Search Results - "Carr, Peter W."
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Two-Dimensional Liquid Chromatography: A State of the Art Tutorial
Published in Analytical chemistry (Washington) (03-01-2017)“…In this tutorial, we discuss the motivations for doing two-dimensional liquid chromatography (2D-LC) and describe the commonly used implementations of the…”
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The chemical interpretation and practice of linear solvation energy relationships in chromatography
Published in Journal of Chromatography A (08-09-2006)“…This review focuses on the use of linear solvation energy relationships (LSERs) to understand the types and relative strength of the chemical interactions that…”
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Fast, comprehensive two-dimensional liquid chromatography
Published in Journal of Chromatography A (19-10-2007)“…The absolute need to improve the separating power of liquid chromatography, especially for multi-constituent biological samples, is becoming increasingly…”
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Separation Speed and Power in Isocratic Liquid Chromatography: Loss in Performance of Poppe vs Knox-Saleem Optimization
Published in Analytical chemistry (Washington) (07-07-2015)“…The best separation possible at a given analysis time and maximum system pressure is achieved by simultaneously optimizing column length, eluent velocity, and…”
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Effect of Pressure, Particle Size, and Time on Optimizing Performance in Liquid Chromatography
Published in Analytical chemistry (Washington) (01-07-2009)“…Although the principles of optimization of high-performance liquid chromatography (HPLC) have a long history starting with the work of Giddings in the 1960s…”
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Fast, Comprehensive Two-Dimensional HPLC Separation of Tryptic Peptides Based on High-Temperature HPLC
Published in Journal of the American Chemical Society (13-04-2005)“…Two-dimensional HPLC (2D-LC) has recently received considerable attention, and is being used as an alternative to 2D gel electrophoresis in proteomics…”
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Peak Capacity Optimization of Peptide Separations in Reversed-Phase Gradient Elution Chromatography: Fixed Column Format
Published in Analytical chemistry (Washington) (15-05-2006)“…The optimization of peak capacity in gradient elution RPLC is essential for the separation of multicomponent samples such as those encountered in proteomic…”
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Role of ion pairing in anionic additive effects on the separation of cationic drugs in reversed-phase liquid chromatography
Published in Journal of Chromatography A (29-04-2005)“…Mobile phase additives can significantly affect the separation of cationic drugs in reversed-phase liquid chromatography (RPLC). Although there are many…”
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Analysis and critical comparison of the reversed-phase and ion-exchange contributions to retention on polybutadiene coated zirconia and octadecyl silane bonded silica phases
Published in Journal of Chromatography A (09-05-2003)“…The two major modes of retention of basic compounds in reversed-phase liquid chromatography on both octadecyl silane bonded silica-based (ODS) and…”
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Development of a carbon clad core-shell silica for high speed two-dimensional liquid chromatography
Published in Journal of Chromatography A (16-03-2012)“…► We developed a carbon stationary phase coated on superficially porous silica (2.7μm). ► The new packing provides the unique chromatographic selectivity of…”
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Application of silica-based hyper-crosslinked sulfonate-modified reversed stationary phases for separating highly hydrophilic basic compounds
Published in Journal of Chromatography A (15-08-2008)“…The separation and determination of hydrophilic basic compounds are of great importance in many fields including clinical and biological research,…”
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The combined effect of silanols and the reversed-phase ligand on the retention of positively charged analytes
Published in Journal of Chromatography A (21-01-2005)“…The nature of the interaction of positively charged analytes with the surface of reversed-phase bonded phases has been investigated as a function of both pH…”
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High-Temperature Ultrafast Liquid Chromatography
Published in Analytical chemistry (Washington) (15-03-2000)“…A novel liquid chromatographic system which enables high temperature ultrafast liquid chromatography (HTUFLC) has been designed through the careful…”
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Perspectives on Recent Advances in the Speed of High-Performance Liquid Chromatography
Published in Analytical chemistry (Washington) (15-03-2011)“…Perhaps the most consistent trend in the development of high-performance liquid chromatography (HPLC) since its inception in the 1960s has been the continuing…”
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Accuracy of Empirical Correlations for Estimating Diffusion Coefficients in Aqueous Organic Mixtures
Published in Analytical chemistry (Washington) (01-07-1997)“…Diffusion coefficients for a homologous series of alkylbenzenes and alkylphenones have been measured by the Aris−Taylor open tube method from 30 to 60 °C over…”
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Comparative study of the linear solvation energy relationship, linear solvent strength theory, and typical-conditions model for retention prediction in reversed-phase liquid chromatography
Published in Journal of Chromatography A (02-08-2002)“…This paper describes two new retention models for predicting retention under different reversed-phase liquid chromatography (RPLC) conditions. The first one is…”
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Journal Article Conference Proceeding -
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Improving Peak Capacity in Fast Online Comprehensive Two-Dimensional Liquid Chromatography with Post-First-Dimension Flow Splitting
Published in Analytical chemistry (Washington) (15-12-2011)“…The use of flow splitters between the two dimensions in online comprehensive two-dimensional (2D) liquid chromatography (LC × LC) has not received very much…”
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Effect of First-Dimension Undersampling on Effective Peak Capacity in Comprehensive Two-Dimensional Separations
Published in Analytical chemistry (Washington) (15-01-2008)“…The objective of this work is to establish a means of correcting the theoretical maximum peak capacity of comprehensive two-dimensional (2D) separations to…”
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Dependence of Thermal Mismatch Broadening on Column Diameter in High-Speed Liquid Chromatography at Elevated Temperatures
Published in Analytical chemistry (Washington) (15-07-2001)“…In this paper, we compare a narrow-bore column (2.1-mm i.d.) to a conventional-bore column (4.6 mm i.d.) at elevated temperatures under conditions where…”
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