships in primary ciliary dyskinesia by Shoemark, Amelia, Rubbo, Bruna, Legendre, Marie, Fassad, Mahmood R, Haarman, Eric G, Best, Sunayna, Bon, Irma C M, Brandsma, Joost, Burgel, Pierre-Regis, Carlsson, Gunnar, Carr, Siobhan B, Carroll, Mary, Edwards, Matt, Escudier, Estelle, Honoré, Isabelle, Hunt, David, Jouvion, Gregory, Loebinger, Michel R, Maitre, Bernard, Morris-Rosendahl, Deborah, Papon, Jean-Francois, Parsons, Camille M, Patel, Mitali P, Thomas, Simon N, Thouvenin, Guillaume, Walker, Woolf T, Wilson, Robert, Hogg, Claire, Mitchison, Hannah M, Lucas, Jane S

“…Primary ciliary dyskinesia (PCD) is a heterogeneous inherited disorder caused by mutations in approximately 50 cilia-related genes. PCD genotype-phenotype…”
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Survival estimates in European cystic fibrosis patients and the impact of socioeconomic factors: a retrospective registry Cohort study by McKone, Edward F, Ariti, Cono, Jackson, Abaigeal, Zolin, Anna, Carr, Siobhán B, Orenti, Annalisa, van Rens, Jacqui, Lemonnier, Lydie, Macek, Jr, Milan, Keogh, Ruth H, Naehrlich, Lutz

“…Median survival for cystic fibrosis (CF) patients in Europe is unknown and is likely to be influenced by socioeconomic factors. Using the European Cystic…”
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Using Negative Control Outcomes and Difference-in-Differences Analysis to Estimate Treatment Effects in an Entirely Treated Cohort: The Effect of Ivacaftor in Cystic Fibrosis by Newsome, Simon J, Daniel, Rhian M, Carr, Siobhán B, Bilton, Diana, Keogh, Ruth H

“…Abstract When an entire cohort of patients receives a treatment, it is difficult to estimate the treatment effect in the treated because there are no directly…”
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Are inhaled corticosteroids prescribed rationally in primary ciliary dyskinesia? by Dehlink, Eleonora, Richardson, Charlotte, Marsh, Gemma, Lee, Kiralie, Jamalzadeh, Angela, Bush, Andrew, Hogg, Claire, Carr, Siobhán B

“…Primary ciliary dyskinesia (PCD) is a chronic suppurative lung disease characterised by abnormal mucociliary clearance due to genetic defects of motile cilia…”
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Recovery of baseline lung function after pulmonary exacerbation in children with primary ciliary dyskinesia by Sunther, Meera, Bush, Andrew, Hogg, Claire, McCann, Lauren, Carr, Siobhán B.

“…Summary Rationale Spirometry in children with cystic fibrosis (CF) frequently fails to return to baseline after treatment for a pulmonary exacerbation. It is…”
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An observational study of the lung clearance index throughout childhood in cystic fibrosis: early years matter by Davies, Gwyneth, Stanojevic, Sanja, Raywood, Emma, Duncan, Julie A, Stocks, Janet, Lum, Sooky, Bush, Andrew, Viviani, Laura, Wade, Angie, Calder, Alistair, Owens, Catherine M, Goubau, Christophe, Carr, Siobhán B, Bossley, Cara J, Pao, Caroline, Aurora, Paul

“…The London Cystic Fibrosis Collaboration (LCFC) has prospectively followed a clinically diagnosed cohort of infants with cystic fibrosis (CF) born in South…”
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Projecting the impact of triple CFTR modulator therapy on intravenous antibiotic requirements in cystic fibrosis using patient registry data combined with treatment effects from randomised trials by Keogh, Ruth H, Cosgriff, Rebecca, Andrinopoulou, Eleni-Rosalina, Brownlee, Keith G, Carr, Siobhán B, Diaz-Ordaz, Karla, Granger, Emily, Jewell, Nicholas P, Lewin, Alex, Leyrat, Clemence, Schlüter, Daniela K, van Smeden, Maarten, Szczesniak, Rhonda D, Connett, Gary J

“…Cystic fibrosis (CF) is a life-threatening genetic disease, affecting around 10 500 people in the UK. Precision medicines have been developed to treat specific…”
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Non-invasive ventilation and clinical outcomes in cystic fibrosis: Findings from the UK CF registry by Archangelidi, Olga, Carr, Siobhán B, Simmonds, Nicholas J, Bilton, Diana, Banya, Winston, Cullinan, Paul

“…AbstractBackgroundNon-invasive ventilation (NIV) for respiratory failure and airway clearance is an established intervention in cystic fibrosis (CF), but its…”
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Clinical characteristics of SARS-CoV-2 infection in children with cystic fibrosis: An international observational study by Bain, Robert, Cosgriff, Rebecca, Zampoli, Marco, Elbert, Alexander, Burgel, Pierre-Régis, Carr, Siobhán B, Castaños, Claudio, Colombo, Carla, Corvol, Harriet, Faro, Albert, Goss, Christopher H, Gutierrez, Hector, Jung, Andreas, Kashirskaya, Nataliya, Marshall, Bruce C, Melo, Joel, Mondejar-Lopez, Pedro, de Monestrol, Isabelle, Naehrlich, Lutz, Padoan, Rita, Pastor-Vivero, Maria Dolores, Rizvi, Samar, Salvatore, Marco, Filho, Luiz Vicente Ribeiro Ferreira da Silva, Brownlee, Keith G, Haq, Iram J, Brodlie, Malcolm

“…The presence of co-morbidities, including underlying respiratory problems, has been identified as a risk factor for severe COVID-19 disease. Information on the…”
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Impact of cystic fibrosis on birthweight: a population based study of children in Denmark and Wales by Schlüter, Daniela K, Griffiths, Rowena, Adam, Abdulfatah, Akbari, Ashley, Heaven, Martin L, Paranjothy, Shantini, Nybo Andersen, Anne-Marie, Carr, Siobhán B, Pressler, Tania, Diggle, Peter J, Taylor-Robinson, David

“…Poor growth during infancy and childhood is a characteristic feature of cystic fibrosis (CF). However, the impact of CF on intrauterine growth is unclear. We…”
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Combination antifungal therapy for Scedosporium species in cystic fibrosis by Bentley, Siân, Davies, Jane C., Carr, Siobhán B., Balfour‐Lynn, Ian M.

“…Objective To evaluate safety and efficacy of oral posaconazole and terbinafine for Lomentospora prolificans and Scedosporium apiospermum in children with…”
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