Search Results - "Caron, Tyler"

Loss of Tight Junction Protein Claudin 18 Promotes Progressive Neoplasia Development in Mouse Stomach by Hagen, Susan J., Ang, Lay-Hong, Zheng, Yi, Karahan, Salih N., Wu, Jessica, Wang, Yaoyu E., Caron, Tyler J., Gad, Aniket P., Muthupalani, Sureshkumar, Fox, James G.

“…Loss of claudin 18 (CLDN18), a membrane-spanning tight junction protein, occurs during early stages of development of gastric cancer and associates with…”
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Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier by Caron, Tyler J, Scott, Kathleen E, Fox, James G, Hagen, Susan J

“…Long-term chronic infection with Helicobacter pylori(H. pylori) is a risk factor for gastric cancer development. In the multi-step process that leads to…”
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Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints by Minikel, Eric Vallabh, Zhao, Hien T, Le, Jason, O’Moore, Jill, Pitstick, Rose, Graffam, Samantha, Carlson, George A, Kavanaugh, Michael P, Kriz, Jasna, Kim, Jae Beom, Ma, Jiyan, Wille, Holger, Aiken, Judd, McKenzie, Deborah, Doh-ura, Katsumi, Beck, Matthew, O’Keefe, Rhonda, Stathopoulos, Jacquelyn, Caron, Tyler, Schreiber, Stuart L, Carroll, Jeffrey B, Kordasiewicz, Holly B, Cabin, Deborah E, Vallabh, Sonia M

“…Abstract Lowering of prion protein (PrP) expression in the brain is a genetically validated therapeutic hypothesis in prion disease. We recently showed that…”
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Cytotoxic Escherichia coli strains encoding colibactin isolated from immunocompromised mice with urosepsis and meningitis by Bakthavatchalu, Vasudevan, Wert, Katherine J, Feng, Yan, Mannion, Anthony, Ge, Zhongming, Garcia, Alexis, Scott, Kathleen E, Caron, Tyler J, Madden, Carolyn M, Jacobsen, Johanne T, Victora, Gabriel, Jaenisch, Rudolf, Fox, James G

“…Immune-compromised mouse models allow for testing the preclinical efficacy of human cell transplantations and gene therapy strategies before moving forward to…”
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Altered Subcellular Localization of c-Myc Protein Identifies Aggressive B-cell Lymphomas Harboring a c-MYC Translocation by RUZINOVA, Marianna B, CARON, Tyler, RODIG, Scott J

“…Nearly 100% of Burkitt lymphomas (BLs) and 5% to 8% of diffuse large B-cell lymphomas (DLBCLs) harbor a balanced translocation involving c-MYC. Although…”
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CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells by O'Brien, Karen B, Alberich-Jordà, Meritxell, Yadav, Neelu, Kocher, Olivier, Diruscio, Annalisa, Ebralidze, Alexander, Levantini, Elena, Sng, Natasha J L, Bhasin, Manoj, Caron, Tyler, Kim, Daehoon, Steidl, Ulrich, Huang, Gang, Halmos, Balázs, Rodig, Scott J, Bedford, Mark T, Tenen, Daniel G, Kobayashi, Susumu

“…Coactivator-associated arginine methyltransferase I (CARM1; PRMT4) regulates gene expression by multiple mechanisms including methylation of histones and…”
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Cutaneous Dermatophilosis in a Meadow Jumping Mouse (Zapus hudsonius) by Caron, Tyler J, Artim, Stephen C, Israelsen, William J, Holcombe, Hilda R, Fox, James G, Bakthavatchalu, Vasudevan

“…A laboratory-housed, wild-caught, subadult, male meadow jumping mouse (Zapus hudsonius) presented with extensive scaling of the face, limbs, and tail and…”
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Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial Cells by Caron, Tyler J., Scott, Kathleen E., Sinha, Nishita, Muthupalani, Sureshkumar, Baqai, Mahnoor, Ang, Lay-Hong, Li, Yue, Turner, Jerrold R., Fox, James G., Hagen, Susan J.

“…Tight junctions form a barrier to the paracellular passage of luminal antigens. Although most tight junction proteins reside within the apical tight junction…”
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Serosurvey for Brucella spp. and Coxiella burnetii in animals on Caribbean islands by Johnson, Jason W., Lucas, Helene, King, Sharon, Caron, Tyler, Wang, Chengming, Kelly, Patrick J.

“…To determine the prevalence of antibodies to Brucella melitensis, Brucella abortus and Coxiella burnetii in animals on Caribbean islands we obtained sera from…”
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Evaluation of Best Practices for the Euthanasia of Zebra Finches (Taeniopygia guttata) by Scott, Kathleen E, Bracchi, Lauren A, Lieberman, Mia T, Hill, Nichola J, Caron, Tyler J, Patterson, Mary M

“…Although zebra finches (Taeniopygia guttata) have been used in biomedical research for many years, no published reports are available about euthanizing these…”
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Epstein–Barr virus infection is not a characteristic feature of multiple sclerosis brain by Willis, Simon N., Stadelmann, Christine, Rodig, Scott J., Caron, Tyler, Gattenloehner, Stefan, Mallozzi, Scott S., Roughan, Jill E., Almendinger, Stefany E., Blewett, Megan M., Brück, Wolfgang, Hafler, David A., O’Connor, Kevin C.

“…Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system (CNS) that is thought to be caused by a combination of genetic and…”
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Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis by LOVATO, Laura, WILLIS, Simon N, RODIG, Scott J, CARON, Tyler, ALMENDINGER, Stefany E, HOWELL, Owain W, REYNOLDS, Richard, O'CONNOR, Kevin C, HAFLER, David A

“…In the central nervous system of patients with multiple sclerosis, B cell aggregates populate the meninges, raising the central question as to whether these…”
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Loss of Tight Junction Protein Claudin-18 Promotes Rapid Cancer Development in Mouse Stomach by Hagen, Susan J., Ang, Lay-Hong, Zheng, Yi, Karahan, Salih N., Wu, Jessica, Wang, Yaoyu E., Caron, Tyler, Gad, Aniket, Muthupalani, Sureshkumar, Fox, James G.

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CLDN18 Loss Affects Transcellular Cl‐Permeability Rather than Dysregulating Tight Junctions by Caron, Tyler J, Sinha, Nishita, Scott, Kathleen E, Ang, Lay‐Hong, Fox, James G, Hagen, Susan J

“…Abstract only Loss of tight junction integrity is an important risk factor for H. pylori ‐mediated gastric cancer (GC) development. The loss of claudin…”
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Antisense oligonucleotides extend survival of prion-infected mice by Raymond, Gregory J, Zhao, Hien Tran, Race, Brent, Raymond, Lynne D, Williams, Katie, Swayze, Eric E, Graffam, Samantha, Le, Jason, Caron, Tyler, Stathopoulos, Jacquelyn, O'Keefe, Rhonda, Lubke, Lori L, Reidenbach, Andrew G, Kraus, Allison, Schreiber, Stuart L, Mazur, Curt, Cabin, Deborah E, Carroll, Jeffrey B, Minikel, Eric Vallabh, Kordasiewicz, Holly, Caughey, Byron, Vallabh, Sonia M

“…Prion disease is a fatal, incurable neurodegenerative disease of humans and other mammals caused by conversion of cellular prion protein (PrP; PrPC) into a…”
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The Microenvironment of Germ Cell Tumors Harbors a Prominent Antigen-Driven Humoral Response by Willis, Simon N, Mallozzi, Scott S, Rodig, Scott J, Cronk, Katherine M, McArdel, Shannon L, Caron, Tyler, Pinkus, Geraldine S, Lovato, Laura, Shampain, Kimberly L, Anderson, David E, Anderson, Richard C. E, Bruce, Jeffrey N, O'Connor, Kevin C

“…Germ cell tumors are a heterogeneous group of neoplasms derived from residual primordial tissue. These tumors are commonly found in the brain, testes, or…”
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Epithelial adhesion molecules can inhibit HIV-1–specific CD8+ T-cell functions by Streeck, Hendrik, Kwon, Douglas S., Pyo, Augustine, Flanders, Michael, Chevalier, Mathieu F., Law, Kenneth, Jülg, Boris, Trocha, Kasper, Jolin, Jonathan S., Anahtar, Melis N., Lian, Jeff, Toth, Ildiko, Brumme, Zabrina, Chang, J. Judy, Caron, Tyler, Rodig, Scott J., Milner, Danny A., Piechoka-Trocha, Alicja, Kaufmann, Daniel E., Walker, Bruce D., Altfeld, Marcus

“…Under persistent antigenic stimulation, virus-specific CD8+ T cells become increasingly dysfunctional and up-regulate several inhibitory molecules such as…”
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CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells by O'Brien, Karen B., Alberich-Jordà, Meritxell, Yadav, Neelu, Kocher, Olivier, DiRuscio, Annalisa, Ebralidze, Alexander, Levantini, Elena, Sng, Natasha J. L., Bhasin, Manoj, Caron, Tyler, Kim, Daehoon, Steidl, Ulrich, Huang, Gang, Halmos, Balázs, Rodig, Scott J., Bedford, Mark T., Tenen, Daniel G., Kobayashi, Susumu

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Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial CellsSummary by Tyler J. Caron, Kathleen E. Scott, Nishita Sinha, Sureshkumar Muthupalani, Mahnoor Baqai, Lay-Hong Ang, Yue Li, Jerrold R. Turner, James G. Fox, Susan J. Hagen

“…Background & Aims: Tight junctions form a barrier to the paracellular passage of luminal antigens. Although most tight junction proteins reside within the…”
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