Search Results - "Carney, John P."
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Multimodal preoperative imaging for transcatheter mitral valve replacement in the domestic sheep model
Published in Scientific reports (23-05-2024)“…Preclinical in vivo evaluation is an essential step in the progression of new cardiac devices into patient use, with studies predominantly performed in the…”
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Anisotropic Polytetrafluoroethylene Cardiovascular Conduits Spontaneously Expand in a Growing Lamb Model
Published in Journal of investigative surgery (01-12-2021)“…Insertion of conduits from the right ventricle (RV) to the pulmonary artery (PA) is a commonly used technique for repair of congenital heart defects. The vast…”
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3
New Model for the Assessment of Transcatheter Aortic Valve Replacement Devices in Sheep
Published in Journal of investigative surgery (01-02-2022)“…Transcatheter aortic valve replacement (TAVR) is an effective therapy in treating high-risk patients suffering from aortic stenosis. Animal models used to…”
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4
Feasibility Study of Catheter-Based Interventions for Anisotropic Expanded Polytetrafluoroethylene Cardiovascular Conduits in a Growing Lamb Model
Published in Journal of investigative surgery (01-11-2021)“…Cardiovascular repair in children often requires implant of conduits which do not have growth potential and will require reoperation. In the current study we…”
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5
Evaluation of an engineered vascular graft exhibiting somatic growth in lambs to model repair of absent pulmonary artery branch
Published in Communications medicine (16-10-2024)“…Background Growth is the holy grail of tissue implants in pediatrics. No vascular graft currently in use for surgical repairs of congenital heart defects has…”
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Out-of-Hospital Cardiac Arrest and Airborne Fine Particulate Matter: A Case-Crossover Analysis of Emergency Medical Services Data in Indianapolis, Indiana
Published in Environmental health perspectives (01-05-2008)“…Background: Previous studies have found particulate matter (PM) < 2.5 μm in aerodynamic diameter $({\rm PM}_{2.5})$ associated with heart disease mortality…”
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7
Pediatric tri-tube valved conduits made from fibroblast-produced extracellular matrix evaluated over 52 weeks in growing lambs
Published in Science translational medicine (17-03-2021)“…There is a need for replacement heart valves that can grow with children. We fabricated tubes of fibroblast-derived collagenous matrix that have been shown to…”
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Multi-omic and multispecies analysis of right ventricular dysfunction
Published in The Journal of heart and lung transplantation (01-02-2024)“…Right ventricular failure (RVF) is a leading cause of morbidity and mortality in multiple cardiovascular diseases, but there are no treatments for RVF as…”
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Porcine Model of the Arterial Switch Operation: Implications for Unique Strategies in the Management of Hypoplastic Left Ventricles
Published in Pediatric cardiology (01-03-2021)“…There are no reports on the performance of the arterial switch operation (ASO) in a normal heart with normally related great vessels. The objective of this…”
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10
Pilot study investigating the feasibility of mitral valve repair without aortic cross-clamping and cardioplegia
Published in Canadian journal of veterinary research (01-04-2020)“…There is evidence that perfusing the heart with a heart and lung machine is less injurious than cross-clamping the aorta and administering cardioplegia during…”
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Establishing Background Pathologic Changes of Valve Replacement Surgery in Sheep
Published in Cardiovascular engineering and technology (01-02-2022)“…Purpose Sheep are the standard preclinical model for assessing safety of novel replacement heart valves, yet the anatomic and pathologic effects of invasive…”
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12
The Hancock® Valved Conduit for Right Ventricular Outflow Tract Reconstruction in Sheep for Assessing New Devices
Published in The Journal of heart valve disease (01-07-2017)“…Xenograft conduits have been used successfully to repair congenital heart defects, but are prone to failure over time. Hence, in order to improve patient…”
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The Sheep as a Translational Model for Next Generation Valve Replacement Devices: A Multimodal Cardiac Imaging Study
Published 01-01-2024“…The development of catheter-based cardiac valve replacement devices, or transcatheter valves, has ushered in a new era in the treatment of patients with…”
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Dissertation -
14
Establishing Background Pathologic Changes of Mitral and Aortic Valve Replacement Using Sham Surgery in Sheep
Published in Structural heart (Online) (11-04-2019)Get full text
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Distribution of the Sensitivities to Penicillin of Types of Diplococcus pneumoniae in an American Indian Population
Published in The Journal of infectious diseases (01-07-1974)“…Pneumococci relatively insensitive to penicillin (minimal inhibitory concentration, ⩾ 0.1 µg/ml) were demonstrated in 14% of strains of Diplococcus pneumoniae…”
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16
California Government and Politics
Published in The Western Political Quarterly (01-12-1972)Get full text
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