Search Results - "Carlson, Rolf I"

Chronic ethanol‐mediated hepatocyte apoptosis links to decreased TET1 and 5‐hydroxymethylcytosine formation by Ji, Chengcheng, Nagaoka, Katsuya, Zou, Jing, Casulli, Sarah, Lu, Shaolei, Cao, Kevin Y., Zhang, Hongyu, Iwagami, Yoshifumi, Carlson, Rolf I., Brooks, Keri, Lawrence, Jonathan, Mueller, William, Wands, Jack R., Huang, Chiung-Kuei

“…ABSTRACT The 5‐hydroxymethylcytosine (5hmc) is a newly identified epigenetic modification thought to be regulated by the TET family of proteins. Little…”
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Aspartate beta-hydroxylase promotes cholangiocarcinoma progression by modulating RB1 phosphorylation by Huang, Chiung-Kuei, Iwagami, Yoshifumi, Zou, Jing, Casulli, Sarah, Lu, Shaolei, Nagaoka, Katsuya, Ji, Chengcheng, Ogawa, Kousuke, Cao, Kevin Y., Gao, Jin-Song, Carlson, Rolf I., Wands, Jack R.

“…Cholangiocarcinoma (CCA) is a highly lethal and aggressive disease. Recently, IDH1/2 mutations have been identified in approximately 20% of CCAs which suggests…”
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Lambda phage-based vaccine induces antitumor immunity in hepatocellular carcinoma by Iwagami, Yoshifumi, Casulli, Sarah, Nagaoka, Katsuya, Kim, Miran, Carlson, Rolf I., Ogawa, Kosuke, Lebowitz, Michael S., Fuller, Steve, Biswas, Biswajit, Stewart, Solomon, Dong, Xiaoqun, Ghanbari, Hossein, Wands, Jack R.

“…Hepatocellular carcinoma (HCC) is a difficult to treat tumor with a poor prognosis. Aspartate β-hydroxylase (ASPH) is a highly conserved enzyme overexpressed…”
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Rat Strain Differences in Susceptibility to Alcohol-Induced Chronic Liver Injury and Hepatic Insulin Resistance by DeNucci, Sarah M., Tong, Ming, Longato, Lisa, Lawton, Margot, Setshedi, Mashiko, Carlson, Rolf I., Wands, Jack R., de la Monte, Suzanne M.

“…The finding of more severe steatohepatitis in alcohol fed Long Evans (LE) compared with Sprague Dawley (SD) and Fisher 344 (FS) rats prompted us to determine…”
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Aspartate β‐hydroxylase modulates cellular senescence through glycogen synthase kinase 3β in hepatocellular carcinoma by Iwagami, Yoshifumi, Huang, Chiung‐Kuei, Olsen, Mark J., Thomas, John‐Michael, Jang, Grace, Kim, Miran, Lin, Qiushi, Carlson, Rolf I., Wagner, Carl E., Dong, Xiaoqun, Wands, Jack R.

“…Aspartate β‐hydroxylase (ASPH) is an enzyme overexpressed in human hepatocellular carcinoma (HCC) tumors that participates in the malignant transformation…”
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Anti-tumor activity of antibody drug conjugate targeting aspartate-β-hydroxylase in pancreatic ductal adenocarcinoma by Nagaoka, Katsuya, Bai, Xuewei, Ogawa, Kosuke, Dong, Xiaoqun, Zhang, Songhua, Zhou, Yanmei, Carlson, Rolf I., Jiang, Zhi-Gang, Fuller, Steve, Lebowitz, Michael S., Ghanbari, Hossein, Wands, Jack R.

“…Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive malignancy with very limited treatment options. Antibody drug conjugates (ADCs) are…”
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Tumor progression-related transmembrane protein aspartate-β-hydroxylase is a target for immunotherapy of hepatocellular carcinoma by Shimoda, Masafumi, Tomimaru, Yoshito, Charpentier, Kevin P, Safran, Howard, Carlson, Rolf I, Wands, Jack

“…Background & Aims Hepatocellular carcinoma (HCC) has a poor survival rate due to recurrent intrahepatic metastases and lack of effective adjuvant therapy…”
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Role of aspartyl-(asparaginyl) β -hydroxylase in placental implantation: relevance to early pregnancy loss by Gundogan, Fusun, MD, Elwood, Gwen, Greco, David, BS, Rubin, Lewis P., MD, Pinar, Halit, MD, Carlson, Rolf I., BS, Wands, Jack R., MD, de la Monte, Suzanne M., MD, MPH

“…Summary Aspartyl-(asparaginyl) β -hydroxylase (AAH) is a type 2 transmembrane protein with catalytic activity that hydroxylates epidermal growth factor–like…”
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LRH1 as a driving factor in pancreatic cancer growth by Lin, Qiushi, Aihara, Arihiro, Chung, Waihong, Li, Yu, Huang, Zheping, Chen, Xuesong, Weng, Shaofan, Carlson, Rolf I, Wands, Jack R, Dong, Xiaoqun

“…Abstract Liver receptor homolog 1 (LRH1), directs the development and differentiation of embryonic pancreas, and is overexpressed in pancreatic cancer (PC). We…”
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LRH1 promotes pancreatic cancer metastasis by Lin, Qiushi, Aihara, Arihiro, Chung, Waihong, Li, Yu, Chen, Xuesong, Huang, Zheping, Weng, Shaofan, Carlson, Rolf I, Nadolny, Christina, Wands, Jack R, Dong, Xiaoqun

“…Abstract The transcriptional factor liver receptor homolog 1 (LRH1) regulates pancreatic development, and may participate in pancreatic oncogenesis through…”
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Human aspartyl (asparaginyl) β-hydroxylase monoclonal antibodies: Potential biomarkers for Pancreatic carcinoma by PALUMBO, Kevin S, WANDS, Jack R, SAFRAN, Howard, KING, Thomas, CARLSON, Rolf I, DE LA MONTE, Suzanne M

“…Pancreatic adenocarcinoma is among the top 10 leading causes of death due to cancer in the United States. The lack of reliable and sensitive biomarkers for…”
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Ethanol inhibition of aspartyl-asparaginyl-β-hydroxylase in fetal alcohol spectrum disorder: Potential link to the impairments in central nervous system neuronal migration by de la Monte, Suzanne M, Tong, Ming, Carlson, Rolf I, Carter, Jade J, Longato, Lisa, Silbermann, Elizabeth, Wands, Jack R

“…Abstract Fetal alcohol spectrum disorder (FASD) is caused by prenatal exposure to alcohol and associated with hypoplasia and impaired neuronal migration in the…”
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Properties of Monoclonal Antibodies Directed against Hepatitis B Virus Polymerase Protein by zu Putlitz, J, Lanford, R E, Carlson, R I, Notvall, L, de la Monte, S M, Wands, J R

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Profiles of Neuronal Thread Protein Expression in Alzheimer's Disease by de la Monte, Suzanne M, Carlson, Rolf I, Brown, Nancy V, Wands, Jack R

“…Neuronal thread proteins (NTPs) comprise a family of molecules expressed in brain and primitive neuroectodermal tumor cell lines. In Alzheimer's disease (AD),…”
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Aspartate [beta]-hydroxylase modulates cellular senescence through glycogen synthase kinase 3[beta] in hepatocellular carcinoma by Iwagami, Yoshifumi, Huang, Chiung-Kuei, Olsen, Mark J, Thomas, John-Michael, Jang, Grace, Kim, Miran, Lin, Qiushi, Carlson, Rolf I, Wagner, Carl E, Dong, Xiaoqun, Wands, Jack R

“…Aspartate [beta]-hydroxylase (ASPH) is an enzyme overexpressed in human hepatocellular carcinoma (HCC) tumors that participates in the malignant transformation…”
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Aspartate β-hydroxylase modulates cellular senescence via glycogen synthase kinase 3β in hepatocellular carcinoma by Iwagami, Yoshifumi, Huang, Chiung-Kuei, Olsen, Mark J., Thomas, John-Michael, Jang, Grace, Kim, Miran, Lin, Qiushi, Carlson, Rolf I., Wagner, Carl E., Dong, Xiaoqun, Wands, Jack R.

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Bio-nanoparticle based therapeutic vaccine induces immunogenic response against triple negative breast cancer by Bai, Xuewei, Zhou, Yanmei, Lin, Qiushi, Huang, Chiung-Kuei, Zhang, Songhua, Carlson, Rolf I, Ghanbari, Hossein, Sun, Bei, Wands, Jack R, Dong, Xiaoqun

“…Triple negative breast cancer (TNBC) is more aggressive and has a poorer prognosis than other sub-types of breast tumors. This study elucidates how aspartate…”
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PROFILES OF NEURONAL THREAD PROTEIN EXPRESSION IN ALZHEIMERʼS DISEASE by de la Monte, Suzanne M, Carlson, Rolf I, Brown, Nancy V, Wands, Jack R

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Impaired Placentation in Fetal Alcohol Syndrome by Gundogan, F, Elwood, G, Longato, L, Tong, M, Feijoo, A, Carlson, R.I, Wands, J.R, de la Monte, S.M

“…Abstract Intrauterine growth restriction (IUGR) is one of the key features of fetal alcohol syndrome (FAS), and IUGR can be mediated by impaired placentation…”
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Ethanol inhibition of aspartyl-asparaginyl-[beta]-hydroxylase in fetal alcohol spectrum disorder: Potential link to the impairments in central nervous system neuronal migration by de la Monte, Suzanne M, Tong, Ming, Carlson, Rolf I, Carter, Jade J, Longato, Lisa, Silbermann, Elizabeth, Wands, Jack R

“…Fetal alcohol spectrum disorder (FASD) is caused by prenatal exposure to alcohol and associated with hypoplasia and impaired neuronal migration in the…”
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