Search Results - "Carlos, Chiattone"
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Simplified Geriatric Assessment in Older Patients With Diffuse Large B-Cell Lymphoma: The Prospective Elderly Project of the Fondazione Italiana Linfomi
Published in Journal of clinical oncology (10-04-2021)“…To prospectively validate the use of a simplified geriatric assessment (sGA) at diagnosis and to integrate it into a prognostic score for older patients with…”
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Ethnic and geographic diversity of chronic lymphocytic leukaemia
Published in Leukemia (01-02-2021)“…East Asians, Asian Indians and Amerindians have a five to ten-fold lower age-adjusted incidence rate (AAIR) of chronic lymphocytic leukaemia (CLL) compared…”
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The outcome of peripheral T-cell lymphoma patients failing first-line therapy: a report from the prospective, International T-Cell Project
Published in Haematologica (Roma) (01-07-2018)“…This analysis explored factors influencing survival of patients with primary refractory and relapsed peripheral T-cell lymphomas enrolled in the prospective…”
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Randomized Phase III Study of Alisertib or Investigator's Choice (Selected Single Agent) in Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma
Published in Journal of clinical oncology (10-03-2019)“…The aim of this open-label, first-in-setting, randomized phase III trial was to evaluate the efficacy of alisertib, an investigational Aurora A kinase…”
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Survival outcomes of patients with extranodal natural-killer T-cell lymphoma: a prospective cohort study from the international T-cell Project
Published in The Lancet. Haematology (01-04-2020)“…Extranodal natural killer (NK) T-cell lymphoma (ENKTL) is a unique clinicopathological entity, typically associated with poor survival outcomes. Most published…”
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High-dose extended-field radiotherapy plus chemotherapy improved survival in extranodal NK/T-cell lymphoma in a real-life setting: results from the multicenter T-Cell Brazil Project
Published in Scientific reports (29-11-2022)“…Extranodal natural-killer/T-cell lymphoma (ENKTL) is a rare and aggressive Epstein-Barr virus related mature T-cell and natural-killer malignancy. Although…”
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Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL
Published in Blood (14-03-2013)“…Thanks to modern treatment with all-trans retinoic acid and chemotherapy, acute promyelocytic leukemia (APL) is now the most curable type of leukemia. However,…”
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Randomized Phase III Trial of Ibrutinib and Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Non-Germinal Center B-Cell Diffuse Large B-Cell Lymphoma
Published in Journal of clinical oncology (20-05-2019)“…Ibrutinib has shown activity in non-germinal center B-cell diffuse large B-cell lymphoma (DLBCL). This double-blind phase III study evaluated ibrutinib and…”
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Clinical and histopathology characteristics of Castleman disease: a multicenter study of 51 Brazilian patients
Published in Annals of hematology (01-05-2023)“…Castleman’s disease (CD) is a rare and heterogeneous lymphoproliferative disorder, with limited available clinical information in Brazil. A retrospective study…”
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Management of Chronic Lymphocytic Leukemia in Less-Resourced Countries
Published in The cancer journal (Sudbury, Mass.) (01-07-2021)“…Despite the practice-changing advances achieved in the prognostic stratification and treatment of chronic lymphocytic leukemia (CLL), a large fraction of the…”
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Application of the Central Nervous System International Prognostic Index (CNS-IPI) score in daily practice: a retrospective analysis apart from the clinical trial at two centers in Brazil
Published in Hematology, Transfusion and Cell Therapy (01-04-2024)“…The diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma (NHL) and, despite all the progress in this field, central nervous…”
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Rho kinase inhibition drives megakaryocyte polyploidization and proplatelet formation through MYC and NFE2 downregulation
Published in British journal of haematology (01-03-2014)“…Summary The processes of megakaryocyte polyploidization and demarcation membrane system (DMS) formation are crucial for platelet production, but the mechanisms…”
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Lower socioeconomic status is independently associated with shorter survival in Hodgkin Lymphoma patients—An analysis from the Brazilian Hodgkin Lymphoma Registry
Published in International journal of cancer (01-03-2018)“…Socioeconomic status (SES) is a well‐known determinant of outcomes in cancer. The purpose of this study was to analyze the impact of the SES on the outcomes of…”
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How to manage lymphoid malignancies during novel 2019 coronavirus (CoVid-19) outbreak: a Brazilian task force recommendation
Published in Hematology, Transfusion and Cell Therapy (01-04-2020)“…The novel Coronavirus (CoVid-19) outbreak is now consider a world pandemic, affecting more than 1,300,000 people worldwide. Cancer patients are in risk for…”
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High ΔNp73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia
Published in Blood (12-11-2015)“…The TP73 gene transcript is alternatively spliced and translated into the transcriptionally active (TAp73) or inactive (ΔNp73) isoforms, with opposite effects…”
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Intravascular lymphoma of the central nervous system: a rare subtype of a common disease
Published in Arquivos de neuro-psiquiatria (01-04-2021)“…A 67-year-old man had a sudden onset of headache and aphasia, evolving to spontaneous improvement. A few months later, he developed dysarthria and left…”
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Internal tandem duplication of the FLT3 gene confers poor overall survival in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukemia study
Published in Annals of hematology (01-12-2014)“…Activating internal tandem duplication (ITD) mutations in the fms - like tyrosine kinase 3 ( FLT3 ) gene ( FLT3 -ITD) are associated with poor outcome in acute…”
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