Search Results - "Carlsson, Björn"
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Life Expectancy after Bariatric Surgery in the Swedish Obese Subjects Study
Published in The New England journal of medicine (15-10-2020)“…This study compared long-term mortality and life expectancy among patients who underwent bariatric surgery or received usual obesity care in the Swedish Obese…”
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Bariatric Surgery and Prevention of Type 2 Diabetes in Swedish Obese Subjects
Published in The New England journal of medicine (23-08-2012)“…In this report from the Swedish Obese Subjects study, the rate of incident type 2 diabetes in usual-care and bariatric-surgery groups was 28.4 and 6.8 cases…”
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Short-term effects of obesity surgery versus low-energy diet on body composition and tissue-specific glucose uptake: a randomised clinical study using whole-body integrated 18F-FDG-PET/MRI
Published in Diabetologia (01-07-2024)“…Aims/hypothesis Obesity surgery (OS) and diet-induced weight loss rapidly improve insulin resistance. We aim to investigate the impact of either Roux-en-Y…”
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4
Bariatric Surgery and Long-term Cardiovascular Events
Published in JAMA : the journal of the American Medical Association (04-01-2012)“…CONTEXT Obesity is a risk factor for cardiovascular events. Weight loss might protect against cardiovascular events, but solid evidence is lacking. OBJECTIVE…”
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Simultaneous Measurement of 11 Antibiotics for Use in the Intensive Care Unit by Ultra-High Performance Liquid Chromatography–Tandem Mass Spectrometry
Published in Therapeutic drug monitoring (01-04-2022)“…Recent studies indicate that a high proportion of patients in the intensive care unit fail to attain adequate antibiotic levels. Thus, there is a need to…”
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Effects of Bariatric Surgery on Mortality in Swedish Obese Subjects
Published in The New England journal of medicine (23-08-2007)“…The prospective, controlled Swedish Obese Subjects study enrolled 4047 subjects who either underwent bariatric surgery or received conventional treatment. The…”
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Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice
Published in Molecular metabolism (Germany) (01-04-2019)“…Nonalcoholic fatty liver disease (NAFLD) is becoming a leading cause of advanced chronic liver disease. The progression of NAFLD, including nonalcoholic…”
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An oral antisense oligonucleotide for PCSK9 inhibition
Published in Science translational medicine (12-05-2021)“…Inhibitors of proprotein convertase subtilisin/kexin type 9 (PCSK9) reduce low-density lipoprotein (LDL) cholesterol and are used for treatment of…”
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Effect of Tenapanor on Interdialytic Weight Gain in Patients on Hemodialysis
Published in Clinical journal of the American Society of Nephrology (07-09-2016)“…Interdialytic weight gain in patients on hemodialysis is associated with adverse cardiovascular outcomes and increased mortality. The degree of interdialytic…”
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Pharmacokinetics of Oral Levonorgestrel in Women After Roux-en-Y Gastric Bypass Surgery and in BMI-Matched Controls
Published in Obesity surgery (01-06-2020)“…Background Women are advised to primarily use non-oral contraceptive alternatives after Roux-en-Y gastric bypass since it is not known if the surgery affects…”
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11
Separation of human adipocytes by size: hypertrophic fat cells display distinct gene expression
Published in The FASEB journal (01-07-2006)“…Enlarged adipocytes are associated with insulin resistance and are an independent predictor of type 2 diabetes. To understand the molecular link between these…”
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Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial
Published in The lancet oncology (01-07-2009)“…Summary Background Obesity is a risk factor for cancer. Intentional weight loss in the obese might protect against malignancy, but evidence is limited. To our…”
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Relations of Adipose Tissue CIDEA Gene Expression to Basal Metabolic Rate, Energy Restriction, and Obesity: Population-Based and Dietary Intervention Studies
Published in The journal of clinical endocrinology and metabolism (01-12-2007)“…Context: Cell death-inducing DNA fragmentation factor-α-like effector A (CIDEA) could be a potential target for the treatment of obesity via the modulation of…”
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rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression
Published in iScience (21-02-2020)“…Long-chain polyunsaturated fatty acids (LC-PUFAs) influence human health in several areas, including cardiovascular disease, diabetes, fatty liver disease, and…”
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Hepatic patatin‐like phospholipase domain‐containing 3 levels are increased in I148M risk allele carriers and correlate with NAFLD in humans
Published in Hepatology communications (01-10-2022)“…In nonalcoholic fatty liver disease (NAFLD) the patatin‐like phospholipase domain‐containing 3 (PNPLA3) rs738409 variant is a contributor. In mice, the Pnpla3…”
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A Microarray Search for Genes Predominantly Expressed in Human Omental Adipocytes: Adipose Tissue as a Major Production Site of Serum Amyloid A
Published in The journal of clinical endocrinology and metabolism (01-04-2005)“…To identify genes predominantly expressed in omental adipocytes, microarray expression profiles from 33 human tissues or cell types were analyzed, using an…”
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Evolution of age-related mutation-driven clonal haematopoiesis over 20 years is associated with metabolic dysfunction in obesity
Published in EBioMedicine (01-06-2023)“…Haematopoietic clones caused by somatic mutations with ≥2% variant allele frequency (VAF) increase with age and are linked to risk of haematological…”
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Intestinal, adipose, and liver inflammation in diet-induced obese mice
Published in Metabolism, clinical and experimental (01-12-2008)“…Abstract Chronic inflammation and increased visceral adipose tissue (VAT) are key elements of the metabolic syndrome. Both are considered to play a pathogenic…”
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Low IGF-I Suppresses VEGF-Survival Signaling in Retinal Endothelial Cells: Direct Correlation with Clinical Retinopathy of Prematurity
Published in Proceedings of the National Academy of Sciences - PNAS (08-05-2001)“…Retinopathy of prematurity is a blinding disease, initiated by lack of retinal vascular growth after premature birth. We show that lack of insulin-like growth…”
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Review article: the emerging role of genetics in precision medicine for patients with non‐alcoholic steatohepatitis
Published in Alimentary pharmacology & therapeutics (01-06-2020)“…Summary Background Non‐alcoholic steatohepatitis (NASH) is a severe form of non‐alcoholic fatty liver disease (NAFLD) characterised by liver fat accumulation,…”
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