Search Results - "Carolina Díaz Arenas"
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Genetic background affects epistatic interactions between two beneficial mutations
Published in Biology letters (2005) (23-02-2013)“…The phenotypic effect of mutations can depend on their genetic background, a phenomenon known as epistasis. Many experimental studies have found that epistasis…”
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2
Partitioning the fitness components of RNA populations evolving in vitro
Published in PloS one (31-12-2013)“…All individuals in an evolving population compete for resources, and their performance is measured by a fitness metric. The performance of the individuals is…”
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3
Mechanisms and selection of evolvability: experimental evidence
Published in FEMS microbiology reviews (01-07-2013)“…Abstract The vast number of species we see around us today, all stemming from a common ancestor, clearly demonstrates the capacity of organisms to adapt to new…”
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Quasispecies-like behavior observed in catalytic RNA populations evolving in a test tube
Published in BMC evolutionary biology (23-03-2010)“…During the RNA World, molecular populations were probably very small and highly susceptible to the force of strong random drift. In conjunction with Muller's…”
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Accumulation of Deleterious Mutations in Small Abiotic Populations of RNA
Published in Genetics (Austin) (01-01-2007)“…The accumulation of slightly deleterious mutations in populations leads to the buildup of a genetic load and can cause the extinction of populations of small…”
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Complexity through Recombination: From Chemistry to Biology
Published in Entropy (Basel, Switzerland) (01-01-2011)“…Recombination is a common event in nature, with examples in physics, chemistry, and biology. This process is characterized by the spontaneous reorganization of…”
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Benefit of transferred mutations is better predicted by the fitness of recipients than by their ecological or genetic relatedness
Published in Proceedings of the National Academy of Sciences - PNAS (03-05-2016)“…The effect of a mutation depends on its interaction with the genetic background in which it is assessed. Studies in experimental systems have demonstrated that…”
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Correction: Partitioning the Fitness Components of RNA Populations Evolving In Vitro
Published in PloS one (01-01-2014)“…Sub-figure 1A is incorrectly omitted from Figure 1. Please view sub-figure 1A here: thumbnail Download: * PPT PowerPoint slide * PNG larger image * TIFF…”
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Darwin’s concepts in a test tube: Parallels between organismal and in vitro evolution
Published in The international journal of biochemistry & cell biology (01-02-2009)“…The evolutionary process as imagined by Darwin 150 years ago is evident not only in nature but also in the manner in which naked nucleic acids and proteins…”
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Gel purification of radiolabeled nucleic acids via phosphorimaging: Dip-N-Dot
Published in Analytical biochemistry (15-05-2009)“…RNA and DNA oligonucleotides radiolabeled with 32P or 33P often require gel electrophoresis to remove undesired side and/or degradation products. Common ways…”
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Ribozyme Mutagenic Evolution: Mechanisms of Survival
Published in Origins of life and evolution of biospheres (01-12-2021)“…Primeval populations replicating at high error rates required a mechanism to overcome the accumulation of mutations and information deterioration. Known…”
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Diminishing-returns epistasis decreases adaptability along an evolutionary trajectory
Published in Nature ecology & evolution (01-03-2017)“…Populations evolving in constant environments exhibit declining adaptability. Understanding the basis of this pattern could reveal underlying processes…”
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Correction: Partitioning the Fitness Components of RNA Populations Evolving
Published in PloS one (01-01-2014)Get full text
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14
The continuous evolution in vitro technique
Published in Current protocols in nucleic acid chemistry (01-03-2010)“…In vitro experimentation techniques were developed in response to the necessity of exploring new molecular structures and functions and to better understand…”
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Partitioning the Fitness Components of RNA Populations Evolving In Vitro: e84454
Published in PloS one (01-12-2013)“…All individuals in an evolving population compete for resources, and their performance is measured by a fitness metric. The performance of the individuals is…”
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16
Evolutionary dynamics in molecular populations of ligase ribozymes
Published 01-01-2010“…The emergence of life depended on the ability of the first biopolymer populations to thrive and approach larger population sizes and longer sequences that…”
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Dissertation -
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Evolutionary dynamics in molecular populations of ligase ribozymes
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Dissertation -
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Identificación y análisis de secuencias consenso de RNAs de transferencia aminoácido específicos, según la procedencia biológica
Published in Acta biológica colombiana (01-01-2003)“…Desde el descubrimiento del código genético se han llevado a cabo varios estudios sobre el tRNA, debido a su gran importancia en la síntesis de proteínas. En…”
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Journal Article