Search Results - "Carmona, Marcos Plana"
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Single cell RNA-seq identifies the origins of heterogeneity in efficient cell transdifferentiation and reprogramming
Published in eLife (12-03-2019)“…Forced transcription factor expression can transdifferentiate somatic cells into other specialised cell types or reprogram them into induced pluripotent stem…”
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2
CEBPA phase separation links transcriptional activity and 3D chromatin hubs
Published in Cell reports (Cambridge) (29-08-2023)“…Cell identity is orchestrated through an interplay between transcription factor (TF) action and genome architecture. The mechanisms used by TFs to shape…”
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3
Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity
Published in eLife (27-06-2023)“…Here, we describe how the speed of C/EBPα-induced B cell to macrophage transdifferentiation (BMT) can be regulated, using both mouse and human models. The…”
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From research to rapid response: mass COVID-19 testing by volunteers at the Centre for Genomic Regulation [version 1; peer review: 2 approved]
Published in F1000 research (2020)“…The COVID-19 pandemic has posed and is continuously posing enormous societal and health challenges worldwide. The research community has mobilized to develop…”
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5
Cardiopharyngeal deconstruction and ancestral tunicate sessility
Published in Nature (London) (18-11-2021)“…A central question in chordate evolution is the origin of sessility in adult ascidians, and whether the appendicularian complete free-living style represents a…”
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Carm1-arginine methylation of the transcription factor C/EBP[alpha] regulates transdifferentiation velocity
Published in eLife (27-06-2023)“…Here, we describe how the speed of C/EBP[alpha]-induced B cell to macrophage transdifferentiation (BMT) can be regulated, using both mouse and human models…”
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7
The trophectoderm acts as a niche for the inner cell mass through C/EBPα-regulated IL-6 signaling
Published in Stem cell reports (13-09-2022)“…IL-6 has been shown to be required for somatic cell reprogramming into induced pluripotent stem cells (iPSCs). However, how Il6 expression is regulated and…”
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