Search Results - "Carlo, Anne Sophie"

Apolipoprotein E4 disrupts the neuroprotective action of sortilin in neuronal lipid metabolism and endocannabinoid signaling by Asaro, Antonino, Carlo‐Spiewok, Anne‐Sophie, Malik, Anna R., Rothe, Michael, Schipke, Carola G., Peters, Oliver, Heeren, Joerg, Willnow, Thomas E.

“…Introduction Apolipoprotein E (apoE) is a carrier for brain lipids and the most important genetic risk factor for Alzheimer's disease (AD). ApoE binds the…”
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Sorting receptor sortilin—a culprit in cardiovascular and neurological diseases by Carlo, Anne-Sophie, Nykjaer, Anders, Willnow, Thomas E.

“…Sortilin is a sorting receptor that directs target proteins, such as growth factors, signaling receptors, and enzymes, to their destined location in secretory…”
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Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases by Langenfurth, Anika, Rinnenthal, Jan Leo, Vinnakota, Katyayni, Prinz, Vincent, Carlo, Anne-Sophie, Stadelmann, Christine, Siffrin, Volker, Peaschke, Susann, Endres, Matthias, Heppner, Frank, Glass, Rainer, Wolf, Susanne A., Kettenmann, Helmut

“…We previously reported that glioma cells induce the expression of membrane‐type 1 metalloproteinase (MT1‐MMP or MMP‐14) in tumor‐associated…”
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SORLA-Dependent and -Independent Functions for PACS1 in Control of Amyloidogenic Processes by Burgert, Tilman, Schmidt, Vanessa, Caglayan, Safak, Lin, Fuyu, Füchtbauer, Annette, Füchtbauer, Ernst-Martin, Nykjaer, Anders, Carlo, Anne-Sophie, Willnow, Thomas E.

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Sortilin-related Receptor with A-type Repeats (SORLA) Affects the Amyloid Precursor Protein-dependent Stimulation of ERK Signaling and Adult Neurogenesis by Rohe, Michael, Carlo, Anne-Sophie, Breyhan, Henning, Sporbert, Anje, Militz, Daniel, Schmidt, Vanessa, Wozny, Christian, Harmeier, Anja, Erdmann, Bettina, Bales, Kelly R., Wolf, Susanne, Kempermann, Gerd, Paul, Steven M., Schmitz, Dietmar, Bayer, Thomas A., Willnow, Thomas E., Andersen, Olav M.

“…Sortilin-related receptor with A-type repeats (SORLA) is a sorting receptor that impairs processing of amyloid precursor protein (APP) to soluble (s) APP and…”
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SORLA/SORL1 Functionally Interacts with SPAK To Control Renal Activation of Na+-K+-Cl− Cotransporter 2 by Reiche, Juliane, Theilig, Franziska, Rafiqi, Fatema H., Carlo, Anne-Sophie, Militz, Daniel, Mutig, Kerim, Todiras, Mihail, Christensen, Erik Ilsø, Ellison, David H., Bader, Michael, Nykjaer, Anders, Bachmann, Sebastian, Alessi, Dario, Willnow, Thomas E.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Apolipoprotein E receptor pathways in Alzheimer disease by Schmidt, Vanessa, Carlo, Anne-Sophie, Willnow, Thomas E.

“…Alzheimer disease (AD) is the most common neurodegenerative disease affecting millions of patients worldwide. According to the amyloid cascade hypothesis, the…”
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SORLA/SORL1, a neuronal sorting receptor implicated in Alzheimer's disease by Willnow, Thomas E, Carlo, Anne-Sophie, Rohe, Michael, Schmidt, Vanessa

“…The proteolytic breakdown of the amyloid precursor protein (APP) to neurotoxic amyloid-beta peptides in the brain has been recognized as a major pathological…”
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Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation by Caglayan, Safak, Takagi-Niidome, Shizuka, Liao, Fan, Carlo, Anne-Sophie, Schmidt, Vanessa, Burgert, Tilman, Kitago, Yu, Füchtbauer, Ernst-Martin, Füchtbauer, Annette, Holtzman, David M, Takagi, Junichi, Willnow, Thomas E

“…SORLA/SORL1 is a unique neuronal sorting receptor for the amyloid precursor protein that has been causally implicated in both sporadic and autosomal dominant…”
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Sortilin, a novel APOE receptor implicated in Alzheimer disease by Carlo, Anne-Sophie

“…In the brain, apolipoprotein E (APOE) delivers cholesterol-rich lipoproteins to neurons to support synaptogenesis and maintenance of synaptic connections…”
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The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain by Carlo, Anne-Sophie, Gustafsen, Camilla, Mastrobuoni, Guido, Nielsen, Morten S, Burgert, Tilman, Hartl, Daniela, Rohe, Michael, Nykjaer, Anders, Herz, Joachim, Heeren, Joerg, Kempa, Stefan, Petersen, Claus Munck, Willnow, Thomas E

“…Apolipoprotein E (APOE) is the major risk factor for sporadic Alzheimer's disease. Among other functions, APOE is proposed to sequester neurotoxic amyloid-β…”
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Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1 by Rathjen, Thomas, Yan, Xin, Kononenko, Natalia L, Ku, Min-Chi, Song, Kun, Ferrarese, Leiron, Tarallo, Valentina, Puchkov, Dmytro, Kochlamazashvili, Gaga, Brachs, Sebastian, Varela, Luis, Szigeti-Buck, Klara, Yi, Chun-Xia, Schriever, Sonja C, Tattikota, Sudhir Gopal, Carlo, Anne Sophie, Moroni, Mirko, Siemens, Jan, Heuser, Arnd, van der Weyden, Louise, Birkenfeld, Andreas L, Niendorf, Thoralf, Poulet, James F A, Horvath, Tamas L, Tschöp, Matthias H, Heinig, Matthias, Trajkovski, Mirko, Haucke, Volker, Poy, Matthew N

“…The precise mechanisms that cause human obesity remain unknown. Here the authors illustrate how increased expression of Cadm1, a mediator of synapse assembly,…”
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SorLA deficiency dissects amyloid pathology from tau and cholinergic neurodegeneration in a mouse model of Alzheimer's disease by Capsoni, Simona, Carlo, Anne-Sophie, Vignone, Domenico, Amato, Gianluca, Criscuolo, Chiara, Willnow, Thomas E, Cattaneo, Antonino

“…Sortilin-related receptor with A-type repeats (SorLA, also known as LR11) has been implicated in Alzheimer's disease (AD). Thus, genetic studies associated…”
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ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling by Asaro, Antonino, Sinha, Rishabhdev, Bakun, Magda, Kalnytska, Oleksandra, Carlo-Spiewok, Anne-Sophie, Rubel, Tymon, Rozeboom, Annemieke, Dadlez, Michal, Kaminska, Bozena, Aronica, Eleonora, Malik, Anna R, Willnow, Thomas E

“…Sortilin is a neuronal receptor for apolipoprotein E (apoE). Sortilin-dependent uptake of lipidated apoE promotes conversion of polyunsaturated fatty acids…”
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Early developmental expression of leptin receptor gene and [ 125I]leptin binding in the rat forebrain by Carlo, Anne-Sophie, Meyerhof, Wolfgang, Williams, Lynda M.

“…Leptin, via leptin receptors (Ob-R), regulates appetite and energy balance. Of the six isoforms of the receptor identified, so far, only the long form (Ob-Rb)…”
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Identification of Alzheimer disease risk genotype that predicts efficiency of SORL1 expression in the brain by Caglayan, Safak, Bauerfeind, Anja, Schmidt, Vanessa, Carlo, Anne-Sophie, Prabakaran, Thaneas, Hübner, Norbert, Willnow, Thomas E

“…To identify SORL1 risk genotypes that determine receptor protein expression in the human brain. DNA, RNA, and proteins were extracted from brain autopsies of…”
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Pro-neurotrophin receptor sortilin in neurodegenerative processes and Alzheimer's disease by Carlo, Anne-Sophie, Willnow, Thomas, Petersen, Claus Munck, Gustafsen, Camilla

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P1‐004: Pro‐neurotrophin receptor sortilin in neurodegenerative processes and Alzheimer's disease by Carlo, Anne‐Sophie, Willnow, Thomas, Petersen, Claus Munck, Gustafsen, Camilla

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The pro-neurotrophin receptor sortilin is a major neuronal APOE receptor for catabolism of amyloid-β peptide in the brain by Carlo, Anne-Sophie, Gustafsen, Camilla, Mastrobuoni, Guido, Nielsen, Morten, Kempa, Stefan, Petersen, Claus Munck, Willnow, Thomas

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P1‐216: Identification of Alzheimer's Disease Haplotype that Predicts Efficiency of SORL1/SORLA Expression in the Brain by Caglayan, Safak, Schmidt, Vanessa, Carlo, Anne‐Sophie, Bauerfeind, Anja, Huebner, Norbert, Willnow, Thomas

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