Search Results - "Carlos Carvalho Navegantes, Luiz"
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Comparison between low, moderate, and high intensity aerobic training with equalized loads on biomarkers and performance in rats
Published in Scientific reports (27-10-2022)“…This study investigated the physiological and molecular responses of Wistar Hannover rats, submitted to three 5-week chronic training models, with similar…”
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2
Phosphodiesterase 4 inhibition restrains muscle proteolysis in diabetic rats by activating PKA and EPAC/Akt effectors and inhibiting FoxO factors
Published in Life sciences (1973) (01-08-2021)“…There is growing evidence about the ability of cyclic adenosine monophosphate (cAMP) signaling and nonselective phosphodiesterase (PDE) inhibitors on mitigate…”
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3
Activation of adipose tissue glycerokinase contributes to increased white adipose tissue mass in mice fed a high-fat diet
Published in Endocrine (01-07-2020)“…Purpose Investigate the pathways of glycerol-3-P (G3P) generation for triacylglycerol (TAG) synthesis in retroperitoneal (RWAT) and epididymal (EWAT) white…”
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4
Differential regulation of glyceroneogenesis by glucocorticoids in epididymal and retroperitoneal white adipose tissue from rats
Published in Endocrine (01-08-2017)“…Purpose Investigate the glycerol-3-phosphate generation pathways in epididymal (EPI) and retroperitoneal (RETRO) adipose tissues from dexamethasone-treated…”
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5
Diminazene aceturate attenuates systemic inflammation via microbiota gut-5-HT brain-spleen sympathetic axis in male mice
Published in Brain, behavior, and immunity (01-07-2024)“…•DIZE reduces intestinal inflammation, modulating 5-HT levels.•DIZE modulates the gut microbiota to increase central 5-HT during endotoxemia.•Central 5-HT…”
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6
Central angiotensin-(1–7) attenuates hypoglycemia in sepsis-like conditions via reducing systemic and hepatic inflammation
Published in Cytokine (Philadelphia, Pa.) (01-07-2024)“…•Central administration of Ang-(1–7) attenuates LPS-induced hypoglycemia.•Central Ang-(1–7) attenuates LPS-induced inhibition of the gluconeogenesis…”
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7
Glucocorticoids decrease thermogenic capacity and increase triacylglycerol synthesis by glycerokinase activation in the brown adipose tissue of rats
Published in Lipids (01-11-2022)“…Although it is well established that glucocorticoids inactivate thermogenesis and promote lipid accumulation in interscapular brown adipose tissue (IBAT), the…”
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Involvement of cAMP/EPAC/Akt signaling in the antiproteolytic effects of pentoxifylline on skeletal muscles of diabetic rats
Published in Journal of applied physiology (1985) (01-03-2018)“…Advances in the knowledge of the mechanisms controlling protein breakdown in skeletal muscles have allowed the exploration of new options for treating…”
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9
Decreased rate of protein synthesis, caspase-3 activity, and ubiquitin-proteasome proteolysis in soleus muscles from growing rats fed a low-protein, high-carbohydrate diet
Published in Canadian journal of physiology and pharmacology (01-06-2014)“…The aim of this study was to investigate the changes in the rates of both protein synthesis and breakdown, and the activation of intracellular effectors that…”
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10
Effect of cyclosporine a on glucose interstitial concentration in renal cortex and medulla from rats
Published in American journal of nephrology (01-01-2006)“…To standardize microdialysis in rat kidneys and address cyclosporine A (CsA) effects on renal cortex and medulla interstitial glucose. Munich-Wistar rats were…”
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11
The sympathetic nervous system regulates the three glycerol-3P generation pathways in white adipose tissue of fasted, diabetic and high-protein diet-fed rats
Published in Metabolism, clinical and experimental (01-10-2012)“…Abstract The aim of the present study was to investigate the participation of the sympathetic nervous system (SNS) in the control of glycerol-3-P (G3P)…”
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12
Pentoxifylline inhibits Ca2+-dependent and ATP proteasome-dependent proteolysis in skeletal muscle from acutely diabetic rats
Published in American journal of physiology: endocrinology and metabolism (01-03-2007)“…Previous studies from this laboratory have shown that catecholamines exert an inhibitory effect on muscle protein degradation through a pathway involving the…”
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13
Angiotensin-(1−7) improves tail skin heat loss and increases the survival of rats with polymicrobial sepsis
Published in Peptides (New York, N.Y. : 1980) (01-09-2023)“…Sepsis is a serious syndrome, characterized by the excessive release of inflammatory mediators and thermoregulatory changes, being fever the most common sign…”
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14
Alterations of cAMP-dependent signaling in dystrophic skeletal muscle
Published in Frontiers in physiology (17-10-2013)“…Autonomic regulation processes in striated muscles are largely mediated by cAMP/PKA-signaling. In order to achieve specificity of signaling its…”
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15
Mechanisms Involved in 3′,5′-Cyclic Adenosine Monophosphate-Mediated Inhibition of the Ubiquitin-Proteasome System in Skeletal Muscle
Published in Endocrinology (Philadelphia) (01-12-2009)“…Although it is well known that catecholamines inhibit skeletal muscle protein degradation, the molecular underlying mechanism remains unclear. This study was…”
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16
Denervation increase Akt phosphorylation and reduce glyceroneogenesis in white adipose tissue from diabetic rats
Published in The FASEB journal (01-04-2011)“…It has been known that adipose tissue (WAT) has three sources of glycerol‐3‐phosphate (G3P) generation and these pathways seem to be reciprocally controlled to…”
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17
The central administration of C75, a fatty acid synthase inhibitor, activates sympathetic outflow and thermogenesis in interscapular brown adipose tissue
Published in Pflügers Archiv (01-12-2013)“…The present work investigated the participation of interscapular brown adipose tissue (IBAT), which is an important site for thermogenesis, in the anti-obesity…”
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The inhibition of phosphodiesterase 4 reduces skeletal muscle protein catabolism by suppressing autophagy/lysosomal and proteasomal pathways and atrophy‐specific gene transcription
Published in The FASEB journal (01-04-2010)“…This work investigated the effect of cAMP through PDE4 inhibition, the major PDE expressed in skeletal muscle, in modulating muscle protein degradation. The…”
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19
Adrenergic control of protein metabolism in skeletal muscle
Published in Current opinion in clinical nutrition and metabolic care (01-05-2002)“…This review summarizes evidence indicating that the sympathetic nervous system, through hormonal and neurotransmitter actions, produces anabolic,…”
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