Search Results - "Carlon‐Andres, Irene"
-
1
Glycolysis downregulation is a hallmark of HIV‐1 latency and sensitizes infected cells to oxidative stress
Published in EMBO molecular medicine (09-08-2021)“…HIV‐1 infects lymphoid and myeloid cells, which can harbor a latent proviral reservoir responsible for maintaining lifelong infection. Glycolytic metabolism…”
Get full text
Journal Article -
2
Orthogonal fluorescent chemogenetic reporters for multicolor imaging
Published in Nature chemical biology (01-01-2021)“…Spectrally separated fluorophores allow the observation of multiple targets simultaneously inside living cells, leading to a deeper understanding of the…”
Get full text
Journal Article -
3
Multicolor lifetime imaging and its application to HIV-1 uptake
Published in Nature communications (17-08-2023)“…Simultaneous imaging of nine fluorescent proteins is demonstrated in a single acquisition using fluorescence lifetime imaging microscopy combined with pulsed…”
Get full text
Journal Article -
4
Quantitative FRET-FLIM-BlaM to Assess the Extent of HIV-1 Fusion in Live Cells
Published in Viruses (12-02-2020)“…The first steps of human immunodeficiency virus (HIV) infection go through the engagement of HIV envelope (Env) with CD4 and coreceptors (CXCR4 or CCR5) to…”
Get full text
Journal Article -
5
Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion
Published in PLoS pathogens (21-02-2020)“…There has been resurgence in determining the role of host metabolism in viral infection yet deciphering how the metabolic state of single cells affects viral…”
Get full text
Journal Article -
6
Correction: Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion
Published in PLoS pathogens (10-05-2021)“…[This corrects the article DOI: 10.1371/journal.ppat.1008359.]…”
Get full text
Journal Article -
7
Structure dynamics of HIV-1 Env trimers on native virions engaged with living T cells
Published in Communications biology (27-10-2021)“…The HIV-1 envelope glycoprotein (Env) mediates viral entry into the host cell. Although the highly dynamic nature of Env intramolecular conformations has been…”
Get full text
Journal Article -
8
Structure and Dynamics of HIV-1 ENV Trimers on Native Virions Engaged in Living T Cells
Published in Biophysical journal (12-02-2021)Get full text
Journal Article -
9
Endogenous Labeling for Light Microscopy during HIV-1 Immune Responses
Published in Trends in immunology (01-12-2020)“…New approaches in single molecule spectroscopy and microscopy are able to resolve the spatial and temporal resolution of T cell receptor signaling in the…”
Get full text
Journal Article -
10
CRM1 Promotes Capsid Disassembly and Nuclear Envelope Translocation of Adenovirus Independently of Its Export Function
Published in Journal of virology (09-02-2022)“…After receptor-mediated endocytosis and endosomal escape, adenoviral capsids can travel via microtubule organizing centers to the nuclear envelope. Upon capsid…”
Get full text
Journal Article -
11
Early Steps of Individual Multireceptor Viral Interactions Dissected by High-Density, Multicolor Quantum Dot Mapping in Living Cells
Published in ACS nano (22-10-2024)“…Viral capture and entry to target cells are the first crucial steps that ultimately lead to viral infection. Understanding these events is essential toward the…”
Get full text
Journal Article -
12
In Vivo Labelling of Adenovirus DNA Identifies Chromatin Anchoring and Biphasic Genome Replication
Published in Journal of virology (15-09-2018)“…Adenoviruses are DNA viruses with a lytic infection cycle. Following the fate of incoming as well as recently replicated genomes during infections is a…”
Get full text
Journal Article -
13
Nup358 and Transportin 1 Cooperate in Adenoviral Genome Import
Published in Journal of virology (04-05-2020)“…Nuclear import of viral genomes is an important step during the life cycle of adenoviruses (AdV), requiring soluble cellular factors as well as proteins of the…”
Get full text
Journal Article -
14
Orthogonal fluorescent chemogenetic reporters for multicolor imaging
Published in Nature chemical biology (01-01-2021)Get full text
Journal Article