Search Results - "Carlo M. Croce"

MicroRNA: trends in clinical trials of cancer diagnosis and therapy strategies by Kim, Taewan, Croce, Carlo M.

“…As a type of short noncoding RNAs, microRNA (miRNA) undoubtedly plays a crucial role in cancer development. Since the discovery of the identity and clinical…”
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MicroRNAs in cancer by Di Leva, Gianpiero, Garofalo, Michela, Croce, Carlo M

“…MicroRNAs (miRNAs) are small noncoding RNAs that typically inhibit the translation and stability of messenger RNAs (mRNAs), controlling genes involved in…”
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The role of MicroRNAs in human cancer by Peng, Yong, Croce, Carlo M

“…MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of gene expression. Compelling evidences have demonstrated that miRNA…”
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MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review by Iorio, Marilena V., Croce, Carlo M.

“…Early studies have shown how aberrantly expressed microRNAs are a hallmark of several diseases like cancer. MicroRNA expression profiling was shown to be…”
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MicroRNAs in Cancer: Small Molecules With a Huge Impact by IORIO, Marilena V, CROCE, Carlo M

“…Every cellular process is likely to be regulated by microRNAs, and an aberrant microRNA expression signature is a hallmark of several diseases, including…”
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Finally, An Apoptosis-Targeting Therapeutic for Cancer by Croce, Carlo M, Reed, John C

“…Resistance to cell death represents one of the hallmarks of cancer. Various genetic and epigenetic changes in malignant cells afford cytoprotection in the face…”
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Targeting microRNAs in cancer: rationale, strategies and challenges by Garzon, Ramiro, Croce, Carlo M, Marcucci, Guido

“…Key Points The rationale for using microRNAs (miRNAs) as anticancer drugs is based on two major findings: miRNA expression is deregulated in cancer compared…”
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Role of microRNAs in maintaining cancer stem cells by Garofalo, Michela, Croce, Carlo M.

“…Increasing evidence sustains that the establishment and maintenance of many, if not all, human cancers are due to cancer stem cells (CSCs), tumor cells with…”
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MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review by Iorio, Marilena V, Croce, Carlo M

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microRNAs: Master regulators as potential therapeutics in cancer by Garofalo, Michela, Croce, Carlo M

“…It has been demonstrated that all the known processes involved in cancer, including apoptosis, proliferation, survival, and metastasis, are regulated by small…”
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Prognostic microRNA/mRNA signature from the integrated analysis of patients with invasive breast cancer by Volinia, Stefano, Croce, Carlo M.

“…The optimal management of breast cancer (BC) presents challenges due to the heterogeneous molecular classification of the disease. We performed survival…”
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Long noncoding RNAs: Undeciphered cellular codes encrypting keys of colorectal cancer pathogenesis by Kim, Taewan, Croce, Carlo M.

“…Long noncoding RNAs are non-protein coding transcripts longer than 200 nucleotides in length. By the advance in genetic and bioinformatic technologies, the new…”
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MicroRNAs in Cancer by Garzon, Ramiro, Calin, George A, Croce, Carlo M

“…MicroRNAs (miRNAs) are small, noncoding RNAs with important functions in development, cell differentiation, and regulation of cell cycle and apoptosis. MiRNA…”
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Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression by Pi, Fengmei, Binzel, Daniel W., Lee, Tae Jin, Li, Zhefeng, Sun, Meiyan, Rychahou, Piotr, Li, Hui, Haque, Farzin, Wang, Shaoying, Croce, Carlo M., Guo, Bin, Evers, B. Mark, Guo, Peixuan

“…Nanotechnology offers many benefits, and here we report an advantage of applying RNA nanotechnology for directional control. The orientation of arrow-shaped…”
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MicroRNAs as therapeutic targets in chemoresistance by Garofalo, Michela, Croce, Carlo M

“…Abstract Despite substantial progress in understanding the cancer signaling network, effective therapies remain scarce due to insufficient disruption of…”
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Breast cancer signatures for invasiveness and prognosis defined by deep sequencing of microRNA by Volinia, Stefano, Galasso, Marco, Sana, Maria Elena, Wise, Timothy F, Palatini, Jeff, Huebner, Kay, Croce, Carlo M

“…The transition from ductal carcinoma in situ to invasive ductal carcinoma is a key event in breast cancer progression that is still not well understood. To…”
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MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response by Fabbri, Muller, Paone, Alessio, Calore, Federica, Galli, Roberta, Gaudio, Eugenio, Santhanam, Ramasamy, Lovat, Francesca, Fadda, Paolo, Mao, Charlene, Nuovo, Gerard J, Zanesi, Nicola, Crawford, Melissa, Ozer, Gulcin H, Wernicke, Dorothee, Alder, Hansjuerg, Caligiuri, Michael A, Nana-Sinkam, Patrick, Perrotti, Danilo, Croce, Carlo M

“…MicroRNAs (miRNAs) are small noncoding RNAs, 19–24 nucleotides in length, that regulate gene expression and are expressed aberrantly in most types of cancer…”
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MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer by Boeri, Mattia, Verri, Carla, Conte, Davide, Roz, Luca, Modena, Piergiorgio, Facchinetti, Federica, Calabrò, Elisa, Croce, Carlo M, Pastorino, Ugo, Sozzi, Gabriella

“…The efficacy of computed tomography (CT) screening for early lung cancer detection in heavy smokers is currently being tested by a number of randomized trials…”
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Dysregulation of a family of short noncoding RNAs, tsRNAs, in human cancer by Pekarsky, Yuri, Balatti, Veronica, Palamarchuk, Alexey, Rizzotto, Lara, Veneziano, Dario, Nigita, Giovanni, Rassenti, Laura Z., Pass, Harvey I., Kipps, Thomas J., Liu, Chang-gong, Croce, Carlo M.

“…Chronic lymphocytic leukemia (CLL) is the most common human leukemia, and transgenic mouse studies indicate that activation of the T-cell leukemia/lymphoma 1…”
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Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis by Ueda, Tetsuya, MD, Volinia, Stefano, PhD, Okumura, Hiroshi, MD, Shimizu, Masayoshi, BS, Taccioli, Cristian, PhD, Rossi, Simona, PhD, Alder, Hansjuerg, PhD, Liu, Chang-gong, Prof, Oue, Naohide, MD, Yasui, Wataru, Prof, Yoshida, Kazuhiro, Prof, Sasaki, Hiroki, PhD, Nomura, Sachiyo, MD, Seto, Yasuyuki, Prof, Kaminishi, Michio, Prof, Calin, George A, MD, Croce, Carlo M, Prof

“…Summary Background Analyses of microRNA expression profiles have shown that many microRNAs are expressed aberrantly and correlate with tumorigenesis,…”
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