Search Results - "Carneiro, Leticia A.M"

Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense Program by Tattoli, Ivan, Sorbara, Matthew T., Vuckovic, Dajana, Ling, Arthur, Soares, Fraser, Carneiro, Leticia A.M., Yang, Chloe, Emili, Andrew, Philpott, Dana J., Girardin, Stephen E.

“…Autophagy, which targets cellular constituents for degradation, is normally inhibited in metabolically replete cells by the metabolic checkpoint kinase mTOR…”
Get full text

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry by Jones, Nicola L, Philpott, Dana J, Soares, Fraser, Nuñez, Gabriel, Carneiro, Leticia A M, Yuan, Linda, Girardin, Stephen E, Le Bourhis, Lionel, Chea, Evelyn, Travassos, Leonardo H, Hussey, Seamus, Kim, Yun-Gi, Magalhães, João G, Allaoui, Abdelmounaaim, Ramjeet, Mahendrasingh, Boneca, Ivo G

“…Autophagy facilitates host defense against invading bacteria. Philpott and colleagues show that Nod1 and Nod2 link pathogen sensing to autophagy by recruiting…”
Get full text

Nod proteins link bacterial sensing and autophagy by Travassos, Leonardo H., Carneiro, Leticia A.M., Girardin, Stephen, Philpott, Dana J.

“…Autophagy is one of the main cellular degradation systems in eukaryotes, being responsible for the elimination of long-lived proteins and damaged organelles…”
Get full text

Nod1 Participates in the Innate Immune Response to Pseudomonas aeruginosa by Travassos, Leonardo H., Carneiro, Leticia A.M., Girardin, Stephen E., Boneca, Ivo G., Lemos, Ramon, Bozza, Marcelo T., Domingues, Regina C.P., Coyle, Anthony J., Bertin, John, Philpott, Dana J., Plotkowski, Maria Cristina

“…The mammalian innate immune system recognizes pathogen-associated molecular patterns through pathogen recognition receptors. Nod1 has been described recently…”
Get full text

Does acute exposure to aldehydes impair pulmonary function and structure? by Abreu, Mariana de, Neto, Alcendino Cândido, Carvalho, Giovanna, Casquillo, Natalia Vasconcelos, Carvalho, Niedja, Okuro, Renata, Ribeiro, Gabriel C.Motta, Machado, Mariana, Cardozo, Aléxia, Silva, Aline Santos e, Barboza, Thiago, Vasconcellos, Luiz Ricardo, Rodrigues, Danielle Araujo, Camilo, Luciana, Carneiro, Leticia de A.M, Jandre, Frederico, Pino, Alexandre V, Giannella-Neto, Antonio, Zin, Walter A, Corrêa, Leonardo Holanda Travassos, Souza, Marcio Nogueira de, Carvalho, Alysson R

“…Highlights • As alcohol is used as fuel, the concentrations of aldehydes increase in air. • Acetaldehyde and formaldehyde are the most common aldehydes in…”
Get full text

The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling by Abdel-Nour, Mena, Carneiro, Leticia A M, Downey, Jeffrey, Tsalikis, Jessica, Outlioua, Ahmed, Prescott, Dave, Da Costa, Leandro Silva, Hovingh, Elise S, Farahvash, Armin, Gaudet, Ryan G, Molinaro, Raphael, van Dalen, Rob, Lau, Charles C Y, Azimi, Farshad C, Escalante, Nichole K, Trotman-Grant, Aaron, Lee, Jeffrey E, Gray-Owen, Scott D, Divangahi, Maziar, Chen, Jane-Jane, Philpott, Dana J, Arnoult, Damien, Girardin, Stephen E

“…Multiple cytosolic innate sensors form large signalosomes after activation, but this assembly needs to be tightly regulated to avoid accumulation of misfolded…”
Get full text

Autophagy and viral diseases transmitted by Aedes aegypti and Aedes albopictus by Carneiro, Leticia A.M., Travassos, Leonardo H.

“…Despite a long battle that was started by Oswaldo Cruz more than a century ago, in 1903, Brazil still struggles to fight Aedes aegypti and Aedes albopictus,…”
Get full text

Protein aggregation as a cellular response to oxidative stress induced by heme and iron by Vasconcellos, Luiz R. C., Dutra, Fabianno F., Siqueira, Mariana S., Paula-Neto, Heitor A., Dahan, Jennifer, Kiarely, Ellen, Carneiro, Leticia A. M., Bozza, Marcelo T., Travassos, Leonardo H.

“…Hemolytic diseases include a variety of conditions with diverse etiologies in which red blood cells are destroyed and large amounts of hemeproteins are…”
Get full text

Shigella Induces Mitochondrial Dysfunction and Cell Death in Nonmyleoid Cells by Carneiro, Leticia A.M., Travassos, Leonardo H., Soares, Fraser, Tattoli, Ivan, Magalhaes, Joao G., Bozza, Marcelo T., Plotkowski, Maria C., Sansonetti, Philippe J., Molkentin, Jeffery D., Philpott, Dana J., Girardin, Stephen E.

Get full text

Heme and iron induce protein aggregation by Travassos, Leonardo H., Vasconcellos, Luiz R. C., Bozza, Marcelo T., Carneiro, Leticia A. M.

“…Heme is an essential molecule expressed in many tissues where it plays key roles as the prosthetic group of several proteins involved in vital physiological…”
Get full text

The Unfolded Protein Response and Autophagy on the Crossroads of Coronaviruses Infections by Prestes, Elisa B, Bruno, Julia C P, Travassos, Leonardo H, Carneiro, Leticia A M

“…The ability to sense and adequately respond to variable environmental conditions is central for cellular and organismal homeostasis. Eukaryotic cells are…”
Get full text

Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells by Carneiro, Leticia A M, Travassos, Leonardo H, Soares, Fraser, Tattoli, Ivan, Magalhaes, Joao G, Bozza, Marcelo T, Plotkowski, Maria C, Sansonetti, Philippe J, Molkentin, Jeffery D, Philpott, Dana J, Girardin, Stephen E

“…Shigella rapidly kills myeloid cells via a caspase-1 inflammasome-dependent cell death mechanism. However, despite a critical role for nonmyeloid cells in the…”
Get full text

Nod1 Detects a Unique Muropeptide from Gram-Negative Bacterial Peptidoglycan by Girardin, Stephen E., Boneca, Ivo G., Leticia A. M. Carneiro, Antignac, Aude, Jéhanno, Muguette, Viala, Jérôme, Tedin, Karsten, Taha, Muhamed-Kheir, Labigne, Agnès, Zähringer, Ulrich, Coyle, Anthony J., DiStefano, Peter S., Bertin, John, Sansonetti, Philippe J., Philpott, Dana J.

“…Although the role of Toll-like receptors in extracellular bacterial sensing has been investigated intensively, intracellular detection of bacteria through Nod…”
Get full text

Editorial: Producing, Sensing and Responding to Cellular Stress in Immunity by Paula-Neto, Heitor A, Pereira, Renata M, Carneiro, Leticia A M

Get full text

Post-transcriptional Inhibition of Luciferase Reporter Assays by the Nod-like Receptor Proteins NLRX1 and NLRC3 by Ling, Arthur, Soares, Fraser, Croitoru, David O., Tattoli, Ivan, Carneiro, Leticia A.M., Boniotto, Michele, Benko, Szilvia, Philpott, Dana J., Girardin, Stephen E.

“…Luciferase reporter assays (LRAs) are widely used to assess the activity of specific signal transduction pathways. Although powerful, rapid and convenient,…”
Get full text

The Interplay between NLRs and Autophagy in Immunity and Inflammation by Carneiro, Leticia A M, Travassos, Leonardo H

“…Since they were first described as cytosolic sensors of microbial molecules a decade ago, the Nod-like receptors (NLRs) have been shown to have many different…”
Get full text

Fungal surface and innate immune recognition of filamentous fungi by Figueiredo, Rodrigo T, Carneiro, Leticia A M, Bozza, Marcelo T

“…The innate immune system performs specific detection of molecules from infectious agents through pattern recognition receptors. This recognition triggers…”
Get full text

Nod-like receptors in innate immunity and inflammatory diseases by Carneiro, Leticia A M, Travassos, Leonardo H, Girardin, Stephen E

“…Over the past few years the field of innate immunity has undergone a revolution with the discovery of pattern recognition molecules (PRM) and their role in…”
Get more information

Integrated Stress Responses to Bacterial Pathogenesis Patterns by Rodrigues, Larissa O C P, Graça, Rodrigo S F, Carneiro, Leticia A M

“…Activation of an appropriate innate immune response to bacterial infection is critical to limit microbial spread and generate cytokines and chemokines to…”
Get full text

Antimicrobial-resistance and enterotoxin-encoding genes among staphylococci isolated from expressed human breast milk by Carneiro, Leticia A.M, Queiroz, Mara L.P, Merquior, Vania L.C

“…Disciplina de Microbiologia e Imunologia, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Avenida 28 de Setembro, 87, Fundos – 3o…”
Get full text