Search Results - "Carnevale, Nicholas"
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Compartmentalization of GABAergic Inhibition by Dendritic Spines
Published in Science (American Association for the Advancement of Science) (10-05-2013)“…γ-aminobutyric acid-mediated (GABAergic) inhibition plays a critical role in shaping neuronal activity in the neocortex. Numerous experimental investigations…”
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Simulations predict differing phase responses to excitation vs. inhibition in theta-resonant pyramidal neurons
Published in Journal of neurophysiology (01-10-2023)“…Rhythmic activity is ubiquitous in neural systems, with theta-resonant pyramidal neurons integrating rhythmic inputs in many cortical structures. Impedance…”
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Electrical advantages of dendritic spines
Published in PloS one (20-04-2012)“…Many neurons receive excitatory glutamatergic input almost exclusively onto dendritic spines. In the absence of spines, the amplitudes and kinetics of…”
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Human Neocortical Neurosolver (HNN), a new software tool for interpreting the cellular and network origin of human MEG/EEG data
Published in eLife (22-01-2020)“…Magneto- and electro-encephalography (MEG/EEG) non-invasively record human brain activity with millisecond resolution providing reliable markers of healthy and…”
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Input of expressed hERG current into a complex neuron in silico cardiac atrial cell: Implications for cardiotoxicity screening
Published in Biophysical journal (10-02-2023)Get full text
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Effects of Ih and TASK-like shunting current on dendritic impedance in layer 5 pyramidal-tract neurons
Published in Journal of neurophysiology (01-04-2021)“…Pyramidal neurons in neocortex have complex input-output relationships that depend on their morphologies, ion channel distributions, and the nature of their…”
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Effects of I h and TASK-like shunting current on dendritic impedance in layer 5 pyramidal-tract neurons
Published in Journal of neurophysiology (01-04-2021)“…Pyramidal neurons in neocortex have complex input-output relationships that depend on their morphologies, ion channel distributions, and the nature of their…”
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Modernizing the NEURON Simulator for Sustainability, Portability, and Performance
Published in Frontiers in neuroinformatics (27-06-2022)“…The need for reproducible, credible, multiscale biological modeling has led to the development of standardized simulation platforms, such as the widely-used…”
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Cortical dendritic spine heads are not electrically isolated by the spine neck from membrane potential signals in parent dendrites
Published in Cerebral cortex (New York, N.Y. 1991) (01-02-2014)“…The evidence for an important hypothesis that cortical spine morphology might participate in modifying synaptic efficacy that underlies plasticity and possibly…”
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Neuron Names: A Gene- and Property-Based Name Format, With Special Reference to Cortical Neurons
Published in Frontiers in neuroanatomy (21-03-2019)“…Precision in neuron names is increasingly needed. We are entering a new era in which classical anatomical criteria are only the beginning toward defining the…”
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Early experiences in developing and managing the neuroscience gateway
Published in Concurrency and computation (01-02-2015)“…Summary The last few decades have seen the emergence of computational neuroscience as a mature field where researchers are interested in modeling complex and…”
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ModelDB: A Database to Support Computational Neuroscience
Published in Journal of computational neuroscience (01-07-2004)“…Wider dissemination and testing of computational models are crucial to the field of computational neuroscience. Databases are being developed to meet this…”
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Effects of low frequency electric fields on synaptic integration in hippocampal CA1 pyramidal neurons: implications for power line emissions
Published in Frontiers in cellular neuroscience (09-10-2014)“…The possible cognitive effects of low frequency external electric fields (EFs), such as those generated by power lines, are poorly understood. Their functional…”
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Functional Structure of the Mitral Cell Dendritic Tuft in the Rat Olfactory Bulb
Published in The Journal of neuroscience (09-04-2008)“…The input-output transform performed by mitral cells, the principal projection neurons of the olfactory bulb, is one of the key factors in understanding…”
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Passive Normalization of Synaptic Integration Influenced by Dendritic Architecture
Published in Journal of neurophysiology (01-12-1999)“… 1 Division of Life Sciences, University of Texas at San Antonio, San Antonio, Texas 78249; and 2 Department of Psychology, Yale University, New Haven,…”
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Abnormal Excitability of Oblique Dendrites Implicated in Early Alzheimer's: A Computational Study
Published in Frontiers in neural circuits (2010)“…The integrative properties of cortical pyramidal dendrites are essential to the neural basis of cognitive function, but the impact of amyloid beta protein…”
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Comparative Electrotonic Analysis of Three Classes of Rat Hippocampal Neurons
Published in Journal of neurophysiology (01-08-1997)“…Nicholas T. Carnevale 1 , 2 , Kenneth Y. Tsai 1 , 2 , Brenda J. Claiborne 4 , and Thomas H. Brown 1 , 2 , 3 1 Center for Theoretical and Applied Neuroscience,…”
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Electrical behaviour of dendritic spines as revealed by voltage imaging
Published in Nature communications (05-10-2015)“…Thousands of dendritic spines on individual neurons process information and mediate plasticity by generating electrical input signals using a sophisticated…”
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Interfacing a real-time dynamic clamp system with neuron simulation software in living cells
Published in Biophysical journal (11-02-2022)Get full text
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Neuroscience Gateway Cyberinfrastructure Providing Supercomputing Resources for Large Scale Computational Neuroscience Research
Published in Frontiers in neuroinformatics (2016)“…Abstract only…”
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