Search Results - "Carmona, Eva"
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COVID-19 Transmission, Current Treatment, and Future Therapeutic Strategies
Published in Molecular pharmaceutics (01-03-2021)“…At the stroke of the New Year 2020, COVID-19, a zoonotic disease that would turn into a global pandemic, was identified in the Chinese city of Wuhan. Although…”
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The Role of Infection in Interstitial Lung Diseases: A Review
Published in Chest (01-10-2017)“…Interstitial lung disease (ILD) comprises an array of heterogeneous parenchymal lung diseases that are associated with a spectrum of pathologic, radiologic,…”
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Macrophage PPAR-γ suppresses long-term lung fibrotic sequelae following acute influenza infection
Published in PloS one (04-10-2019)“…Influenza virus causes a heterogeneous respiratory infectious disease ranging from self-limiting symptoms to non-resolving pathology in the lungs. Worldwide,…”
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Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice. An Official American Thoracic Society Clinical Practice Guideline
Published in American journal of respiratory and critical care medicine (01-09-2019)“…Fungal infections are of increasing incidence and importance in immunocompromised and immunocompetent patients. Timely diagnosis relies on appropriate use of…”
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36-Year-Old Woman With Progressive Dyspnea, Cough, and Chills
Published in Mayo Clinic proceedings (01-01-2024)Get full text
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Overview of Treatment Approaches for Fungal Infections
Published in Clinics in chest medicine (01-09-2017)“…Invasive fungal diseases cause high morbidity and mortality in an immunocompromised host. Antifungals are the drugs of choice and can be divided in 4 main…”
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When the Third Time Is Not the Charm—Trial Outcomes in Idiopathic Pulmonary Fibrosis
Published in JAMA : the journal of the American Medical Association (06-08-2024)Get full text
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Epidemiology of Sarcoidosis 1946-2013: A Population-Based Study
Published in Mayo Clinic proceedings (01-02-2016)“…To characterize the epidemiology of sarcoidosis from 1946 through 2013. An inception cohort of patients with incident sarcoidosis from January 1, 1976, through…”
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Targeting host tyrosine kinase receptor EphA2 signaling via small-molecule ALW-II-41-27 inhibits macrophage pro-inflammatory signaling responses to Pneumocystis carinii β-glucans
Published in Antimicrobial agents and chemotherapy (07-02-2024)“…the fungus that causes pneumonia (PJP), is a leading cause of morbidity and mortality in immunocompromised individuals. We have previously shown that lung…”
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Characterization of the Pneumocystis jirovecii and Pneumocystis murina phosphoglucomutases (Pgm2s): a potential target for Pneumocystis therapy
Published in Antimicrobial agents and chemotherapy (06-03-2024)“…cyst life forms contain abundant β-glucan carbohydrates, synthesized using β-1,3 and β-1,6 glucan synthase enzymes and the donor uridine diphosphate…”
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Pneumocystis Pneumonia in Patients Treated With Rituximab
Published in Chest (01-07-2013)“…Background Pneumocystis pneumonia (PcP) is an opportunistic fungal infection. Although T-cell immunity is classically related to Pneumocystis defense, recent…”
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EphA2 Is a Lung Epithelial Cell Receptor for Pneumocystis β-Glucans
Published in The Journal of infectious diseases (01-02-2022)“…Abstract Pneumocystis species interaction with myeloid cells is well known, especially in macrophages; however, how the organism binds to lung epithelial cells…”
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Diagnostic Utility of Angiotensin-Converting Enzyme in Sarcoidosis: A Population-Based Study
Published in Lung (01-02-2016)“…Purpose Sarcoidosis is a disease with heterogenous clinical presentations. Diagnosis of sarcoidosis is often challenging with the lack of gold standard tests…”
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48-Year-Old Man With Bilateral Mediastinal Lymphadenopathy, Orbital Pseudotumors, Kidney Masses, and Acute Pancreatitis
Published in Mayo Clinic proceedings (01-03-2019)“…A 48-year-old man with a history of chronic rhinosinusitis, gastroesophageal reflux disease, and dietcontrolled non-insulin-dependent diabetes mellitus…”
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Gene expression in lung epithelial cells following interaction with Pneumocystis carinii and its specific life forms yields insights into host gene responses to infection
Published in Microbiology and immunology (01-05-2022)“…Pneumocystis spp. interacts with epithelial cells in the alveolar spaces of the lung. It is thought that the binding of Pneumocystis to host cell epithelium is…”
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CLEC4A and CLEC12B C-type lectin receptors mediate interactions with Pneumocystis cell wall components
Published in Journal of medical microbiology (01-06-2023)“…C-type lectin receptors (CLRs) are prominently expressed on myeloid cells where they perform multiple functions including serving as pattern recognition…”
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Targeting CARD9 with Small-Molecule Therapeutics Inhibits Innate Immune Signaling and Inflammatory Response to Pneumocystis carinii β-Glucans
Published in Antimicrobial agents and chemotherapy (20-10-2020)“…, the opportunistic fungus that causes pneumonia (PCP) in humans, is a significant contributor to morbidity and mortality in immunocompromised patients. Given…”
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Pulmonary Sarcoidosis: Diagnosis and Treatment
Published in Mayo Clinic proceedings (01-07-2016)“…Abstract Sarcoidosis is a chronic granulomatous disease of unknown cause that is seen worldwide and occurs mainly in patients between the ages of 20 and 60…”
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Physiological predictors of survival in patients with sarcoidosis-associated pulmonary hypertension: results from an international registry
Published in The European respiratory journal (01-05-2020)“…Sarcoidosis-associated pulmonary hypertension (SAPH) is associated with reduced survival in single-centre studies. The international Registry for SAPH (ReSAPH)…”
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Canonical Stimulation of the NLRP3 Inflammasome by Fungal Antigens Links Innate and Adaptive B-Lymphocyte Responses by Modulating IL-1β and IgM Production
Published in Frontiers in immunology (09-11-2017)“…The NLRP3 inflammasome is activated in response to different bacterial, viral, and fungal pathogens and serves as modulator of different pattern recognition…”
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