Search Results - "Carlino, M"
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Seismic anisotropy to investigate lithospheric-scale tectonic structures and mantle dynamics in southern Italy
Published in Scientific reports (28-11-2023)“…Subduction zones may be characterised by deep-seated tectonic structures whose effects propagate to the upper plate through faulting and magmatism. The overall…”
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Crustal Structure of Etna Volcano (Italy) From P‐Wave Anisotropic Tomography
Published in Geophysical research letters (16-07-2024)“…Several seismic tomographic studies have been carried out to outline the intricate interplay between tectonics and magma uprising at Etna volcano. Most of…”
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Time and space scattered volcanism of Mt. Etna driven by strike-slip tectonics
Published in Scientific reports (20-08-2019)“…High-resolution seismic reflection, magnetic and gravity data, acquired offshore of Etna volcano, provide a new insight to understanding the relationship…”
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Circulating tumour DNA predicts response to anti-PD1 antibodies in metastatic melanoma
Published in Annals of oncology (01-05-2017)“…Programmed death 1 (PD1) inhibitors are now a foundation of medical management of metastatic melanoma. This study sought to determine whether circulating…”
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Anti-PD-1 therapy in patients with advanced melanoma and preexisting autoimmune disorders or major toxicity with ipilimumab
Published in Annals of oncology (01-02-2017)“…Anti-PD-1 antibodies (anti-PD-1) have clinical activity in a number of malignancies. All clinical trials have excluded patients with significant preexisting…”
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A phase I trial of LXS196, a protein kinase C (PKC) inhibitor, for metastatic uveal melanoma
Published in British journal of cancer (06-04-2023)“…Background Up to 50% of patients with uveal melanoma develop metastases (MUM) with a poor prognosis and median overall survival of approximately 1 year…”
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FDG-PET response and outcome from anti-PD-1 therapy in metastatic melanoma
Published in Annals of oncology (01-10-2018)“…Immune checkpoint inhibitor therapy has resulted in impressive and durable clinical activity for many cancers including melanoma; however, there remain few…”
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Management of early melanoma recurrence despite adjuvant anti-PD-1 antibody therapy
Published in Annals of oncology (01-08-2020)“…Anti-programmed cell death protein 1 (PD-1) antibodies (PD1) prolong recurrence-free survival in high-risk resected melanoma; however, approximately 25%–30% of…”
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Correlation of BRAF and NRAS mutation status with outcome, site of distant metastasis and response to chemotherapy in metastatic melanoma
Published in British journal of cancer (15-07-2014)“…Background: The prognostic significance of BRAF and NRAS mutations in metastatic melanoma patients remains uncertain, with several studies reporting…”
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Pre-operative ctDNA predicts survival in high-risk stage III cutaneous melanoma patients
Published in Annals of oncology (01-05-2019)“…The outcomes of patients with stage III cutaneous melanoma who undergo complete surgical resection can be highly variable, and estimation of individual risk of…”
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Delayed immune-related adverse events with anti-PD-1-based immunotherapy in melanoma
Published in Annals of oncology (01-07-2021)“…Immune-related adverse events (irAEs) typically occur within 4 months of starting anti-programmed cell death protein 1 (PD-1)-based therapy [anti-PD-1 ±…”
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Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy
Published in British journal of cancer (10-05-2016)“…Background: Recent phase III clinical trials have established the superiority of the anti-PD-1 antibodies pembrolizumab and nivolumab over the anti-CTLA-4…”
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Efficacy of immune checkpoint inhibitors for the treatment of advanced melanoma in patients with concomitant chronic lymphocytic leukemia
Published in Annals of oncology (01-09-2023)“…Immune checkpoint inhibitors (ICIs) have revolutionized the management of advanced melanoma (AM). However, data on ICI effectiveness have largely been…”
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Activity and safety of radiotherapy with anti-PD-1 drug therapy in patients with metastatic melanoma
Published in Oncoimmunology (01-09-2016)“…The anti-PD-1 antibodies nivolumab and pembrolizumab are active in metastatic melanoma; however, there is limited data on combining anti-PD-1 antibody and…”
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FDG-PET to predict long-term outcome from anti-PD-1 therapy in metastatic melanoma
Published in Annals of oncology (01-01-2022)“…We have previously shown that 75% of patients treated with programmed cell death protein 1 (PD-1) with or without CTLA4 who have not progressed by 1 year have…”
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Single-agent anti-PD-1 or combined with ipilimumab in patients with mucosal melanoma: an international, retrospective, cohort study
Published in Annals of oncology (01-09-2022)“…BACKGROUNDMucosal melanoma (MM) is a rare melanoma subtype with distinct biology and poor prognosis. Data on the efficacy of immune checkpoint inhibitors…”
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Quantitative analysis and virulence phenotypes of atypical enteropathogenic Escherichia coli (EPEC) acquired from diarrheal stool samples from a Midwest US hospital
Published in Gut microbes (09-11-2020)“…Infectious diarrhea causes approximately 179 million illnesses annually in the US. Multiplex PCR assays for enteric pathogens detect enteropathogenic…”
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Antitumor activity of ipilimumab or BRAF ± MEK inhibition after pembrolizumab treatment in patients with advanced melanoma: analysis from KEYNOTE-006
Published in Annals of oncology (01-02-2022)“…Antitumor activity of ipilimumab or BRAF ± MEK inhibitors (BRAFi ± MEKi) following pembrolizumab administration in melanoma is poorly characterized. In the…”
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Is chemotherapy still an option in the treatment of melanoma?
Published in Annals of oncology (01-11-2015)Get full text
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