Search Results - "Carneiro, Ana M. D"

Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes by Carneiro, Ana M.D, Airey, David C, Thompson, Brent, Zhu, Chong-Bin, Lu, Lu, Chesler, Elissa J, Erikson, Keith M, Blakely, Randy D

“…The human serotonin (5-hydroxytryptamine, 5-HT) transporter (hSERT, SLC6A4) figures prominently in the etiology and treatment of many prevalent neurobehavioral…”
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Differential Regulation of Adhesion and Phagocytosis of Resting and Activated Microglia by Dopamine by Fan, Yang, Chen, Zhilu, Pathak, Janak L, Carneiro, Ana M D, Chung, Chang Y

“…Microglia, the immune competent cells of the central nervous system (CNS), normally exist in a resting state characterized by a ramified morphology with many…”
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Integrin αVβ3 Function Influences Citalopram Immobility Behavior in the Tail Suspension Test by Pan, Hope, Dohn, Michael R, Kingston, Rody, Carneiro, Ana M D

“…Human studies first identified genetic and expression interactions between integrin β3 and serotonin (5-HT) transporter (SERT) genes. This association has been…”
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The Gain-of-Function Integrin β3 Pro33 Variant Alters the Serotonin System in the Mouse Brain by Dohn, Michael R, Kooker, Christopher G, Bastarache, Lisa, Jessen, Tammy, Rinaldi, Capria, Varney, Seth, Mazalouskas, Matthew D, Pan, Hope, Oliver, Kendra H, Velez Edwards, Digna R, Sutcliffe, James S, Denny, Joshua C, Carneiro, Ana M D

“…Engagement of integrins by the extracellular matrix initiates signaling cascades that drive a variety of cellular functions, including neuronal migration and…”
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Single molecule analysis of serotonin transporter regulation using antagonist-conjugated quantum dots reveals restricted, p38 MAPK-dependent mobilization underlying uptake activation by Chang, Jerry C, Tomlinson, Ian D, Warnement, Michael R, Ustione, Alessandro, Carneiro, Ana M D, Piston, David W, Blakely, Randy D, Rosenthal, Sandra J

“…The presynaptic serotonin (5-HT) transporter (SERT) is targeted by widely prescribed antidepressant medications. Altered SERT expression or regulation has been…”
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Absence of preference for social novelty and increased grooming in integrin β3 knockout mice: Initial studies and future directions by Carter, Michelle D., Shah, Charisma R., Muller, Christopher L., Crawley, Jacqueline N., Carneiro, Ana M. D., Veenstra-VanderWeele, Jeremy

“…Elevated whole blood serotonin 5‐HT, or hyperserotonemia, is a common biomarker in autism spectrum disorder (ASD). The integrin β3 receptor subunit gene…”
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Serotonin transporter and integrin beta 3 genes interact to modulate serotonin uptake in mouse brain by Whyte, Alonzo, Jessen, Tammy, Varney, Seth, Carneiro, Ana M.D.

“…•Epistatic interaction between Slc6a4 and Itgb3 in the modulation of the serotonin system.•Slc6a4 heterozygosity dictates SERT expression in midbrain…”
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Minocycline alleviates depression-like symptoms by rescuing decrease in neurogenesis in dorsal hippocampus via blocking microglia activation/phagocytosis by Bassett, Ben, Subramaniyam, Selvaraj, Fan, Yang, Varney, Seth, Pan, Hope, Carneiro, Ana M.D., Chung, Chang Y.

“…•Minocycline ameliorate chronic mild stress-induced depressive behaviors.•We found a correlation between presence of phagocytic microglia and loss of…”
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Whole Blood Serotonin Levels and Platelet 5-HT2A Binding in Autism Spectrum Disorder by Aaron, Elizabeth, Montgomery, Alicia, Ren, Xinguo, Guter, Stephen, Anderson, George, Carneiro, Ana M. D., Jacob, Suma, Mosconi, Matthew, Pandey, Ghanshyam N., Cook, Edwin, Veenstra-VanderWeele, Jeremy

“…Elevated whole blood serotonin (WB5-HT) is a well-replicated biomarker in autism spectrum disorder (ASD). Decreased platelet serotonin receptor 5-HT 2A binding…”
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Integrin beta 3 Haploinsufficiency Modulates Serotonin Transport and Antidepressant-Sensitive Behavior in Mice by Mazalouskas, Matthew, Jessen, Tammy, Varney, Seth, Sutcliffe, James S, Veenstra-VanderWeele, Jeremy, Cook, Edwin H, Carneiro, Ana M D

“…Converging lines of evidence have identified genetic interactions between the serotonin transporter (SERT) gene and ITGB3, which encodes the beta 3 subunit…”
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Adrenal serotonin derives from accumulation by the antidepressant-sensitive serotonin transporter by Brindley, Rebecca L., Bauer, Mary Beth, Walker, L. Anne, Quinlan, Meagan A., Carneiro, Ana M.D., Sze, Ji-Ying, Blakely, Randy D., Currie, Kevin P.M.

“…[Display omitted] Adrenal chromaffin cells comprise the neuroendocrine arm of the sympathetic nervous system and secrete catecholamines to coordinate the…”
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Loss of Serotonin Transporter Function Alters ADP-mediated Glycoprotein αIIbβ3 Activation through Dysregulation of the 5-HT2A Receptor by Oliver, Kendra H., Duvernay, Matthew T., Hamm, Heidi E., Carneiro, Ana M.D.

“…Reduced platelet aggregation and a mild bleeding phenotype have been observed in patients chronically taking selective serotonin reuptake inhibitors (SSRIs)…”
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The emerging role of integrins in neuropsychiatric disorders by Carneiro, Ana M D

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Whole Blood Serotonin Levels and Platelet 5-HT.sub.2A Binding in Autism Spectrum Disorder by Aaron, Elizabeth, Montgomery, Alicia, Ren, Xinguo, Guter, Stephen, Anderson, George, Carneiro, Ana M. D, Jacob, Suma

“…Elevated whole blood serotonin (WB5-HT) is a well-replicated biomarker in autism spectrum disorder (ASD). Decreased platelet serotonin receptor 5-HT.sub.2A…”
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Loss of serotonin transporter function alters ADP‐mediated αIIbβ3 activation through disregulation of 5HT 2A receptor by Oliver, Kendra H, Hamm, Heidi, Carneiro, Ana M. D.

“…Abstract only Clinical observations indicate that patients taking selective serotonin reuptake inhibitors (SSRIs) have an increased risk of bleeding. However…”
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Whole Blood Serotonin Levels and Platelet 5-HT[subscript 2A] Binding in Autism Spectrum Disorder by Aaron, Elizabeth, Montgomery, Alicia, Ren, Xinguo, Guter, Stephen, Anderson, George, Carneiro, Ana M. D, Jacob, Suma, Mosconi, Matthew, Pandey, Ghanshyam N, Cook, Edwin, Veenstra-VanderWeele, Jeremy

“…Elevated whole blood serotonin (WB5-HT) is a well-replicated biomarker in autism spectrum disorder (ASD). Decreased platelet serotonin receptor 5-HT[subscript…”
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Integrin β3 Haploinsufficiency Modulates Serotonin Transport and Antidepressant-Sensitive Behavior in Mice by Mazalouskas, Matthew, Jessen, Tammy, Varney, Seth, Sutcliffe, James S, Veenstra-VanderWeele, Jeremy, Cook, Jr, Edwin H, Carneiro, Ana M D

“…Converging lines of evidence have identified genetic interactions between the serotonin transporter (SERT) gene and ITGB3, which encodes the β3 subunit that…”
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Integrin [beta]3 Haploinsufficiency Modulates Serotonin Transport and Antidepressant-Sensitive Behavior in Mice by Mazalouskas, Matthew, Jessen, Tammy, Varney, Seth, Sutcliffe, James S, Veenstra-vanderweele, Jeremy, Cook, Edwin H, Carneiro, Ana M D

“…Converging lines of evidence have identified genetic interactions between the serotonin transporter (SERT) gene and ITGB3, which encodes the β3 subunit that…”
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Whole Blood Serotonin Levels and Platelet 5-HT 2A Binding in Autism Spectrum Disorder by Aaron, Elizabeth, Montgomery, Alicia, Ren, Xinguo, Guter, Stephen, Anderson, George, Carneiro, Ana M D, Jacob, Suma, Mosconi, Matthew, Pandey, Ghanshyam N, Cook, Edwin, Veenstra-VanderWeele, Jeremy

“…Elevated whole blood serotonin (WB5-HT) is a well-replicated biomarker in autism spectrum disorder (ASD). Decreased platelet serotonin receptor 5-HT binding…”
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Pharmacological rescue of serotonin transporter inactivation by the autism‐associated integrin b3 Pro33 coding variant by Carneiro, Ana MD, Dohn, Michael, Jessen, Tammy, Edwards, Digna Velez, Danny, Joshua, Sutcliffe, James

“…Abstract only Cell adhesion to the extracellular matrix (ECM) is mediated by integrins, heterodimeric transmembrane proteins that comprise a family of 18 α and…”
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