Search Results - "Carr, S B"

Lung Clearance Index and HRCT are complementary markers of lung abnormalities in young children with CF by Owens, C M, Aurora, P, Stanojevic, S, Bush, A, Wade, A, Oliver, C, Calder, A, Price, J, Carr, S B, Shankar, A, Stocks, Janet

“…High resolution computed tomography (HRCT) is a more sensitive tool for detecting early cystic fibrosis (CF) lung disease than either spirometry or plain…”
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Impact of elexacaftor/tezacaftor/ivacaftor on fat-soluble vitamin levels in children with cystic fibrosis by Schembri, L, Warraich, S, Bentley, S, Carr, S B, Balfour-Lynn, I M

“…Children with cystic fibrosis are at risk of fat-soluble vitamin deficiency. CFTR modulators positively effect nutritional status. This study aimed to assess…”
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Diagnosis of cystic fibrosis in London and South East England before and after the introduction of newborn screening by Lim, MTC, Wallis, C, Price, J F, Carr, S B, Chavasse, R J, Shankar, A, Seddon, P, Balfour-Lynn, I M

“…Introduction Newborn screening (NBS) for cystic fibrosis (CF) was introduced to London and South East England in 2007. We wished to assess the details of…”
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Pregnancy rates and outcomes in women with cystic fibrosis in the UK: comparisons with the general population before and after the introduction of disease‐modifying treatment, 2003–17 by Esan, OB, Schlüter, DK, Phillips, R, Cosgriff, R, Paranjothy, S, Williams, D, Norman, R, Carr, SB, Duckers, J, Taylor‐Robinson, D

“…Objective To compare pregnancy rates and outcomes for women with cystic fibrosis in the UK with those of the general population and assess the effect of the…”
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Extrahepatic metastases of hepatocellular carcinoma by Katyal, S, Oliver, 3rd, J H, Peterson, M S, Ferris, J V, Carr, B S, Baron, R L

“…To determine the relative frequency, incidence, and locations of metastases of hepatocellular carcinoma (HCC), correlate extrahepatic metastatic disease with…”
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ECFS standards of care on CFTR-related disorders: Towards a comprehensive program for affected individuals by De Wachter, E, De Boeck, K, Sermet-Gaudelus, I, Simmonds, NJ, Munck, A, Naehrlich, L, Barben, J, Boyd, C, Veen, SJ, Carr, SB, Fajac, I, Farrell, PM, Girodon, E, Gonska, T, Grody, WW, Jain, M, Jung, A, Kerem, E, Raraigh, KS, van Koningsbruggen-Rietschel, S, Waller, MD, Southern, KW, Castellani, C

“…•Advantages and challenges of a dedicated patient registry for people with CFTR-RD.•The CFTR-RD risk for infants with a CRMS/CFSPID designation.•Peculiarities…”
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Clinical Immunology Review Series: An approach to the management of pulmonary disease in primary antibody deficiency by Tarzi, M.D, Grigoriadou, S, Carr, S.B, Kuitert, L.M, Longhurst, H.J

“…The sinopulmonary tract is the major site of infection in patients with primary antibody deficiency syndromes, and structural lung damage arising from repeated…”
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Growth in children with cystic fibrosis-related diabetes by Cheung, M.S., Bridges, N.A., Prasad, S.A., Francis, J., Carr, S.B., Suri, R., Balfour-Lynn, I.M.

“…Cystic fibrosis‐related diabetes (CFRD) is associated with a shortened life expectancy and greater deterioration in lung function than in CF patients with…”
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Restoration of exocrine pancreatic function in older children with cystic fibrosis on ivacaftor by Nichols, A.L., Davies, J.C., Jones, D., Carr, S.B.

“…Prior to the use of cystic fibrosis (CF) modulator therapy, exocrine pancreatic insufficiency in CF was thought to be irreversible. Improvement in pancreatic…”
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Communicating cystic fibrosis newborn screening results to parents by Seddon, L., Dick, K., Carr, S. B., Balfour-Lynn, I. M.

“…The way results of cystic fibrosis (CF) newborn screening are communicated to parents is critical yet is done differently across the globe. We surveyed parents…”
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Airway function in infants newly diagnosed with cystic fibrosis by Ranganathan, SC, Dezateux, C, Bush, A, Carr, SB, Castle, RA, Madge, S, Price, J, Stroobant, J, Wade, A, Wallis, C, Stocks, J

“…The lung function of infants with cystic fibrosis is often reduced shortly after diagnosis. We measured the airway function of newly diagnosed infants to test…”
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Initiating home spirometry for children during the COVID-19 pandemic – A practical guide by Richardson, C.H., Orr, N.J., Ollosson, S.L., Irving, S.J., Balfour-Lynn, I.M., Carr, S.B.

“…The COVID-19 pandemic has led to a rapid escalation in use of home monitoring and video consultations in children with a variety of chronic respiratory…”
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Investigating the effects of long-term dornase alfa use on lung function using registry data by Newsome, S.J., Daniel, R.M., Carr, S.B., Bilton, D., Keogh, R.H.

“…Dornase alfa (DNase) is one of the commonest cystic fibrosis (CF) treatments and is often used for many years. However, studies have not evaluated the…”
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A comparison of the prevalence of urinary incontinence in girls with cystic fibrosis, asthma, and healthy controls by Prasad, S.A., Balfour-Lynn, I.M., Carr, S.B., Madge, S.L.

“…Urinary incontinence (UI) is recognized as a significant problem in adult females with cystic fibrosis and can often have a marked impact on day‐to‐day…”
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Optimising equity of access: how should we allocate slots to the most competitive trials in Cystic Fibrosis (CF)? by Dobra, R., Davies, G., Pike, K., Strassle, C., Allen, L., Brendell, R., Brownlee, K., Carr, S.B., Simmonds, N.J., Davies, J.C.

“…•Securing a place on certain trials can be highly competitive•We were challenged to develop a fair allocation system for slots on such trials•We explore ~200…”
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Early detection of cystic fibrosis lung disease : multiple-breath washout versus raised volume tests by LUM, Sooky, GUSTAFSSON, Per, STROOBANT, John, WADE, Angie, WALLIS, Colin, WYATT, Hilary, STOCKS, Janet, LJUNGBERG, Henrik, HÜLSKAMP, Georg, BUSH, Andrew, CARR, Siobhan B, CASTLE, Rosemary, HOO, Ah-Fong, PRICE, John, RANGANATHAN, Sarath

“…Lung clearance index (LCI), a measure of ventilation inhomogeneity derived from the multiple-breath inert gas washout (MBW) technique, has been shown to detect…”
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Growth and lung function in Asian patients with cystic fibrosis by Callaghan, B D, Hoo, A F, Dinwiddie, R, Balfour-Lynn, I M, Carr, S B

“…Background: The incidence of cystic fibrosis (CF) in Asians is rare. How these patients fare in terms of morbidity and mortality in the UK compared to their…”
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Primary Ciliary Dyskinesia Due to Microtubular Defects is Associated with Worse Lung Clearance Index by Irving, S., Dixon, M., Fassad, M. R., Frost, E., Hayward, J., Kilpin, K., Ollosson, S., Onoufriadis, A., Patel, M. P., Scully, J., Carr, S. B., Mitchison, H. M., Loebinger, M. R., Hogg, C., Shoemark, A., Bush, A.

“…Purpose Primary ciliary dyskinesia (PCD) is characterised by repeated upper and lower respiratory tract infections, neutrophilic airway inflammation and…”
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P012 Preliminary experience of the use of oral posaconazole and terbinafine to treat lomentospora prolificans and scedosporium apiospermum in children with cystic fibrosis by Bentley, Sian, Balfour-Lynn, IM, Carr, SB

“…BackgroundItraconazole and voriconazole are the drugs of choice for Lomentospora prolificans and Scedosporium apiospermum. Posaconazole, is often substituted…”
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Fair selection of participants in clinical trials: The challenge to push the envelope further by Davies, J.C, Scott, S, Dobra, R, Brendell, R, Brownlee, K, Carr, S.B, Cosgriff, R, Simmonds, N.J, Jahan, R, Jones, A, Matthews, J, Brown, S, Galono, K, Miles, K, Pao, C, Shafi, N, Watson, D, Orchard, C, Davies, G, Pike, K, Shah, S, Bossley, C.J, Fong, T, Macedo, P, Ruiz, G, Waller, M, Baker, L

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