Search Results - "Carnwath, J W"

Genome-wide expression profiling reveals distinct clusters of transcriptional regulation during bovine preimplantation development in vivo by Kues, W.A, Sudheer, S, Herrmann, D, Carnwath, J.W, Havlicek, V, Besenfelder, U, Lehrach, H, Adjaye, J, Niemann, H

“…Bovine embryos can be generated by in vitro fertilization or somatic nuclear transfer; however, these differ from their in vivo counterparts in many aspects…”
Get full text

Expression Pattern of Oct-4 in Preimplantation Embryos of Different Species by Kirchhof, N, Carnwath, J. W, Lemme, E, Anastassiadis, K, Schöler, H, Niemann, H

“…POU transcription factors are involved in transcriptional regulation during early embryonic development and cell differentiation. Oct-4, a member of this…”
Get full text

Alterations in the relative abundance of gene transcripts in preimplantation bovine embryos cultured in medium supplemented with either serum or PVA by Wrenzycki, C, Herrmann, D, Carnwath, J.W, Niemann, H

“…In preimplantation bovine embryos, the relative abundance of various developmentally important gene transcripts was determined by a semi‐quantitative RT‐PCR…”
Get full text

Cell cycle synchronization of porcine fetal fibroblasts: effects of serum deprivation and reversible cell cycle inhibitors by Kues, W.A, Anger, M, Carnwath, J.W, Paul, D, Motlik, J, Niemann, H

“…The success of somatic nuclear transfer critically depends on the cell cycle stage of the donor nucleus and the recipient cytoplast. In this study we tested…”
Get full text

Changes in the relative abundance of mRNA transcripts for insulin-like growth factor (IGF-I and IGF-II) ligands and their receptors (IGF-IR/IGF-IIR) in preimplantation bovine embryos derived from different in vitro systems by Yaseen, MA, Wrenzycki, C, Herrmann, D, Carnwath, JW, Niemann, H

“…The aim of this study was to determine the relative abundance of mRNAs for the insulin-like growth factor I (IGF-I) and IGF-II ligands, and for the IGF…”
Get full text

Expression of the gap junction gene connexin43 (Cx43) in preimplantation bovine embryos derived in vitro or in vivo by Wrenzycki, C, Herrmann, D, Carnwath, J W, Niemann, H

“…In this study we have examined the presence of mRNA encoding connexin 43 (Cx43) in bovine embryos derived in vivo and in vitro . Cumulus–oocyte complexes,…”
Get full text

The transgenic rabbit as model for human diseases and as a source of biologically active recombinant proteins by BÖSZE, Zs, HIRIPI, L, CARNWATH, J. W, NIEMANN, H

“…Until recently, transgenic rabbits were produced exclusively by pronuclear microinjection which results in additive random insertional transgenesis; however,…”
Get full text

Expression of RNA from developmentally important genes in preimplantation bovine embryos produced in TCM supplemented with BSA by Wrenzycki, C, Herrmann, D, Carnwath, J W, Niemann, H

“…This study investigated the effects of a semi-defined culture system on the temporal pattern of expression of RNA from genes involved in compaction and…”
Get full text

Transgenic farm animals: present and future by Niemann, H, Kues, W, Carnwath, J W

“…Until recently, pronuclear microinjection of deoxyribonucleic acid (DNA) was the standard method for producing transgenic animals. This technique is now being…”
Get full text

Differential regulation of galectin expression/reactivity during wound healing in porcine skin and in cultures of epidermal cells with functional impact on migration by Klíma, J, Lacina, L, Dvořánková, B, Herrmann, D, Carnwath, J W, Niemann, H, Kaltner, H, André, S, Motlík, J, Gabius, H-J, Smetana, Jr, K

“…The glycophenotyping of mammalian cells with plant lectins maps aspects of the glycomic profile and disease-associated alterations. A salient step toward…”
Get full text

Developmental competence and mRNA expression of preimplantation in vitro–produced embryos from prepubertal and postpubertal cattle and their relationship with apoptosis after intraovarian administration of IGF-1 by Zaraza, J., Oropeza, A., Velazquez, M.A., Korsawe, K., Herrmann, D., Carnwath, J.W., Niemann, H.

“…Recombinant human Insulin-like growth factor-I (hIGF-1) was administered to one ovary of prepubertal and postpubertal cattle to determine its effects on (1)…”
Get full text

Expression of active human blood clotting factor VIII in mammary gland of transgenic rabbits by Hiripi, L, Makovics, F, Halter, R, Baranyi, M, Paul, D, Carnwath, J W, Bösze, Zs, Niemann, H

“…Human clotting factor VIII is probably the largest protein to be expressed to date in the mammary gland of a transgenic animal, and it requires extensive…”
Get more information

Expression of human blood clotting factor VIII in the mammary gland of transgenic sheep by Niemann, H, Halter, R, Carnwath, J.W, Herrmann, D, Lemme, E, Paul, D

“…By targeting the expression of sequences encoding non-milk proteins to the mammary gland of transgenic farm animals, the organ could serve as a 'bioreactor'…”
Get full text

Application of DNA array technology to mammalian embryos by Niemann, H., Carnwath, J.W., Kues, W.

“…Early embryogenesis depends on a tightly choreographed succession of gene expression patterns which define normal development. Fertilization and the first…”
Get full text

Muscular dystrophy in the mdx mouse: histopathology of the soleus and extensor digitorum longus muscles by Carnwath, J W, Shotton, D M

“…We have used light microscopic histomorphometry to quantify the developmental histopathological changes induced by muscular dystrophy in the soleus and…”
Get more information

Analysis of two Chinese yak (Bos grunniens) populations using bovine microsatellite primers by Minqiang, Wang, Weigend, S., Barre-Dirie, A., Carnwath, J. W., Zhonglin, L., Niemann, H.

“…Summary Two Chinese domestic yak populations representing the Plateau type and the Huanhu Alpine type were analysed with 12 bovine microsatellite primers. All…”
Get full text

Isolation of Murine and Porcine Fetal Stem Cells from Somatic Tissue by KUES, Wilfried A, PETERSEN, Björn, MYSEGADES, Wiebke, CARNWATH, Joseph W, NIEMANN, Heiner

“…Adult stem cells have been previously isolated from a variety of somatic tissues, including bone marrow and the central nervous system; however, contribution…”
Get full text

New transgenic pigs for xenotransplantation, part 1 by Niemann, H., Petersen, B., Lucas-Hahn, A., Lemme, E., Oropeza, M., Herrmann, D., Kues, W., Barg-Kues, B., Carnwath, J. W.

“…The hyperacute rejection response (HAR) after porcine‐to‐human xenotransplantation can now be reliably overcome. The next immunological hurdle is the acute…”
Get full text

Automated recording of RNA differential display patterns from pig granulosa cells by Motlik, J, Carnwath, J W, Herrmann, D, Terletski, V, Anger, M, Niemann, H

“…We have developed a protocol for fast, nonradioactive, mRNA differential display reverse transcription PCR (DDRT-PCR) based on a commercial automated sequencer…”
Get full text

High incidence of single nucleotide polymorphisms in the prion protein gene of native Brazilian Caracu cattle by Kues, W.A, Ollhoff, R.D, Carnwath, J.W, Souza, F.P. de, Madeira, H.M.F, Niemann, H

“…Different alleles of the human and ovine prion protein gene correlate with a varying susceptibility to transmissible spongiform encephalopathies. However, the…”
Get full text