Search Results - "Carobrez, A P"

Ethological and temporal analyses of anxiety-like behavior: The elevated plus-maze model 20 years on by Carobrez, A.P., Bertoglio, L.J.

“…As well as being considered a reliable measurement instrument of animal anxiety-like behavior, the elevated plus-maze (EPM) is also used as a post-hoc test to…”
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Activity in prelimbic cortex is required for adjusting the anxiety response level during the elevated plus-maze retest by Stern, C.A.J, Do Monte, F.H.M, Gazarini, L, Carobrez, A.P, Bertoglio, L.J

“…Abstract The prelimbic (PL) subregion of medial prefrontal cortex has been implicated in anxiety regulation. It is unknown, however, whether PL cortex also…”
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Organization of single components of defensive behaviors within distinct columns of periaqueductal gray matter of the rat: role of N-METHYL- d-aspartic acid glutamate receptors by Bittencourt, A.S., Carobrez, A.P., Zamprogno, L.P., Tufik, S., Schenberg, L.C.

“…The periaqueductal gray matter (PAG) is functionally organized in longitudinal columns arranged along the aqueduct. Stimulation of lateral and dorsal columns…”
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Aversive learning as a mechanism for lack of repeated anxiolytic-like effect in the elevated plus-maze by Stern, C.A.J., Carobrez, A.P., Bertoglio, L.J.

“…Rodents re-exposed to the elevated plus-maze no longer respond to anxiolytic-like drugs, such as benzodiazepines. This phenomenon is thought to be due to…”
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Prior maze experience required to alter midazolam effects in rats submitted to the elevated plus-maze by Bertoglio, L.J., Carobrez, A.P.

“…In rodents, prior maze experience increases open arm avoidance (OAA) and compromises the anxiolytic effects of benzodiazepines in a subsequent exposure to the…”
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Anxiolytic effects of ethanol and phenobarbital are abolished in test-experienced rats submitted to the elevated plus maze by Bertoglio, L.J, Carobrez, A.P

“…Prior test experience compromises the anxiolytic efficacy of benzodiazepines (BZs) either in rats or mice, a phenomenon not exclusive to the elevated plus-maze…”
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Scopolamine given pre-Trial 1 prevents the one-trial tolerance phenomenon in the elevated plus-maze Trial 2 by Bertoglio, L. J, Carobrez, A. P

“…A learned avoidance response has been one of the hypotheses proposed to explain the ‘one-trial tolerance’ (OTT) phenomenon, which represents a drugʼs loss of…”
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Previous maze experience required to increase open arms avoidance in rats submitted to the elevated plus-maze model of anxiety by Bertoglio, Leandro J, Carobrez, Antonio P

“…Studies have shown an increased open arm avoidance in rats re-exposed to the elevated plus-maze (EPM), which suggests a qualitative shift in emotional states…”
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Sex differences in fear memory and extinction of mice with forebrain-specific disruption of the mineralocorticoid receptor by ter Horst, J. P., Carobrez, A. P., van der Mark, M. H., de Kloet, E. R., Oitzl, M. S.

“…Previous studies showed that the mineralocorticoid receptor (MR) is needed for behavioral flexibility in a fear conditioning paradigm. Female mice with…”
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Lack of midazolam-induced anxiolysis in the plus-maze Trial 2 is dependent on the length of Trial 1 by Dal-Cól, M.L.C, Pereira, L.Orlandi, Rosa, V.P, Calixto, A.V, Carobrez, A.P, Faria, M.S

“…The influence of the first exposure length upon the effect of midazolam (MDZ) administration prior to the second exposure in the elevated plus-maze (EPM) was…”
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Elevated T-maze as an animal model of memory: effects of scopolamine by De-Mello, N, Carobrez, A.P

“…The elevated T-maze (ETM) is a putative model for the assessment of anxiety and memory in rodents. This study was designed to further evaluate the utility of…”
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Effects of glycine or (±)-3-amino-1-hydroxy-2-pyrrolidone microinjections along the rostrocaudal axis of the dorsal periaqueductal gray matter on rats' performance in the elevated plus-maze task by TEIXEIRA, K. V, CAROBREZ, A. P

“…The effects of glycine (GLY) or (+/-)-3-amino-1-hydroxy-2-pyrrolidone (HA966), a GLY receptor antagonist, microinjections into sites along the rostrocaudal…”
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Influence of gender and age on performance of rats in the elevated plus maze apparatus by Imhof, J T, Coelho, Z M, Schmitt, M L, Morato, G S, Carobrez, A P

“…We have compared the performance of male and female Wistar rats at different ages (45, 60, 90, 120 and 150 days) in the elevated plus-maze test, a reliable…”
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Anxiolytic effect in the elevated plus-maze of the NMDA receptor antagonist AP7 microinjected into the dorsal periaqueductal grey by GUIMARAES, F. S, CAROBREZ, A. P, DE AGUIAR, J. C, GRAEFF, F. G

“…In order to localise the often reported anxiolytic action of N-methyl-D-aspartate (NMDA) receptor antagonists, 2-amino-7-phosphonoheptanoic acid (AP7) was…”
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Activation of dorsal periaqueductal gray by glycine produces long lasting hyponociception in rats without overt defensive behaviors by Martins, M.A., Carobrez, A.P., Tonussi, C.R.

“…Electrical or glutamate stimulation of the dorsal periaqueductal gray matter (DPAG) of rats induces overt defensive behavior, such as freezing or flight, and…”
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Anxiolytic effect of glycine antagonists microinjected into the dorsal periaqueductal grey by MATHEUS, M. G, NOGUEIRA, R. L, CAROBREZ, A. P, GRAEFF, F. G, GUIMARAES, F. S

“…To investigate if blockade of the modulatory glycine site of NMDA receptors in the dorsal periaqueductal grey (DPAG) would produce anxiolytic effects, groups…”
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Anxiogenic-like effect of glycine and d-serine microinjected into dorsal periaqueductal gray matter of rats by Schmitt, M.L., Coelho, W., Lopes-de-Souza, A.S., Guimarães, F.S., Carobrez, A.P.

“…The glutamatergic system of the dorsal periaqueductal gray matter (DPAG) has been implicated in anxiety. This study shows that microinjections of glycine (GLY)…”
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Long-lasting inhibitory avoidance acquisition in rats submitted to the elevated T-maze model of anxiety by Sanson, Luciana T, Carobrez, Antonio P

“…The present study was outlined in order to provide additional behavioral validation to the elevated T-maze as a model of anxiety and memory. In this model,…”
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The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis by Andreatini, R, Blanchard, C, Blanchard, R, Brandão, M L, Carobrez, A P, Griebel, G, Guimarães, F S, Handley, S L, Jenck, F, Leite, J R, Rodgers, J, Schenberg, L C, Da Cunha, C, Graeff, F G

“…This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from…”
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Behavioral profile of rats submitted to session 1-session 2 in the elevated plus-maze during diurnal/nocturnal phases and under different illumination conditions by Bertoglio, Leandro J, Carobrez, Antonio P

“…The elevated plus-maze (EPM) model usually employs nocturnal species (e.g. rats and mice) and the tests are almost exclusively performed during the diurnal…”
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