Search Results - "Carr, A.M"

The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast by Fontebasso, Y., Etheridge, T.J., Oliver, A.W., Murray, J.M., Carr, A.M.

“…•Characterization of FANCD2/FANCI-associated nuclease 1 (Fan1) in the model organism Schizosaccharomyces pombe.•Fan1 is a key component of a previously…”
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Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice by de Klein, A., Muijtjens, M., van Os, R., Verhoeven, Y., Smit, B., Carr, A.M., Lehmann, A.R., Hoeijmakers, J.H.J.

“…Checkpoints of DNA integrity are conserved throughout evolution, as are the kinases ATM (Ataxia Telangiectasia mutated) and ATR (Ataxia- and Rad-related),…”
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Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair by Hartsuiker, E., Vaessen, E., Carr, A.M., Kohli, J.

“…To study the role of Rad50 in the DNA damage response, we cloned and deleted the Schizosaccharo myces pombe RAD50 homologue. The deletion is sensitive to a…”
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DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe by Al-Khodairy, F, Carr, A.M

“…We have tested mutants corresponding to 20 DNA repair genes of the fission yeast Schizosaccharomyces pombe for their ability to arrest in G2 after DNA damage…”
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Versatile shuttle vectors and genomic libraries for use with Schizosaccharomyces pombe by Barbet, N, Muriel, W J, Carr, A M

“…We have constructed a variety of pUC-based vectors designed for maintenance in Schizosaccharomyces pombe. These can be used for both gene bank construction and…”
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Corrigendum to “The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast” [DNA Repair 12 (December (12)) (2013) 1011–1023] by Fontebasso, Y., Etheridge, T.J., Oliver, A.W., Murray, J.M., Carr, A.M.

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rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest by Stewart, E, Chapman, C.R, Al-Khodairy, F, Carr, A.M, Enoch, T

“…In eukaryotic cells, S phase can be reversibly arrested by drugs that inhibit DNA synthesis or DNA damage. Here we show that recovery from such treatments is…”
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Schizosaccharomyces pombe rad3 checkpoint gene by Bentley, N.J, Holtzman, D.A, Flaggs, G, Keegan, K.S, DeMaggio, A, Ford, J.C, Hoekstra, M, Carr, A.M

“…The rad3 gene of Schizosaccharomyces pombe is required for checkpoint pathways that respond to DNA damage and replication blocks. We report the complete rad3…”
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Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses by Martinho, R.G, Lindsay, H.D, Flaggs, G, Demaggio, A.J, Hoekstra, M.F, Carr, A.M, Bentley, N.J

“…Eukaryotic cells respond to DNA damage and S phase replication blocks by arresting cell‐cycle progression through the DNA structure checkpoint pathways. In…”
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Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The “Undoing” of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network by Hu, Shenshen, Offenbacher, Adam R, Thompson, Erin M, Gee, Christine L, Wilcoxen, Jarett, Carr, Cody A. M, Prigozhin, Daniil M, Yang, Vanessa, Alber, Tom, Britt, R. David, Fraser, James S, Klinman, Judith P

“…Soybean lipoxygenase (SLO) has served as a prototype for understanding the molecular origin of enzymatic rate accelerations. The double mutant (DM) L546A/L754A…”
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14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast by Ford, J.C, Al-Khodairy, F, Fotou, E, Sheldrick, K.S, Griffiths, D.J.F, Carr, A.M

“…During the cel cycle, DNA is replicated and segregated equally into two daughter cells. The DNA damage checkpoint ensures that DNA damage is repaired before…”
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Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins by Griffiths, D.J.F, Barbet, N.C, McCready, S, Lehmann, A.R, Carr, A.M

“…Following DNA damage or a block to DNA synthesis, checkpoint pathways act to arrest mitosis and prevent the attempted segregation of damaged or unreplicated…”
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The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair by Lehmann, A. R., Walicka, M., Griffiths, D. J. F., Murray, J. M., Watts, F. Z., McCready, S., Carr, A. M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Schizosaccharomyces pombe hus5 gene encodes a ubiquitin conjugating enzyme required for normal mitosis by Al-Khodairy, F, Enoch, T, Hagan, I.M, Carr, A.M

“…Normal eukaryotic cells do not enter mitosis unless DNA is fully replicated and repaired. Controls called 'checkpoints', mediate cell cycle arrest in response…”
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Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes by Flaggs, G, Plug, A W, Dunks, K M, Mundt, K E, Ford, J C, Quiggle, M R, Taylor, E M, Westphal, C H, Ashley, T, Hoekstra, M F, Carr, A M

“…Checkpoint pathways prevent cell-cycle progression in the event of DNA lesions. Checkpoints are well defined in mitosis, where lesions can be the result of…”
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Hydrogen–Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling by Offenbacher, Adam R, Hu, Shenshen, Poss, Erin M, Carr, Cody A. M, Scouras, Alexander D, Prigozhin, Daniil M, Iavarone, Anthony T, Palla, Ali, Alber, Tom, Fraser, James S, Klinman, Judith P

“…Defining specific pathways for efficient heat transfer from protein–solvent interfaces to their active sites represents one of the compelling and timely…”
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Cloning the RAD51 homologue of Schizosaccharomyces pombe by Muris, D.F.R, Vreeken, K, Carr, A.M, Broughton, B.C, Lehmann, A.R, Lohmann, P.H.M, Pastink, A

“…The RAD51 gene of Saccharomyces cerevisiae encodes a RecA like protein, which is involved in the recombinational repair of double strand breaks. We have…”
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Fission yeast wee1 protein kinase is not required for DNA damage-dependent mitotic arrest by Barbet, N.C, Carr, A.M

“…CHECKPOINTS maintain the dependency relationships between discrete events in the cell cycle (for example, ensuring mitosis does not occur before DNA…”
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Analysis of fission yeast DNA structure checkpoints by Carr, A.M

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New Insights into Development from Mitosis of a Unicellular Yeast by Hagan, I.M., Jones, N., Carr, A.M.

“…Studies in the fission yeast Schizosaccharomyces pombe have uncovered a new spindle checkpoint…”
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