Search Results - "Carlsen, Jan E."

Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock: The SEPSIS-ACT Randomized Clinical Trial by Laterre, Pierre-Francois, Berry, Scott M, Blemings, Allan, Carlsen, Jan E, François, Bruno, Graves, Todd, Jacobsen, Karsten, Lewis, Roger J, Opal, Steven M, Perner, Anders, Pickkers, Peter, Russell, James A, Windeløv, Nis A, Yealy, Donald M, Asfar, Pierre, Bestle, Morten H, Muller, Grégoire, Bruel, Cédric, Brulé, Noëlle, Decruyenaere, Johan, Dive, Alain-Michel, Dugernier, Thierry, Krell, Kenneth, Lefrant, Jean-Yves, Megarbane, Bruno, Mercier, Emmanuelle, Mira, Jean-Paul, Quenot, Jean-Pierre, Rasmussen, Bodil Steen, Thorsen-Meyer, Hans-Christian, Vander Laenen, Margot, Vang, Marianne Lauridsen, Vignon, Philippe, Vinatier, Isabelle, Wichmann, Sine, Wittebole, Xavier, Kjølbye, Anne Louise, Angus, Derek C

“…IMPORTANCE: Norepinephrine, the first-line vasopressor for septic shock, is not always effective and has important catecholaminergic adverse effects…”
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Rationale and Design of an Adaptive Phase 2b/3 Clinical Trial of Selepressin for Adults in Septic Shock. Selepressin Evaluation Programme for Sepsis-induced Shock-Adaptive Clinical Trial by Lewis, Roger J, Angus, Derek C, Laterre, Pierre-François, Kjølbye, Anne Louise, van der Meulen, Egbert, Blemings, Allan, Graves, Todd, Russell, James A, Carlsen, Jan E, Jacobsen, Karsten, Yealy, Donald M, Opal, Steven M, Windeløv, Nis A, François, Bruno, Perner, Anders, Pickkers, Peter, Berry, Scott M

“…Septic shock carries substantial morbidity and mortality. The failure of many promising therapies during late-phase clinical trials prompted calls for…”
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A Clinical Trial of the Angiotensin-Converting–Enzyme Inhibitor Trandolapril in Patients with Left Ventricular Dysfunction after Myocardial Infarction by Køber, Lars, Torp-Pedersen, Christian, Carlsen, Jan E, Bagger, Henning, Eliasen, Per, Lyngborg, Kjeld, Videbæk, Jørgen, Cole, David S, Auclert, Laurent, Pauly, Nancy C, Aliot, Etienne, Persson, Stig, Camm, A. John

“…A series of clinical trials 1 – 7 have examined the effects of angiotensin-converting–enzyme (ACE) inhibitors on survival after acute myocardial infarction…”
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A randomised trial of a pre-synaptic stimulator of DA(2)-dopaminergic and alpha(2)-adrenergic receptors on morbidity and mortality in patients with heart failure by Torp-Pedersen, Christian, Kober, Lars, Carlsen, Jan E., Akkan, Dilek, Bruun, Niels E., Dacoronias, Dimitri, Dickstein, Kenneth, Haghfelt, Torben, Öhlin, Hans, McMurray, John J. V.

“…Background: By pre-synaptic stimulation of DA(2)-dopaminergic and alpha(2)-adrenergic receptors, nolomirole inhibits norepinephrine secretion from sympathetic…”
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A randomised trial of a pre-synaptic stimulator of DA2-dopaminergic and α2-adrenergic receptors on morbidity and mortality in patients with heart failure by Torp-Pedersen, Christian, Køber, Lars, Carlsen, Jan E., Akkan, Dilek, Bruun, Niels E., Dacoronias, Dimitri, Dickstein, Kenneth, Haghfelt, Torben, Öhlin, Hans, McMurray, John JV

“…Background: By pre-synaptic stimulation of DA2-dopaminergic and α2-adrenergic receptors, nolomirole inhibits norepinephrine secretion from sympathetic nerve…”
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Cardiovascular and adrenergic effects of cigarette smoking during immediate non-selective and selective beta adrenoceptor blockade in humans by Trap-Jensen, J, Carlsen, J E, Svendsen, T L, Christensen, N J

“…The cardiovascular and adrenergic responses to cigarette smoking during acute selective and non-selective beta adrenoceptor blockade were studied in seven…”
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Acute hemodynamic effects of pinacidil and hydralazine in essential hypertension by Carlsen, J E, Kardel, T, Lund, J O, McNair, A, Trap-Jensen, J

“…In a double-blind, randomized, crossover study, the effects of intravenous pinacidil, 0.2 mg/kg, were compared with those of hydralazine, 0.3 mg/kg, before and…”
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A randomised trial of a pre‐synaptic stimulator of DA 2 ‐dopaminergic and α 2 ‐adrenergic receptors on morbidity and mortality in patients with heart failure by Torp‐Pedersen, Christian, Køber, Lars, Carlsen, Jan E., Akkan, Dilek, Bruun, Niels E., Dacoronias, Dimitri, Dickstein, Kenneth, Haghfelt, Torben, Öhlin, Hans, McMurray, John JV

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A randomised trial of a pre-synaptic stimulator of DA2-dopaminergic and alpha2-adrenergic receptors on morbidity and mortality in patients with heart failure by Torp-Pedersen, Christian, Køber, Lars, Carlsen, Jan E, Akkan, Dilek, Bruun, Niels E, Dacoronias, Dimitri, Dickstein, Kenneth, Haghfelt, Torben, Ohlin, Hans, McMurray, John J V

“…By pre-synaptic stimulation of DA(2)-dopaminergic and alpha(2)-adrenergic receptors, nolomirole inhibits norepinephrine secretion from sympathetic nerve…”
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Relation between dose of bendrofluazide, antihypertensive effect, and adverse biochemical effects by Carlsen, J E, Køber, L, Torp-Pedersen, C, Johansen, P

“…OBJECTIVE--To determine the relevant dose of bendrofluazide for treating mild to moderate hypertension. DESIGN--Double blind parallel group trial of patients…”
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Consecutive screening and enrollment in clinical trials: The way to representative patient samples? by Bjørn, Mette, Brendstrup, Connie, Karlsen, Sven, Carlsen, Jan E.

“…Trials usually do little or nothing to ensure random samples of patients representative of the disease under investigation. To evaluate the effects of…”
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Consecutive screening and enrollment on clinical trials by Bjørn, Mette, Brendstrup, Connie, Karlsen, Sven, Carlsen, Jan E.

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Blood Pressure Lowering Effect and Adverse Events During Treatment of Arterial Hypertension with Isradipine and Hydrochlorothiazide by Carlsen, Jan E., Køber, Lars

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Pharmacokinetic and Pharmacodynamic Evaluation of Two Different Oral Formulations of Pinacidil, a Potassium Channel Opener by Carlsen, Jan E., Køber, Lars, Rehling, Michael

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A Randomised Comparison of Acebutolol and Metoprolol in 215 Patients With Hypertension: Lack of Importance of Intrinsic Sympathomimetic Activity and Solubility For Adverse Effects by Carlsen, Jan E., Kober, Lars, Heeboll-Nielsen, Niels C.

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Pinacidil: potassium channel openers in the treatment of hypertension, Copenhagen, 10-11 March, 1988 by CARLSEN, Jan E, WESTON, Arthur H, JENSEN, H. Aerenlund

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Comparison of Four Commercial Tc-99m(Sn)DTPA Preparations Used for the Measurement of Glomerular Filtration Rate: Concise Communication by Carlsen, Jan E, Moller, Michael Lehd, Lund, Jens O, Trap-Jensen, Jens

“…To find a commercially available DTPA preparation that could be used for the measurement of glomerular filtration rate (GFR), the plasma clearances of four…”
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Antihypertensive and adverse biochemical effects of bendrofluazide: Authors' reply by Carlsen, Jan E, Køber, Lars, Torp-Pedersen, Christian, Johansen, Peter

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Comparison of Efficacy and Tolerability of Spirapril and Nitrendipine in Arterial Hypertension by Carlsen, Jan E., Galløe, Anders, Køber, Lars, Leikersfeldt, Gerd, Winther, Anders, Lund, Jette, Pétersen, Lone Nørgård, McNair, Allan

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Immediate central and peripheral haemodynamic effects of a new vasodilating agent Pinacidil (P1134) in hypertensive man by Carlsen, J E, Kardel, T, Hilden, T, Tangø, M, Trap-Jensen, J

“…The purpose of this study was to evaluate the immediate central and peripheral haemodynamic effects of a new vasodilating agent P 1134, in hypertensive man…”
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