Search Results - "Carmichael, Gordon G"

Long Noncoding RNAs with snoRNA Ends by Yin, Qing-Fei, Yang, Li, Zhang, Yang, Xiang, Jian-Feng, Wu, Yue-Wei, Carmichael, Gordon G., Chen, Ling-Ling

“…We describe the discovery of sno-lncRNAs, a class of nuclear-enriched intron-derived long noncoding RNAs (lncRNAs) that are processed on both ends by the…”
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Altered Nuclear Retention of mRNAs Containing Inverted Repeats in Human Embryonic Stem Cells: Functional Role of a Nuclear Noncoding RNA by Chen, Ling-Ling, Carmichael, Gordon G.

“…In many cells, mRNAs containing inverted repeats (Alu repeats in humans) in their 3′ untranslated regions (3′UTRs) are inefficiently exported to the cytoplasm…”
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Distinct Processing of lncRNAs Contributes to Non-conserved Functions in Stem Cells by Guo, Chun-Jie, Ma, Xu-Kai, Xing, Yu-Hang, Zheng, Chuan-Chuan, Xu, Yi-Feng, Shan, Lin, Zhang, Jun, Wang, Shaohua, Wang, Yangming, Carmichael, Gordon G., Yang, Li, Chen, Ling-Ling

“…Long noncoding RNAs (lncRNAs) evolve more rapidly than mRNAs. Whether conserved lncRNAs undergo conserved processing, localization, and function remains…”
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Decoding the function of nuclear long non-coding RNAs by Chen, Ling-Ling, Carmichael, Gordon G

“…Long non-coding RNAs (lncRNAs) are mRNA-like, non-protein-coding RNAs that are pervasively transcribed throughout eukaryotic genomes. Rather than silently…”
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H19 lncRNA Promotes Skeletal Muscle Insulin Sensitivity in Part by Targeting AMPK by Geng, Tingting, Liu, Ya, Xu, Yetao, Jiang, Ying, Zhang, Na, Wang, Zhangsheng, Carmichael, Gordon G, Taylor, Hugh S, Li, Da, Huang, Yingqun

“…Skeletal muscle plays a pivotal role in regulating systemic glucose homeostasis in part through the conserved cellular energy sensor AMPK. AMPK activation…”
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Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform by Da Li, Cao, Tiefeng, Sun, Xiaoli, Jin, Sungho, Di Xie, Huang, Xinmei, Yang, Xiaoyong, Carmichael, Gordon G., Taylor, Hugh S., Diano, Sabrina, Huang, Yingqun

“…Precise control of hepatic glucose production (HGP) is pivotal to maintain systemic glucose homeostasis. HNF4α functions to stimulate transcription of key…”
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TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons by Xie, Di, Stutz, Bernardo, Li, Feng, Chen, Fan, Lv, Haining, Sestan-Pesa, Matija, Catarino, Jonatas, Gu, Jianlei, Zhao, Hongyu, Stoddard, Christopher E, Carmichael, Gordon G, Shanabrough, Marya, Taylor, Hugh S, Liu, Zhong-Wu, Gao, Xiao- Bing, Horvath, Tamas L, Huang, Yingqun

“…The TET family of dioxygenases promote DNA demethylation by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). Hypothalamic agouti-related…”
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CIRCexplorer3: A CLEAR Pipeline for Direct Comparison of Circular and Linear RNA Expression by Ma, Xu-Kai, Wang, Meng-Ran, Liu, Chu-Xiao, Dong, Rui, Carmichael, Gordon G., Chen, Ling-Ling, Yang, Li

“…Sequences of circular RNAs (circRNAs) produced from back-splicing of exon(s) completely overlap with those from cognate linear RNAs transcribed from the same…”
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Prader-Willi syndrome: reflections on seminal studies and future therapies by Chung, Michael S, Langouët, Maéva, Chamberlain, Stormy J, Carmichael, Gordon G

“…Prader-Willi syndrome (PWS) is caused by the loss of function of the paternally inherited 15q11-q13 locus. This region is governed by genomic imprinting, a…”
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Gene regulation by SINES and inosines: biological consequences of A-to-I editing of Alu element inverted repeats by Chen, Ling-Ling, Carmichael, Gordon G.

“…The Alu elements are conserved ~300 nucleotide long repeat sequences that belong to the SINE family of retrotransposons found abundantly in primate genomes…”
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Long noncoding RNAs in mammalian cells: what, where, and why? by Chen, Ling-Ling, Carmichael, Gordon G.

“…Not all long, polyadenylated cellular RNAs encode polypeptides. In recent years, it has become apparent that a number of organisms express abundant amounts of…”
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Gene Regulation and Quality Control in Murine Polyomavirus Infection by Carmichael, Gordon G

“…Murine polyomavirus (MPyV) infects mouse cells and is highly oncogenic in immunocompromised hosts and in other rodents. Its genome is a small, circular DNA…”
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Global Analysis of Mouse Polyomavirus Infection Reveals Dynamic Regulation of Viral and Host Gene Expression and Promiscuous Viral RNA Editing by Garren, Seth B, Kondaveeti, Yuvabharath, Duff, Michael O, Carmichael, Gordon G

“…Mouse polyomavirus (MPyV) lytically infects mouse cells, transforms rat cells in culture, and is highly oncogenic in rodents. We have used deep sequencing to…”
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Effects of Length and Location on the Cellular Response to Double-Stranded RNA by Wang, Qiaoqiao, Carmichael, Gordon G

“…Article Usage Stats Services MMBR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Long noncoding RNAs in imprinting and X chromosome inactivation by Autuoro, Joseph M, Pirnie, Stephan P, Carmichael, Gordon G

“…The field of long noncoding RNA (lncRNA) research has been rapidly advancing in recent years. Technological advancements and deep-sequencing of the…”
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Dynamic Imaging of RNA in Living Cells by CRISPR-Cas13 Systems by Yang, Liang-Zhong, Wang, Yang, Li, Si-Qi, Yao, Run-Wen, Luan, Peng-Fei, Wu, Huang, Carmichael, Gordon G., Chen, Ling-Ling

“…Visualizing the location and dynamics of RNAs in live cells is key to understanding their function. Here, we identify two endonuclease-deficient,…”
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Antisense RNA: Function and Fate of Duplex RNA in Cells of Higher Eukaryotes by KUMAR, M, CARMICHAEL, G. G

“…Article Usage Stats Services MMBR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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High-throughput and site-specific identification of 2'- O -methylation sites using ribose oxidation sequencing (RibOxi-seq) by Zhu, Yinzhou, Pirnie, Stephan P, Carmichael, Gordon G

“…Ribose methylation (2'- -methylation, 2'- Me) occurs at high frequencies in rRNAs and other small RNAs and is carried out using a shared mechanism across…”
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H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase by Zhou, Jichun, Yang, Lihua, Zhong, Tianyu, Mueller, Martin, Men, Yi, Zhang, Na, Xie, Juanke, Giang, Karolyn, Chung, Hunter, Sun, Xueguang, Lu, Lingeng, Carmichael, Gordon G, Taylor, Hugh S, Huang, Yingqun

“…DNA methylation is essential for mammalian development and physiology. Here we report that the developmentally regulated H19 lncRNA binds to and inhibits…”
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Genomewide characterization of non-polyadenylated RNAs by Yang, Li, Duff, Michael O, Graveley, Brenton R, Carmichael, Gordon G, Chen, Ling-Ling

“…RNAs can be physically classified into poly(A)+ or poly(A)- transcripts according to the presence or absence of a poly(A) tail at their 3' ends. Current deep…”
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