Search Results - "Carpaneto, Elisabetta M."
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Effects in live cells of a c- myc anti-gene PNA linked to a nuclear localization signal
Published in Nature biotechnology (01-03-2000)“…Peptide nucleic acids (PNA) are synthetic homologs of nucleic acids in which the phosphate-sugar polynucleotide backbone is replaced by a flexible polyamide…”
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Inhibition of the translocated c-myc in Burkitt's Lymphoma by a PNA complementary to the Eμ enhancer
Published in Cancer research (Chicago, Ill.) (01-10-2003)“…In Burkitt's Lymphoma there is an up-regulation of the c-myc oncogene caused by its translocation from chromosome 8 to chromosome 14, often close to the E mu…”
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Correlation between butyrate-induced histone hyperacetylation turn-over and c-myc expression
Published in The Journal of steroid biochemistry and molecular biology (01-08-2003)“…Transcriptionally active chromatin has an high level of histone acetylation, a post-transcriptional modification known to alter nucleosomal conformation…”
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Invasion of the CAG Triplet Repeats by a Complementary Peptide Nucleic Acid Inhibits Transcription of the Androgen Receptor and TATA-binding Protein Genes and Correlates with Refolding of an Active Nucleosome Containing a Unique AR Gene Sequence
Published in The Journal of biological chemistry (31-05-1996)“…The DNA sequence of the genes for the androgen receptor (AR) and TATA-binding protein (TBP), like many other genes encoding transcription factors, contains a…”
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5
Isolation of Active Genes Containing CAG Repeats by DNA Strand Invasion by a Peptide Nucleic Acid
Published in Proceedings of the National Academy of Sciences - PNAS (14-03-1995)“…An amplification of tandem CAG trinucleotide sequences in DNA due to errors in DNA replication is involved in at least four hereditary neurodegenerative…”
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Contrasting effects of PNA invasion of the chimeric DMMYC gene on transcription of its myc and PVT domains
Published in Oncology research (1997)“…A peptide nucleic acid (PNA) complementary to a unique DNA sequence in the second exon of the human myc proto-oncogene was tested for its effects on…”
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Recovery of transcriptionally active chromatin restriction fragments by binding to organomercurial-agarose magnetic beads. A rapid and sensitive method for monitoring changes in higher order chromatin structure during gene activation and repression
Published in The Journal of biological chemistry (05-11-1993)“…The unfolding of nucleosomes along transcriptionally active DNA sequences uncovers previously shielded cysteinyl-thiol groups of histone H3 molecules located…”
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Effects of N-methyl-N-nitrosourea on transcriptionally active and inactive nucleosomes: macromolecular damage and DNA repair
Published in Molecular carcinogenesis (1992)“…We previously reported a separation, on an organomercurial column, of transcriptionally inactive nucleosomes (class 1) from those containing active gene…”
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