Search Results - "Carpenedo, Richard L."

Derivation and Expansion of PAX7-Positive Muscle Progenitors from Human and Mouse Embryonic Stem Cells by Shelton, Michael, Metz, Jeff, Liu, Jun, Carpenedo, Richard L., Demers, Simon-Pierre, Stanford, William L., Skerjanc, Ilona S.

“…Cell therapies treating pathological muscle atrophy or damage requires an adequate quantity of muscle progenitor cells (MPCs) not currently attainable from…”
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Incorporation of biomaterials in multicellular aggregates modulates pluripotent stem cell differentiation by Bratt-Leal, Andrés M, Carpenedo, Richard L, Ungrin, Mark D, Zandstra, Peter W, McDevitt, Todd C

“…Abstract Biomaterials are increasingly being used to engineer the biochemical and biophysical properties of the extracellular stem cell microenvironment in…”
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Rotary Suspension Culture Enhances the Efficiency, Yield, and Homogeneity of Embryoid Body Differentiation by Carpenedo, Richard L., Sargent, Carolyn Y., McDevitt, Todd C.

“…Embryonic stem (ES) cells hold great promise as a robust cell source for cell‐based therapies and as a model of early embryonic development. Current…”
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Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation by Bratt-Leal, Andrés M., Carpenedo, Richard L., McDevitt, Todd C.

“…Embryonic stem cells (ESCs) are pluripotent cells capable of differentiating into all somatic and germ cell types. The intrinsic ability of pluripotent cells…”
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Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A by Chaturvedi, Chandra-Prakash, Somasundaram, Brinda, Singh, Kulwant, Carpenedo, Richard L, Stanford, William L, Dilworth, F. Jeffrey, Brand, Marjorie

“…Chromatin remodeling is essential for controlling the expression of genes during development. The histone-modifying enzyme G9a/KMT1C can act both as a…”
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Hydrodynamic modulation of embryonic stem cell differentiation by rotary orbital suspension culture by Sargent, Carolyn Y, Berguig, Geoffrey Y, Kinney, Melissa A, Hiatt, Luke A, Carpenedo, Richard L, Berson, R. Eric, McDevitt, Todd C

“…Embryonic stem cells (ESCs) can differentiate into all somatic cell types, but the development of effective strategies to direct ESC fate is dependent upon…”
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Homogeneous and organized differentiation within embryoid bodies induced by microsphere-mediated delivery of small molecules by Carpenedo, Richard L, Bratt-Leal, Andrés M, Marklein, Ross A, Seaman, Scott A, Bowen, Nathan J, McDonald, John F, McDevitt, Todd C

“…Abstract Cell specification and tissue formation during embryonic development are precisely controlled by the local concentration and temporal presentation of…”
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Microsphere size effects on embryoid body incorporation and embryonic stem cell differentiation by Carpenedo, Richard L., Seaman, Scott A., McDevitt, Todd C.

“…Differentiation of pluripotent embryonic stem cells (ESCs) in vitro via multicellular spheroids called embryoid bodies (EBs) is commonly performed to model…”
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Transcriptomically Guided Mesendoderm Induction of Human Pluripotent Stem Cells Using a Systematically Defined Culture Scheme by Carpenedo, Richard L., Kwon, Sarah Y., Tanner, R. Matthew, Yockell-Lelièvre, Julien, Choey, Chandarong, Doré, Carole, Ho, Mirabelle, Stewart, Duncan J., Perkins, Theodore J., Stanford, William L.

“…Human pluripotent stem cells (hPSCs) are an essential cell source in tissue engineering, studies of development, and disease modeling. Efficient, broadly…”
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Derivation and Expansion of PAX7-Positive Muscle Progenitors from Human and Mouse Embryonic Stem Cells by Shelton, Michael, Metz, Jeff, Liu, Jun, Carpenedo, Richard L., Demers, Simon-Pierre, Stanford, William L., Skerjanc, Ilona S.

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MKRN1: Uncovering function by an unbiased systems approach by Carpenedo, Richard L., Cassar, Paul A., Stanford, William L.

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Formula G1: Cell cycle in the driver's seat of stem cell fate determination by Julian, Lisa M., Carpenedo, Richard L., Rothberg, Janet L. Manias, Stanford, William L.

“…Cell cycle dynamics has emerged as a key regulator of stem cell fate decisions. In particular, differentiation decisions are associated with the G1 phase, and…”
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Human pluripotent stem cells by Carpenedo, Richard L., Julian, Lisa M., Stanford, William L.

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Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network by Cassar, Paul A, Carpenedo, Richard L, Samavarchi-Tehrani, Payman, Olsen, Jonathan B, Park, Chang Jun, Chang, Wing Y, Chen, Zhaoyi, Choey, Chandarong, Delaney, Sean, Guo, Huishan, Guo, Hongbo, Tanner, R Matthew, Perkins, Theodore J, Tenenbaum, Scott A, Emili, Andrew, Wrana, Jeffrey L, Gibbings, Derrick, Stanford, William L

“…In embryonic stem cells (ESCs), gene regulatory networks (GRNs) coordinate gene expression to maintain ESC identity; however, the complete repertoire of…”
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Magnetic manipulation and spatial patterning of multi-cellular stem cell aggregates by Bratt-Leal, Andrés M, Kepple, Kirsten L, Carpenedo, Richard L, Cooke, Marissa T, McDevitt, Todd C

“…The controlled assembly and organization of multi-cellular systems to mimic complex tissue structures is critical to the engineering of tissues for therapeutic…”
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Engineering the 3D microenvironment of embryonic stem cells undergoing differentiation by McDevitt, Todd C, Carpenedo, Richard L, Sargent, Carolyn Y, Berguig, Geoffrey Y, Marklein, Ross A, Seaman, Scott

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Integrative genomics positions MKRN 1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network by Cassar, Paul A, Carpenedo, Richard L, Samavarchi‐Tehrani, Payman, Olsen, Jonathan B, Park, Chang Jun, Chang, Wing Y, Chen, Zhaoyi, Choey, Chandarong, Delaney, Sean, Guo, Huishan, Guo, Hongbo, Tanner, R Matthew, Perkins, Theodore J, Tenenbaum, Scott A, Emili, Andrew, Wrana, Jeffrey L, Gibbings, Derrick, Stanford, William L

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Magnetic manipulation and spatial patterning of multi-cellular stem cell aggregatesElectronic supplementary information (ESI) available. See DOI: 10.1039/c1ib00064k by Bratt-Leal, Andrés M, Kepple, Kirsten L, Carpenedo, Richard L, Cooke, Marissa T, McDevitt, Todd C

“…The controlled assembly and organization of multi-cellular systems to mimic complex tissue structures is critical to the engineering of tissues for therapeutic…”
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Microsphere-mediated control of embryoid body microenvironments by Carpenedo, Richard L

“…Embryonic stem cells (ESCs) hold great promise for treatment of degenerative disorders such as Parkinson's and Alzheimer's disease, diabetes, and…”
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Microsphere-mediated control of embryoid body microenvironments by Carpenedo, Richard L

“…Embryonic stem cells (ESCs) hold great promise for treatment of degenerative disorders such as Parkinson's and Alzheimer's disease, diabetes, and…”
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