Search Results - "Carneiro, Letı́cia A.M"
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Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense Program
Published in Cell host & microbe (14-06-2012)“…Autophagy, which targets cellular constituents for degradation, is normally inhibited in metabolically replete cells by the metabolic checkpoint kinase mTOR…”
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Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
Published in Nature immunology (01-01-2010)“…Autophagy facilitates host defense against invading bacteria. Philpott and colleagues show that Nod1 and Nod2 link pathogen sensing to autophagy by recruiting…”
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Nod proteins link bacterial sensing and autophagy
Published in Autophagy (01-04-2010)“…Autophagy is one of the main cellular degradation systems in eukaryotes, being responsible for the elimination of long-lived proteins and damaged organelles…”
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Nod1 Participates in the Innate Immune Response to Pseudomonas aeruginosa
Published in The Journal of biological chemistry (04-11-2005)“…The mammalian innate immune system recognizes pathogen-associated molecular patterns through pathogen recognition receptors. Nod1 has been described recently…”
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Does acute exposure to aldehydes impair pulmonary function and structure?
Published in Respiratory physiology & neurobiology (15-07-2016)“…Highlights • As alcohol is used as fuel, the concentrations of aldehydes increase in air. • Acetaldehyde and formaldehyde are the most common aldehydes in…”
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Antimicrobial-resistance and enterotoxin-encoding genes among staphylococci isolated from expressed human breast milk
Published in Journal of medical microbiology (01-08-2004)“…Disciplina de Microbiologia e Imunologia, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Avenida 28 de Setembro, 87, Fundos 3o…”
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The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling
Published in Science (American Association for the Advancement of Science) (05-07-2019)“…Multiple cytosolic innate sensors form large signalosomes after activation, but this assembly needs to be tightly regulated to avoid accumulation of misfolded…”
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Antimicrobial resistance in Gram-negative bacilli isolated from infant formulas
Published in FEMS microbiology letters (21-11-2003)“…A total of 90 samples of infant formula (IF) were collected from the lactary of a teaching hospital, during a 4-month period from July to August 1999. The…”
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Autophagy and viral diseases transmitted by Aedes aegypti and Aedes albopictus
Published in Microbes and infection (01-03-2016)“…Despite a long battle that was started by Oswaldo Cruz more than a century ago, in 1903, Brazil still struggles to fight Aedes aegypti and Aedes albopictus,…”
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Protein aggregation as a cellular response to oxidative stress induced by heme and iron
Published in Proceedings of the National Academy of Sciences - PNAS (22-11-2016)“…Hemolytic diseases include a variety of conditions with diverse etiologies in which red blood cells are destroyed and large amounts of hemeproteins are…”
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Shigella Induces Mitochondrial Dysfunction and Cell Death in Nonmyleoid Cells
Published in Cell host & microbe (01-02-2009)Get full text
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Heme and iron induce protein aggregation
Published in Autophagy (04-03-2017)“…Heme is an essential molecule expressed in many tissues where it plays key roles as the prosthetic group of several proteins involved in vital physiological…”
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The Unfolded Protein Response and Autophagy on the Crossroads of Coronaviruses Infections
Published in Frontiers in cellular and infection microbiology (28-04-2021)“…The ability to sense and adequately respond to variable environmental conditions is central for cellular and organismal homeostasis. Eukaryotic cells are…”
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Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells
Published in Cell host & microbe (19-02-2009)“…Shigella rapidly kills myeloid cells via a caspase-1 inflammasome-dependent cell death mechanism. However, despite a critical role for nonmyeloid cells in the…”
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Nod1 Detects a Unique Muropeptide from Gram-Negative Bacterial Peptidoglycan
Published in Science (American Association for the Advancement of Science) (06-06-2003)“…Although the role of Toll-like receptors in extracellular bacterial sensing has been investigated intensively, intracellular detection of bacteria through Nod…”
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Editorial: Producing, Sensing and Responding to Cellular Stress in Immunity
Published in Frontiers in immunology (06-09-2019)Get full text
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Post-transcriptional Inhibition of Luciferase Reporter Assays by the Nod-like Receptor Proteins NLRX1 and NLRC3
Published in The Journal of biological chemistry (17-08-2012)“…Luciferase reporter assays (LRAs) are widely used to assess the activity of specific signal transduction pathways. Although powerful, rapid and convenient,…”
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The Interplay between NLRs and Autophagy in Immunity and Inflammation
Published in Frontiers in immunology (01-01-2013)“…Since they were first described as cytosolic sensors of microbial molecules a decade ago, the Nod-like receptors (NLRs) have been shown to have many different…”
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Fungal surface and innate immune recognition of filamentous fungi
Published in Frontiers in microbiology (01-01-2011)“…The innate immune system performs specific detection of molecules from infectious agents through pattern recognition receptors. This recognition triggers…”
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Nod-like receptors in innate immunity and inflammatory diseases
Published in Annals of medicine (Helsinki) (2007)“…Over the past few years the field of innate immunity has undergone a revolution with the discovery of pattern recognition molecules (PRM) and their role in…”
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