Search Results - "Caro, Marta"
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Protective role of cortistatin in pulmonary inflammation and fibrosis
Published in British journal of pharmacology (01-11-2021)“…Background and Purpose Acute lung injury (ALI), acute respiratory distress syndrome (ARDS) and pulmonary fibrosis remain major causes of morbidity, mortality…”
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Local Model-Agnostic Explanations for Black-box Recommender Systems Using Interaction Graphs and Link Prediction Techniques
Published in International journal of interactive multimedia and artificial intelligence (01-06-2023)“…Explanations in recommender systems are a requirement to improve users' trust and experience. Traditionally, explanations in recommender systems are derived…”
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The atypical RhoGTPase RhoE/Rnd3 is a key molecule to acquire a neuroprotective phenotype in microglia
Published in Journal of neuroinflammation (15-12-2018)“…Over-activated microglia play a central role during neuroinflammation, leading to neuronal cell death and neurodegeneration. Reversion of over-activated to…”
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Cortistatin deficiency reveals a dysfunctional brain endothelium with impaired gene pathways, exacerbated immune activation, and disrupted barrier integrity
Published in Journal of neuroinflammation (04-10-2023)“…Background Brain activity governing cognition and behaviour depends on the fine-tuned microenvironment provided by a tightly controlled blood-brain barrier…”
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Cortistatin as a Novel Multimodal Therapy for the Treatment of Parkinson's Disease
Published in International journal of molecular sciences (01-01-2024)“…Parkinson's disease (PD) is a complex disorder characterized by the impairment of the dopaminergic nigrostriatal system. PD has duplicated its global burden in…”
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Mesenchymal stem cells induce the ramification of microglia via the small RhoGTPases Cdc42 and Rac1
Published in Glia (01-12-2014)“…Activated microglia play a central role in the course of neurodegenerative diseases as they secrete cytotoxic substances which lead to neuronal cell death…”
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Correction to: The atypical RhoGTPase RhoE/Rnd3 is a key molecule to acquire a neuroprotective phenotype in microglia
Published in Journal of neuroinflammation (12-02-2019)“…In the version of this article that was originally published [1]; some information in the "Author's contributions" section was omitted…”
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Historia y ambiente: el agua como nexo
Published in Relaciones internacionales (Madrid) (01-10-2020)“…A review essay covering books by 1) J. Linton, What is Water? The History of a Modern Abstraction (2010) and 2) A. Faccendini, La nueva humanización del agua…”
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Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants
Published in PloS one (26-10-2010)“…Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized pathologically by the presence in the brain of intracellular protein…”
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The Neuropeptide Cortistatin Alleviates Neuropathic Pain in Experimental Models of Peripheral Nerve Injury
Published in Pharmaceutics (24-06-2021)“…Neuropathic pain is one of the most severe forms of chronic pain caused by the direct injury of the somatosensory system. The current drugs for treating…”
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THE NEUROPEPTIDE CORTISTATIN REGULATES THE PROGRAMMING OF BRAIN ENDOTHELIAL CELLS UNDER PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS
Published in IBRO neuroscience reports (01-10-2023)Get full text
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A practical exploration of the convergence of Case-Based Reasoning and Explainable Artificial Intelligence
Published in Expert systems with applications (01-12-2024)“…As Artificial Intelligence (AI) systems become increasingly complex, ensuring their decisions are transparent and understandable to users has become paramount…”
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A graph-based approach for minimising the knowledge requirement of explainable recommender systems
Published in Knowledge and information systems (01-10-2023)“…Traditionally, recommender systems use collaborative filtering or content-based approaches based on ratings and item descriptions. However, this information is…”
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Case-based selection of explanation methods for neural network image classifiers
Published in Knowledge-based systems (15-03-2024)“…Deep learning is especially remarkable in terms of image classification. However, the outcomes of models are not explainable to users due to their complex…”
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iSee: A case-based reasoning platform for the design of explanation experiences
Published in Knowledge-based systems (25-10-2024)“…Explainable Artificial Intelligence (XAI) is an emerging field within Artificial Intelligence (AI) that has provided many methods that enable humans to…”
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Adipose-derived mesenchymal stromal cells induce immunomodulatory macrophages which protect from experimental colitis and sepsis
Published in Gut (01-08-2013)“…To investigate the effect of adipose-derived mesenchymal stromal cells (ASCs) on the activation state of macrophages (MΦ) in vitro, and the potential…”
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Human amnion favours tissue repair by inducing the M1‐to‐M2 switch and enhancing M2 macrophage features
Published in Journal of tissue engineering and regenerative medicine (01-10-2017)“…Human amniotic mesenchymal cells (hAMTCs) possess interesting immunomodulatory properties, making them attractive candidates for regenerative medicine…”
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Cortistatin regulates fibrosis and myofibroblast activation in experimental hepatotoxic‐ and cholestatic‐induced liver injury
Published in British journal of pharmacology (01-05-2022)“…Background and Purpose Liver fibrosis induced by chronic hepatic injury remains a major cause of morbidity and mortality worldwide. Identification of…”
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Alkylated resveratrol prodrugs and metabolites as potential therapeutics for neurodegenerative diseases
Published in European journal of medicinal chemistry (25-02-2018)“…Resveratrol is a naturally occurring stilbene which has shown promising results as treatment for several neurodegenerative diseases. However, its application…”
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