Search Results - "Carmena, J"

Anticancer Activity of Dendriplexes against Advanced Prostate Cancer from Protumoral Peptides and Cationic Carbosilane Dendrimers by Sánchez-Milla, María, Muñoz-Moreno, Laura, Sánchez-Nieves, Javier, Malý, Marek, Gómez, Rafael, Carmena, María J, de la Mata, F. Javier

“…The interaction of neuropeptides, vasoactive intestinal peptide (VIP), or growth hormone-releasing hormone (GHRH), with a cationic carbosilane dendrimer forms…”
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Growth hormone-releasing hormone (GHRH) promotes metastatic phenotypes through EGFR/HER2 transactivation in prostate cancer cells by Muñoz-Moreno, Laura, Bajo, Ana M., Prieto, Juan C., Carmena, María J.

“…The involvement of growth hormone-releasing hormone (GHRH) in several relevant processes that contribute to prostate cancer progression was analyzed. Firstly,…”
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Stimulation of neuroendocrine differentiation in prostate cancer cells by GHRH and its blockade by GHRH antagonists by Muñoz-Moreno, Laura, Carmena, María J., Schally, Andrew V., Prieto, Juan C., Bajo, Ana M.

“…Summary Prostate cancer is the second leading cause of cancer-related deaths among men in developed countries. Neuroendocrine prostate cancer, in particular,…”
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A silicon carbide array for electrocorticography and peripheral nerve recording by Diaz-Botia, C A, Luna, L E, Neely, R M, Chamanzar, M, Carraro, C, Carmena, J M, Sabes, P N, Maboudian, R, Maharbiz, M M

“…Current neural probes have a limited device lifetime of a few years. Their common failure mode is the degradation of insulating films and/or the delamination…”
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Nuclear localization of vasoactive intestinal peptide (VIP) receptors in human breast cancer by Valdehita, Ana, Bajo, Ana M., Fernández-Martínez, Ana B., Arenas, M. Isabel, Vacas, Eva, Valenzuela, Pedro, Ruíz-Villaespesa, Antonio, Prieto, Juan C., Carmena, María J.

“…▶ Endocytosis and nuclear translocation of peripheral GPCRs. ▶ VPAC 1 receptor is localized in cell nuclear fraction in human breast. ▶ VPAC 1 receptor is…”
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VIP induces NF-κB1-nuclear localisation through different signalling pathways in human tumour and non-tumour prostate cells by Fernández-Martínez, Ana B., Carmena, María J., Bajo, Ana M., Vacas, Eva, Sánchez-Chapado, Manuel, Prieto, Juan C.

“…The nuclear factor κB (NF-κB) is a powerful activator of angiogenesis, invasion and metastasis. Transactivation and nuclear localisation of NF-κB is an index…”
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Vasoactive intestinal peptide (VIP) induces transactivation of EGFR and HER2 in human breast cancer cells by Valdehita, Ana, Bajo, Ana M., Schally, Andrew V., Varga, Jozsef L., Carmena, María J., Prieto, Juan C.

“…We analyzed the cross-talk between receptors for vasoactive intestinal peptide (VIP) and the human epidermal growth factor family of tyrosine kinase receptors…”
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Growth hormone-releasing hormone induced transactivation of epidermal growth factor receptor in human triple-negative breast cancer cells by Vacas, Eva, Muñoz-Moreno, Laura, Valenzuela, Pedro L., Prieto, Juan C., Schally, Andrew V., Carmena, María J., Bajo, Ana M.

“…•GHRH induces transactivation of EGFR by two different molecular mechanisms.•GHRH stimulates a ligand-independent activation of EGFR involving PKA and…”
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Vasoactive intestinal peptide induces oxidative stress and suppresses metastatic potential in human clear cell renal cell carcinoma by Vacas, Eva, Bajo, Ana M., Schally, Andrew V., Sánchez-Chapado, Manuel, Prieto, Juan C., Carmena, María J.

“…► Vasoactive intestinal peptide (VIP) increases adhesion of renal carcinoma cells. ► VIP decreases migration and extracellular-matrix degradation in tumor…”
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RNA interference-directed silencing of VPAC₁ receptor inhibits VIP effects on both EGFR and HER2 transactivation and VEGF secretion in human breast cancer cells by Valdehita, Ana, Carmena, María J, Bajo, Ana M, Prieto, Juan C

“…We used small-interference RNA (siRNA) to explore the mechanisms of some vasoactive intestinal peptide (VIP) actions on human breast cancer cells. Transfection…”
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Pathway towards an ideal and sustainable framework agreement for the public procurement of vaccines in Spain: a multi-criteria decision analysis by Zozaya González, N., Alcalá Revilla, B., Arrazola Martínez, P., Chávarri Bravo, J. R., Cuesta Esteve, I., García Rojas, A. J., Martinón-Torres, F., Redondo Margüello, E., Rivero Cuadrado, A., Tamames Gómez, S., Villaseca Carmena, J., Hidalgo-Vega, A.

“…Objective: To advance the development of an ideal and sustainable framework agreement for the public procurement of vaccines in Spain, and to agree on the…”
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Inhibitory effects of antagonists of growth hormone‐releasing hormone on growth and invasiveness of PC3 human prostate cancer by Muñoz‐Moreno, Laura, Arenas, M. Isabel, Schally, Andrew V., Fernández‐Martínez, Ana B., Zarka, Elías, González‐Santander, Marta, Carmena, María J., Vacas, Eva, Prieto, Juan C., Bajo, Ana M.

“…New approaches are needed to the therapy of advanced prostate cancer. This study determined the effect of growth hormone‐releasing hormone (GHRH) antagonists,…”
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Vasoactive intestinal peptide (VIP) inhibits human renal cell carcinoma proliferation by Vacas, Eva, Fernández-Martínez, Ana B., Bajo, Ana M., Sánchez-Chapado, Manuel, Schally, Andrew V., Prieto, Juan C., Carmena, María J.

“…Clear renal cell carcinoma (cRCC) is an aggressive and fatal neoplasm. The present work was undertaken to investigate the antiproliferative potential of…”
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Regulation of HER expression and transactivation in human prostate cancer cells by a targeted cytotoxic bombesin analog (AN‐215) and a bombesin antagonist (RC‐3095) by Sotomayor, Sandra, Muñoz‐Moreno, Laura, Carmena, María J., Schally, Andrew V., Sánchez‐Chapado, Manuel, Prieto, Juan C., Bajo, Ana M.

“…Bombesin (BN) and gastrin‐releasing peptide (GRP) have been shown to stimulate the growth of human prostate cancer in vivo and in vitro by mechanisms initiated…”
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Antioxidant activity of vasoactive intestinal peptide in HK2 human renal cells by Vacas, Eva, Bajo, Ana M., Schally, Andrew V., Sánchez-Chapado, Manuel, Prieto, Juan C., Carmena, María J.

“…► VIP decreases ROS levels reached by H2O2-induced oxidative stress. ► VIP increases Bcl-2 and decreases Bax in H2O2-injured HK2 human renal cells. ► The…”
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Anti-proliferative and pro-apoptotic effects of GHRH antagonists in prostate cancer by Muñoz-Moreno, Laura, Arenas, Maria Isabel, Carmena, María J, Schally, Andrew V, Sánchez-Chapado, Manuel, Prieto, Juan C, Bajo, Ana M

“…Growth hormone-releasing hormone (GHRH) and its receptors have been implicated in the progression of various tumors. In vitro and in vivo studies have…”
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Signalling pathways involved in antitumoral effects of VIP in human renal cell carcinoma A498 cells: VIP induction of p53 expression by Vacas, Eva, Muñoz-Moreno, Laura, Fernández-Martínez, Ana B., Bajo, Ana M., Sánchez-Chapado, Manuel, Prieto, Juan C., Carmena, María J.

“…•VIP increases cell adhesion and ROS production in A498 cells.•VIP decreases VEGF165 secretion in A498 renal cancer cells.•VIP induces p53 expression (at mRNA…”
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Vasoactive intestinal peptide (VIP) induces malignant transformation of the human prostate epithelial cell line RWPE-1 by Fernández-Martínez, Ana B, Bajo, Ana M, Isabel Arenas, M, Sánchez-Chapado, Manuel, Prieto, Juan C, Carmena, María J

“…Abstract The carcinogenic potential of vasoactive intestinal peptide (VIP) was analyzed in non-tumor human prostate epithelial cells (RWPE-1) and in vivo…”
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Antitumoral effects of vasoactive intestinal peptide in human renal cell carcinoma xenografts in athymic nude mice by Vacas, Eva, Arenas, M. Isabel, Muñoz-Moreno, Laura, Bajo, Ana M, Sánchez-Chapado, Manuel, Prieto, Juan C, Carmena, María J

“…Highlights • VIP exerted antitumoral effects in renal cell carcinoma xenografts. • VIP upregulated p53 and decreased nuclear β-catenin translocation. • VIP…”
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Vasoactive intestinal peptide behaves as a pro-metastatic factor in human prostate cancer cells by Fernández-Martínez, Ana B., Bajo, Ana M., Sánchez-Chapado, Manuel, Prieto, Juan C., Carmena, María J.

“…BACKGROUND There is little known on the involvement of vasoactive intestinal peptide (VIP) in the metastatic cascade of human prostate cancer, that is, cell…”
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