Search Results - "Carmeliet, E."

Voltage- and time-dependent block of the delayed K+ current in cardiac myocytes by dofetilide by Carmeliet, E

“…The delayed K+ current (ik) and its change by dofetilide was studied in single myocytes from the guinea pig and rabbit heart using the two-electrode voltage…”
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Editorial commentary: This sodium current may be late, but it is important by Giles, Wayne R., PhD, Carmeliet, Edward E., MD, PhD

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Mechanisms and control of repolarization by Carmeliet, E

“…This paper describes and discusses interventions that may lead to prolongation of the action potential. Special emphasis is given to regulation by drugs. The…”
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Use-Dependent Block and Use-Dependent Unblock of the Delayed Rectifier K+ Current by Almokalant in Rabbit Ventricular Myocytes by Carmeliet, Edward

“…A voltage-clamp analysis of the effect of almokalant on the delayed rectifier K current (Ik) was made in rabbit ventricular myocytes. The two-suction pipette…”
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Reduction of Ischemic K+ Loss and Arrhythmias in Rat Hearts: Effect of Glibenclamide, a Sulfonylurea by Kantor, Paul F, Coetzee, William A, Carmeliet, Edward E, Dennis, Steven C, Opie, Lionel H

“…Glibenclamide, one of the antidiabetic sulfonylureas, is known to block ATP-dependent K channels. We used this drug to determine to what extent K loss from…”
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Electrophysiologic and voltage clamp analysis of the effects of sotalol on isolated cardiac muscle and Purkinje fibers by Carmeliet, E

“…The effect of dl-, d- and I-sotalol on electrophysiologic characteristics of guinea-pig papillary muscles, sheep and rabbit Purkinje fibers was studied…”
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T-type Ca2+ current as a trigger for Ca2+ release from the sarcoplasmic reticulum in guinea-pig ventricular myocytes by Sipido, Karin R., Carmeliet, Edward, Werf, F.

“…We have investigated whether Ca 2+ entry through T-type Ca 2+ channels participates in triggering Ca 2+ release from the sarcoplasmic reticulum (SR) in single…”
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Slow inactivation of the sodium current in rabbit cardiac Purkinje fibres by CARMELIET, E

“…An analysis of the slowly inactivating Na current in rabbit cardiac Purkinje fibres was made, using the two-microelectrode voltage clamp technique. The…”
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[Ca2+]i transients and [Ca2+]i-dependent chloride current in single Purkinje cells from rabbit heart by Sipido, K R, Callewaert, G, Carmeliet, E

“…1. Single Purkinje cells, enzymatically isolated from rabbit ventricle, were studied under whole-cell voltage clamp and internally perfused with the…”
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K+ channels and control of ventricular repolarization in the heart by Carmeliet, E

“…K+ channels form a large family, in which voltage-operated and ligand-operated channels can be distinguished. Under physiological conditions, four K+ currents…”
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The effect of external pH on the delayed rectifying K+ current in cardiac ventricular myocytes by Vereecke, J, Carmeliet, E

“…The effects of extracellular pH (pHe) on the delayed rectifying K+ current iKr in rabbit ventricular myocytes were studied using the whole-cell-clamp…”
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Na+ current and Ca2+ release from the sarcoplasmic reticulum during action potentials in guinea-pig ventricular myocytes by Sipido, K R, Carmeliet, E, Pappano, A

“…1. Ca2+ release from the sarcoplasmic reticulum (SR) was examined in enzymatically isolated single guinea-pig ventricular myocytes by monitoring [Ca2+]i with…”
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Stereoselective effects of the enantiomers of bupivacaine on the electrophysiological properties of the guinea‐pig papillary muscle by Vanhoutte, Filip, Vereecke, Johan, Verbeke, Norbert, Carmeliet, Edward

“…1 Direct myocardial effects of the S(−)‐ and R(+)‐enantiomers of bupivacaine were compared in the guinea‐pig isolated papillary muscle by recording…”
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Voltage-dependent block by tetrodotoxin of the sodium channel in rabbit cardiac Purkinje fibers by Carmeliet, E.

“…The two-microelectrode, voltage-clamp technique was applied to rabbit cardiac Purkinje fibers to study the interaction of tetrodotoxin (TTX) with the slowly…”
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Mode of regulation by G protein of the ATP-sensitive K+ channel in guinea-pig ventricular cell membrane by Ito, H, Vereecke, J, Carmeliet, E

“…1. The effect of G protein activation on the ATP-sensitive K+ (K+ATP) channel was examined in inside-out patches from guinea-pig ventricular myocytes. At low…”
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Cardiac Ionic Currents and Acute Ischemia: From Channels to Arrhythmias by Carmeliet, Edward

“…Centre for Experimental Surgery and Anesthesiology, University of Leuven, Leuven, Belgium Carmeliet, Edward Cardiac Ionic Currents and Acute Ischemia: From…”
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Delayed K+ current and external K+ in single cardiac Purkinje cells by Scamps, F, Carmeliet, E

“…The effect of external K+ on the delayed K+ current was investigated in rabbit single Purkinje cells. Whole cell voltage clamp and intracellular dialysis were…”
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Ion channel agonists: expectations for therapy by Carmeliet, E

“…Some animal or plant toxins and man-made drugs exert agonist activity on Na+, Ca2+ and K+ channels. The increase in current through these channels is…”
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Two components of [Ca2+]i-activated Cl- current during large [Ca2+]i transients in single rabbit heart Purkinje cells by Papp, Z, Sipido, K R, Callewaert, G, Carmeliet, E

“…1. Single Purkinje cells, enzymatically isolated from rabbit ventricle, were studied under whole-cell voltage clamp conditions and internally perfused with the…”
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The effect of external pH on the delayed rectifying K+ current in cardiac ventricular myocytes by Vereecke, J., Carmeliet, E.

“…The effects of extracellular pH (pH^sub e^) on the delayed rectifying K^sup +^ current i ^sub Kr^ in rabbit ventricular myocytes were studied using the…”
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