Search Results - "Carolina Panis"
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CTLA-4 Expression and Its Clinical Significance in Breast Cancer
Published in Archivum Immunologiae et Therapiae Experimentalis (01-12-2021)“…Breast cancer is the leading cause of women’s death among all cancers. The main reason associated with this is the development of metastasis and…”
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Widespread pesticide contamination of drinking water and impact on cancer risk in Brazil
Published in Environment international (01-07-2022)“…[Display omitted] Pesticides, which are associated with endocrine dysfunction, immunological dysregulation, and cancer, are widespread sources of drinking…”
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Editorial: Global excellence in oncology: Latin America 2022
Published in Frontiers in oncology (12-07-2022)Get full text
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Metformin prevention of doxorubicin resistance in MCF-7 and MDA-MB-231 involves oxidative stress generation and modulation of cell adaptation genes
Published in Scientific reports (10-04-2019)“…Metformin was shown to sensitize multidrug resistant breast cancer cells; however, the mechanisms involved in this capacity need to be clarified. We…”
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NRIP1 is activated by C-JUN/C-FOS and activates the expression of PGR, ESR1 and CCND1 in luminal A breast cancer
Published in Scientific reports (27-10-2021)“…Using chip array assays, we identified differentially expressed genes via a comparison between luminal A breast cancer subtype and normal mammary ductal cells…”
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Cytokines as Mediators of Pain-Related Process in Breast Cancer
Published in Mediators of Inflammation (01-01-2015)“…Pain is a clinical sign of inflammation found in a wide variety of chronic pathologies, including cancer. The occurrence of pain in patients carrying breast…”
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Quercetin promotes antipromastigote effect by increasing the ROS production and anti-amastigote by upregulating Nrf2/HO-1 expression, affecting iron availability
Published in Biomedicine & pharmacotherapy (01-05-2019)“…[Display omitted] •Quercetin inhibits the proliferation of L. braziliensis promastigote forms.•Quercetin reduces the percentage of infection and number of…”
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Polymorphisms in GSTT1 and GSTM1 genes as possible risk factors for susceptibility to breast cancer development and their influence in chemotherapy response: a systematic review
Published in Molecular biology reports (01-07-2020)“…Breast cancer (BC) is a heterogeneous and multifactorial disease. The system formed by glutathione- S -transferases (GSTs) acts to protect the organism against…”
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Oxidative stress, redox signaling and cancer chemoresistance: putting together the pieces of the puzzle
Published in Current medicinal chemistry (01-01-2014)“…Chemotherapy continues to be the main treatment option for cancer. Although systemic chemotherapy can efficiently eradicate cancer cells, a significant…”
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Putative circulating markers of the early and advanced stages of breast cancer identified by high-resolution label-free proteomics
Published in Cancer letters (01-03-2013)“…Highlights ► Breast cancer proteomics. ► Plasma proteomics. ► MuDPIT proteomic strategy…”
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Pesticides, Drinking Water and Cancer Risk: A Portrait of Paraná Southwest, Brazil
Published in Pollutants (26-06-2024)“…A 2018 report from the Water Quality for Human Consumption Vigilance Information System (SISÁGUA, Brazil) showed the presence of 27 pesticides in Brazilian…”
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Lessons from transmissible cancers for immunotherapy and transplant
Published in Immunological medicine (03-07-2022)“…The emergence of horizontal transmission of cancer between vertebrates is an issue that interests scientists and medical society. Transmission requires: (i) a…”
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Decreased endothelial nitric oxide, systemic oxidative stress, and increased sympathetic modulation contribute to hypertension in obese rats
Published in American journal of physiology. Heart and circulatory physiology (15-05-2014)“…We investigated the involvement of nitric oxide (NO) and reactive oxygen species (ROS) on autonomic cardiovascular parameters, vascular reactivity, and…”
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Occupational exposure to pesticides dysregulates systemic Th1/Th2/Th17 cytokines and correlates with poor clinical outcomes in breast cancer patients
Published in Frontiers in immunology (24-10-2023)“…Pesticides are compounds known to cause immunetoxicity in exposed individuals, which have a potential to substantially modify the prognosis of pathologies…”
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miRNome Profiling Reveals Shared Features in Breast Cancer Subtypes and Highlights miRNAs That Potentially Regulate MYB and EZH2 Expression
Published in Frontiers in oncology (27-09-2021)“…Breast cancer (BC) has been extensively studied, as it is one of the more commonly diagnosed cancer types worldwide. The study of miRNAs has increased what is…”
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Effects of GSTT1 and GSTM1 polymorphisms in glutathione levels and breast cancer development in Brazilian patients
Published in Molecular biology reports (2021)“…Polymorphisms in the glutathione transferase enzymes (GSTs) genes have been associated with susceptibility to develop breast cancer (BC), but few are known…”
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Somatic DNA Damage Response and Homologous Repair Gene Alterations and Its Association With Tumor Variant Burden in Breast Cancer Patients With Occupational Exposure to Pesticides
Published in Frontiers in oncology (08-07-2022)“…Homologous recombination is a crucial pathway that is specialized in repairing double-strand breaks; thus, alterations in genes of this pathway may lead to…”
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Naringenin and Hesperidin as Promising Alternatives for Prevention and Co-Adjuvant Therapy for Breast Cancer
Published in Antioxidants (27-02-2023)“…Citrus (genus L.) fruits are essential sources of bioactive compounds with antioxidant properties, such as flavonoids. These polyphenolic compounds are divided…”
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Evidence on Human Exposure to Pesticides and the Occurrence of Health Hazards in the Brazilian Population: A Systematic Review
Published in Frontiers in public health (07-01-2022)“…Brazil is among the biggest pesticide consumers in the world, with its population severely exposed to tons of such substances, both because of environmental…”
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