Search Results - "Carlow, Clotilde"

Development and implementation of a simple and rapid extraction-free saliva SARS-CoV-2 RT-LAMP workflow for workplace surveillance by Li, Zhiru, Bruce, Jacqueline L, Cohen, Barry, Cunningham, Caileigh V, Jack, William E, Kunin, Katell, Langhorst, Bradley W, Miller, Jacob, Moncion, Reynes A, Poole, Catherine B, Premsrirut, Prem K, Ren, Guoping, Roberts, Richard J, Tanner, Nathan A, Zhang, Yinhua, Carlow, Clotilde K S

“…Effective management of the COVID-19 pandemic requires widespread and frequent testing of the population for SARS-CoV-2 infection. Saliva has emerged as an…”
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Colorimetric tests for diagnosis of filarial infection and vector surveillance using non-instrumented nucleic acid loop-mediated isothermal amplification (NINA-LAMP) by Poole, Catherine B, Li, Zhiru, Alhassan, Andy, Guelig, Dylan, Diesburg, Steven, Tanner, Nathan A, Zhang, Yinhua, Evans, Jr, Thomas C, LaBarre, Paul, Wanji, Samuel, Burton, Robert A, Carlow, Clotilde K S

“…Accurate detection of filarial parasites in humans is essential for the implementation and evaluation of mass drug administration programs to control…”
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Characterization of transcription factors that regulate the type IV secretion system and riboflavin biosynthesis in Wolbachia of Brugia malayi by Li, Zhiru, Carlow, Clotilde K S

“…The human filarial parasite Brugia malayi harbors an endosymbiotic bacterium Wolbachia (wBm) that is required for parasite survival. Consequently, targeting…”
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Expanding the MDx toolbox for filarial diagnosis and surveillance by Alhassan, Andy, Li, Zhiru, Poole, Catherine B, Carlow, Clotilde K.S

“…Highlights • Accurate parasite detection is essential for filariasis control. • Current tools are inadequate to detect low parasite numbers in humans and…”
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Extraction-free LAMP assays for generic detection of Old World Orthopoxviruses and specific detection of Mpox virus by Li, Zhiru, Sinha, Amit, Zhang, Yinhua, Tanner, Nathan, Cheng, Hui-Ting, Premsrirut, Prem, Carlow, Clotilde K. S.

“…Mpox is a neglected zoonotic disease endemic in West and Central Africa. The Mpox outbreak with more than 90,000 cases worldwide since 2022 generated great…”
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Identification of putative effectors of the Type IV secretion system from the Wolbachia endosymbiont of Brugia malayi by Carpinone, Emily M, Li, Zhiru, Mills, Michael K, Foltz, Clemence, Brannon, Emma R, Carlow, Clotilde K S, Starai, Vincent J

“…Wolbachia is an unculturable, intracellular bacterium that persists within an extremely broad range of arthropod and parasitic nematode hosts, where it is…”
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A simple isothermal DNA amplification method to screen black flies for Onchocerca volvulus infection by Alhassan, Andy, Makepeace, Benjamin L, LaCourse, Elwyn James, Osei-Atweneboana, Mike Y, Carlow, Clotilde K S

“…Onchocerciasis is a debilitating neglected tropical disease caused by infection with the filarial parasite Onchocerca volvulus. Adult worms live in…”
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Complete Genome Sequence of the Wolbachia wAlbB Endosymbiont of Aedes albopictus by Sinha, Amit, Li, Zhiru, Sun, Luo, Carlow, Clotilde K S

“…Wolbachia, an alpha-proteobacterium closely related to Rickettsia, is a maternally transmitted, intracellular symbiont of arthropods and nematodes. Aedes…”
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Diagnosis of brugian filariasis by loop-mediated isothermal amplification by Poole, Catherine B, Tanner, Nathan A, Zhang, Yinhua, Evans, Jr, Thomas C, Carlow, Clotilde K S

“…In this study we developed and evaluated a Brugia Hha I repeat loop-mediated isothermal amplification (LAMP) assay for the rapid detection of Brugia genomic…”
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Molecular Surveillance Detects High Prevalence of the Neglected Parasite Mansonella ozzardi in the Colombian Amazon by Dahmer, Kendra J, Palma-Cuero, Monica, Ciuoderis, Karl, Patiño, Claudia, Roitman, Sofia, Li, Zhiru, Sinha, Amit, Hite, Jessica L, Cuellar, Olga Bellido, Hernandez-Ortiz, Juan P, Osorio, Jorge E, Christensen, Bruce M, Carlow, Clotilde K S, Zamanian, Mostafa

“…Abstract Background Mansonellosis is an undermapped insect-transmitted disease caused by filarial nematodes that are estimated to infect hundreds of millions…”
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Genome Filtering for New DNA Biomarkers of Loa loa Infection Suitable for Loop-Mediated Isothermal Amplification by Poole, Catherine B, Ettwiller, Laurence, Tanner, Nathan A, Evans, Jr, Thomas C, Wanji, Samuel, Carlow, Clotilde K S

“…Loa loa infections have emerged as a serious public health problem in patients co-infected with Onchocerca volvulus or Wuchereria bancrofti because of severe…”
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Computational prediction of essential genes in an unculturable endosymbiotic bacterium, Wolbachia of Brugia malayi by Holman, Alexander G, Davis, Paul J, Foster, Jeremy M, Carlow, Clotilde K S, Kumar, Sanjay

“…Wolbachia (wBm) is an obligate endosymbiotic bacterium of Brugia malayi, a parasitic filarial nematode of humans and one of the causative agents of lymphatic…”
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Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases by Yu, Hao, Dranchak, Patricia, Li, Zhiru, MacArthur, Ryan, Munson, Matthew S., Mehzabeen, Nurjahan, Baird, Nathan J., Battalie, Kevin P., Ross, David, Lovell, Scott, Carlow, Clotilde K. S., Suga, Hiroaki, Inglese, James

“…Glycolytic interconversion of phosphoglycerate isomers is catalysed in numerous pathogenic microorganisms by a cofactor-independent mutase (iPGM) structurally…”
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Mining predicted essential genes of Brugia malayi for nematode drug targets by Kumar, Sanjay, Chaudhary, Kshitiz, Foster, Jeremy M, Novelli, Jacopo F, Zhang, Yinhua, Wang, Shiliang, Spiro, David, Ghedin, Elodie, Carlow, Clotilde K S

“…We report results from the first genome-wide application of a rational drug target selection methodology to a metazoan pathogen genome, the completed draft…”
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Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs by Farelli, Jeremiah D, Galvin, Brendan D, Li, Zhiru, Liu, Chunliang, Aono, Miyuki, Garland, Megan, Hallett, Olivia E, Causey, Thomas B, Ali-Reynolds, Alana, Saltzberg, Daniel J, Carlow, Clotilde K S, Dunaway-Mariano, Debra, Allen, Karen N

“…Parasitic nematodes are responsible for devastating illnesses that plague many of the world's poorest populations indigenous to the tropical areas of…”
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Interdomain lateral gene transfer of an essential ferrochelatase gene in human parasitic nematodes by Wu, Bo, Novelli, Jacopo, Jiang, Daojun, Dailey, Harry A., Landmann, Frédéric, Ford, Louise, Taylor, Mark J., Carlow, Clotilde K. S., Kumar, Sanjay, Foster, Jeremy M., Slatko, Barton E.

“…Lateral gene transfer events between bacteria and animals highlight an avenue for evolutionary genomic loss/gain of function. Herein, we report functional…”
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Draft Genome of the Filarial Nematode Parasite Brugia malayi by Ghedin, Elodie, Wang, Shiliang, Spiro, David, Caler, Elisabet, Zhao, Qi, Crabtree, Jonathan, Allen, Jonathan E., Delcher, Arthur L., Guiliano, David B., Miranda-Saavedra, Diego, Angiuoli, Samuel V., Creasy, Todd, Amedeo, Paolo, Haas, Brian, El-Sayed, Najib M., Wortman, Jennifer R., Feldblyum, Tamara, Tallon, Luke, Schatz, Michael, Shumway, Martin, Koo, Hean, Salzberg, Steven L., Schobel, Seth, Pertea, Mihaela, Pop, Mihai, White, Owen, Barton, Geoffrey J., Carlow, Clotilde K. S., Crawford, Michael J., Daub, Jennifer, Dimmic, Matthew W., Estes, Chris F., Foster, Jeremy M., Ganatra, Mehul, Gregory, William F., Johnson, Nicholas M., Jin, Jinming, Komuniecki, Richard, Korf, Ian, Kumar, Sanjay, Laney, Sandra, Li, Ben-Wen, Li, Wen, Lindblom, Tim H., Lustigman, Sara, Ma, Dong, Maina, Claude V., Martin, David M. A., McCarter, James P., McReynolds, Larry, Mitreva, Makedonka, Nutman, Thomas B., Parkinson, John, Peregrín-Alvarez, José M., Poole, Catherine, Ren, Qinghu, Saunders, Lori, Sluder, Ann E., Smith, Katherine, Stanke, Mario, Unnasch, Thomas R., Ware, Jenna, Wei, Aguan D., Weil, Gary, Williams, Deryck J., Zhang, Yinhua, Williams, Steven A., Fraser-Liggett, Claire, Slatko, Barton, Blaxter, Mark L., Scott, Alan L.

“…Parasitic nematodes that cause elephantiasis and river blindness threaten hundreds of millions of people in the developing world. We have sequenced the ∼90…”
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Multiple Lineages of Nematode-Wolbachia Symbiosis in Supergroup F and Convergent Loss of Bacterioferritin in Filarial Wolbachia by Sinha, Amit, Li, Zhiru, Poole, Catherine B, Ettwiller, Laurence, Lima, Nathália F, Ferreira, Marcelo U, Fombad, Fanny F, Wanji, Samuel, Carlow, Clotilde K S

“…Abstract The intracellular endosymbiotic proteobacteria Wolbachia have evolved across the phyla nematoda and arthropoda. In Wolbachia phylogeny, supergroup F…”
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A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes by Galvin, Brendan D, Li, Zhiru, Villemaine, Estelle, Poole, Catherine B, Chapman, Melissa S, Pollastri, Michael P, Wyatt, Paul G, Carlow, Clotilde K S

“…Myristoylation is a lipid modification involving the addition of a 14-carbon unsaturated fatty acid, myristic acid, to the N-terminal glycine of a subset of…”
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Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment by Abong, Raphael Awah, Amambo, Glory N, Chounna Ndongmo, Patrick W, Njouendou, Abdel Jelil, Ritter, Manuel, Beng, Amuam Andrew, Esum, Mathias Eyong, Deribe, Kebede, Fru-Cho, Jerome, Fombad, Fanny F, Nji, Theobald Mue, Enyong, Peter Ivo, Poole, Catherine B, Pfarr, Kenneth, Hoerauf, Achim, Carlow, Clotilde K S, Wanji, Samuel

“…Ivermectin is an excellent microfilaricide against Onchocerca volvulus. However, in some regions, long term use of ivermectin has resulted in sub-optimal…”
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