Search Results - "Carr, B R"

The Human Placenta Expresses CYP17 and Generates Androgens De Novo by Escobar, J. C, Patel, S. S, Beshay, V. E, Suzuki, T, Carr, B. R

“…CYP17 is expressed by the human placenta leading to de novo androgen and estrogen synthesis by trophoblast tissue. Introduction: The human placenta is believed…”
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Progesterone receptor isoform A but not B is expressed in endometriosis by ATTIA, G. R, ZEITOUN, K, EDWARDS, D, JOHNS, A, CARR, B. R, BULUN, S. E

“…We previously demonstrated that 17beta hydroxysteroid dehydrogenase type 2, the enzyme that inactivates estradiol to estrone, is expressed in luteal eutopic…”
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Liver receptor homologue-1 is expressed in human steroidogenic tissues and activates transcription of genes encoding steroidogenic enzymes by Sirianni, R, Seely, JB, Attia, G, Stocco, DM, Carr, BR, Pezzi, V, Rainey, WE

“…In the current study we test the hypothesis that liver receptor homologue-1 (LRH; designated NR5A2) is involved in the regulation of steroid hormone…”
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Gene profiling of human fetal and adult adrenals by Rainey, WE, Carr, BR, Wang, ZN, Parker CR

“…The mechanisms that lead to the steroidogenic differences in the human fetal adrenal (HFA) and adult adrenal gland are not known. However, gene expression…”
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Treatment of severe postmenopausal endometriosis with an aromatase inhibitor by Takayama, K, Zeitoun, K, Gunby, R T, Sasano, H, Carr, B R, Bulun, S E

“…To treat an unusually aggressive case of recurrent postmenopausal endometriosis. Case report. University of Texas Southwestern Medical Center (Dallas, Texas)…”
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Effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate on plasma lipids and lipoproteins, coagulation factors, and carbohydrate metabolism by Lobo, R A, Bush, T, Carr, B R, Pickar, J H

“…To determine the effects of lower doses of conjugated equine estrogens (CEE) alone or CEE and medroxyprogesterone acetate (MPA) on lipoproteins, carbohydrate…”
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Safety and efficacy of the selective progesterone receptor modulator asoprisnil for heavy menstrual bleeding with uterine fibroids: pooled analysis of two 12-month, placebo-controlled, randomized trials by Stewart, E A, Diamond, M P, Williams, A R W, Carr, B R, Myers, E R, Feldman, R A, Elger, W, Mattia-Goldberg, C, Schwefel, B M, Chwalisz, K

“…Abstract STUDY QUESTION Can asoprisnil, a selective progesterone receptor modulator, provide clinically meaningful improvements in heavy menstrual bleeding…”
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A role for src tyrosine kinase in regulating adrenal aldosterone production by Sirianni, R, Carr, BR, Pezzi, V, Rainey, WE

“…Adrenal aldosterone synthesis is influenced by a variety of factors. The major physiological regulators of aldosterone production are angiotensin II (Ang…”
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An evaluation of the effect of gonadotropin-releasing hormone analogs and medroxyprogesterone acetate on uterine leiomyomata volume by magnetic resonance imaging: a prospective, randomized, double blind, placebo-controlled, crossover trial by Carr, B R, Marshburn, P B, Weatherall, P T, Bradshaw, K D, Breslau, N A, Byrd, W, Roark, M, Steinkampf, M P

“…The purpose of this study was to prospectively compare the effectiveness of administering medroxyprogesterone acetate (MPA; 20 mg/day) in either the first…”
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Regulation of biologically active dimeric inhibin A and B from infancy to adulthood in the male by BYRD, W, BENNETT, M. J, CARR, B. R, DONG, Y, WIANS, F, RAINEY, W

“…Inhibins are glycoprotein members of the transforming growth factor-beta family that have been implicated in the control of spermatogenesis by exerting a…”
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Inhibition of Src tyrosine kinase stimulates adrenal androgen production by Sirianni, R, Carr, BR, Ando, S, Rainey, WE

“…A unique characteristic of the primate adrenal is the ability to produce 19-carbon steroids, often called the adrenal androgens. Although it is clear that the…”
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Evaluation of clomiphene citrate and human chorionic gonadotropin treatment: a prospective, randomized, crossover study during intrauterine insemination cycles by Arici, A, Byrd, W, Bradshaw, K, Kutteh, W H, Marshburn, P, Carr, B R

“…To test the hypothesis that in couples undergoing IUI, actively managed cycles using clomiphene citrate (CC) stimulation, ultrasound monitoring, and hCG timing…”
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Estrogen and progestin components of oral contraceptives: Relationship to vascular disease by Carr, Bruce R., Ory, Howard

“…Recently, new information has been published about: a) the relationship between combination oral contraceptives (OCs), estrogen dose, cigarette smoking, and…”
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Oral contraceptive pills, gonadotropin-releasing hormone agonists, or use in combination for treatment of hirsutism: a clinical research center study by Carr, B R, Breslau, N A, Givens, C, Byrd, W, Barnett-Hamm, C, Marshburn, P B

“…The effectiveness of oral contraceptive pills (OCPs), GnRH agonist (GnRH-a), and a combination of OCPs and GnRH-a in the treatment of hirsute women was…”
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Spermatozoal characteristics from fresh and frozen donor semen and their correlation with fertility outcome after intrauterine insemination by Marshburn, P B, McIntire, D, Carr, B R, Byrd, W

“…To determine if conventional sperm parameters, specific characteristics of sperm motion determined by computer-aided semen analysis (CASA), sperm penetration…”
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A 12-month extension study to evaluate the safety and efficacy of asoprisnil in women with heavy menstrual bleeding and uterine fibroids by Diamond, M P, Stewart, E A, Williams, A R W, Carr, B R, Myers, E R, Feldman, R A, Elger, W, Mattia-Goldberg, C, Schwefel, B M, Chwalisz, K

“…What is the safety and efficacy profile during long-term (12-24 months) uninterrupted treatment with the selective progesterone receptor modulator asoprisnil,…”
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Inhibin and activin differentially regulate androgen production and 17 alpha-hydroxylase expression in human ovarian thecal-like tumor cells by Sawetawan, C, Carr, B R, McGee, E, Bird, I M, Hong, T L, Rainey, W E

“…Activin and inhibin are structurally related dimeric glycoproteins belonging to the transforming growth factor-beta superfamily of proteins which are…”
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Protein kinase C in uterine and systemic arteries during ovarian cycle and pregnancy by Magness, R R, Rosenfeld, C R, Carr, B R

“…Elevated uterine blood flow is associated with increases in local estrogen-to-progesterone ratios during the follicular phase of the ovarian cycle and late…”
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Transformation of human granulosa cells with the E6 and E7 regions of human papillomavirus by Rainey, W H, Sawetawan, C, Shay, J W, Michael, M D, Mathis, J M, Kutteh, W, Byrd, W, Carr, B R

“…Ovarian granulosa cells are the primary site of estrogen and progesterone synthesis and play an essential role in the maturation of the developing ovum…”
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Metformin directly inhibits androgen production in human thecal cells by Attia, G R, Rainey, W E, Carr, B R

“…To examine the direct effect of metformin on thecal cell androgen production. Basic science research laboratory, University of Texas Southwestern, Dallas,…”
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