Search Results - "Carlin, Kevin P."
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Marine mammals harbor unique microbiotas shaped by and yet distinct from the sea
Published in Nature communications (03-02-2016)“…Marine mammals play crucial ecological roles in the oceans, but little is known about their microbiotas. Here we study the bacterial communities in 337 samples…”
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Studies Examining the Relationship between the Chemical Structure of Protoxin II and Its Activity on Voltage Gated Sodium Channels
Published in Journal of medicinal chemistry (14-08-2014)“…The aqueous solution structure of protoxin II (ProTx II) indicated that the toxin comprises a well-defined inhibitor cystine knot (ICK) backbone region and a…”
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3
Electrophysiological and Pharmacological Properties of Locomotor Activity-Related Neurons in cfos-EGFP Mice
Published in Journal of neurophysiology (01-12-2009)“…1 Department of Physiology; University of Manitoba, Winnipeg, Manitoba, Canada; 2 Departments of Anatomy and Neurobiology and 3 Surgery (Neurosurgery),…”
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Nitric oxide in the breath of bottlenose dolphins: Effects of breath hold duration, feeding, and lung disease
Published in Marine mammal science (01-01-2014)“…Breath analysis, including measurement of nitric oxide (NO), is a noninvasive diagnostic tool that may help evaluate cetacean health. This is the first report…”
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An in vitro functionally mature mouse spinal cord preparation for the study of spinal motor networks
Published in Brain research (23-01-1999)“…An in vitro isolated whole spinal cord preparation has been developed in `motor functionally mature' mice; that is mice of developmental maturity sufficient to…”
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Ratiometric Measurements of Adiponectin by Mass Spectrometry in Bottlenose Dolphins (Tursiops truncatus) with Iron Overload Reveal an Association with Insulin Resistance and Glucagon
Published in Frontiers in endocrinology (Lausanne) (2013)“…High molecular weight (HMW) adiponectin levels are reduced in humans with type 2 diabetes and insulin resistance. Similar to humans with insulin resistance,…”
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Serum profiling by MALDI-TOF mass spectrometry as a diagnostic tool for domoic acid toxicosis in California sea lions
Published in Proteome science (19-03-2012)“…There are currently no reliable markers of acute domoic acid toxicosis (DAT) for California sea lions. We investigated whether patterns of serum peptides could…”
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Comparison of Dolphins' Body and Brain Measurements with Four Other Groups of Cetaceans Reveals Great Diversity
Published in Brain, behavior and evolution (01-01-2016)“…We compared mature dolphins with 4 other groupings of mature cetaceans. With a large data set, we found great brain diversity among 5 different taxonomic…”
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Delphinid brain development from neonate to adulthood with comparisons to other cetaceans and artiodactyls
Published in Marine mammal science (01-04-2018)“…Why do neonatal and adult delphinids have much larger brains than artiodactyls when they have common ancestors? We explore relationships between neonatal brain…”
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Pregnancy profiles in the common bottlenose dolphin (Tursiops truncatus): Clinical biochemical and hematological variations during healthy gestation and a successful outcome
Published in Theriogenology (15-01-2020)“…The physiological demands of pregnancy inevitably result in changes of both biochemical and hematological parameters as the fetus develops. Alterations in…”
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Modulation of voltage-gated sodium channels hyperpolarizes the voltage threshold for activation in spinal motoneurones
Published in Experimental brain research (01-03-2012)“…Previous work has shown that motoneurone excitability is enhanced by a hyperpolarization of the membrane potential at which an action potential is initiated (…”
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Phenylarsine oxide as a redox modulator of transient receptor potential vanilloid type 1 channel function
Published in Journal of neuroscience research (01-02-2015)“…Transient receptor potential vanilloid type 1 (TRPV1) channels are capable of detecting and integrating noxious stimuli and play an important role in…”
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Staircase Currents in Motoneurons: Insight into the Spatial Arrangement of Calcium Channels in the Dendritic Tree
Published in The Journal of neuroscience (22-04-2009)“…In spinal motoneurons, activation of dendritically located depolarizing conductances can lead to amplification of synaptic inputs and the production of plateau…”
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ESTABLISHING MARGINAL LYMPH NODE ULTRASONOGRAPHIC CHARACTERISTICS IN HEALTHY BOTTLENOSE DOLPHINS (TURSIOPS TRUNCATUS)
Published in Journal of zoo and wildlife medicine (01-12-2017)“…Pulmonary disease has been well documented in wild and managed dolphin populations. The marginal lymph nodes of the dolphin thorax provide lymphatic drainage…”
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Cysteine racemization during the Fmoc solid phase peptide synthesis of the Nav1.7-selective peptide - protoxin II
Published in Journal of peptide science (01-07-2012)“…Protoxin II is biologically active peptide containing the inhibitory cystine knot motif. A synthetic version of the toxin was generated with standard Fmoc…”
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Iron Indices in Bottlenose Dolphins (Tursiops truncatus)
Published in Comparative medicine (01-12-2012)“…Bottlenose dolphins can have iron overload (that is, hemochromatosis), and managed populations of dolphins may be more susceptible to this disease than are…”
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Modulation of calcium currents in mouse ventral horn neurons by extracellular pH
Published in The European journal of neuroscience (01-11-2005)“…Neuronal activity has been shown to modulate the pH of the extracellular environment. Since neuronal circuits in the ventral horn of the spinal cord are highly…”
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Associations of ceruloplasmin and haptoglobin with inflammation and glucose in bottlenose dolphins (Tursiops truncatus)
Published in Comparative clinical pathology (01-07-2014)“…Bottlenose dolphins ( Tursiops truncatus ) have a diabetes-like metabolism and are susceptible to conditions, including chronic inflammation, hyperglycemia,…”
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Simulation techniques for localising and identifying the kinetics of calcium channels in dendritic neurones
Published in Neurocomputing (Amsterdam) (01-06-2000)“…The present simulations were designed to determine whether the current–voltage ( I– V) relationship obtained during voltage clamp was sufficient to…”
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SHORT COMMUNICATION: Modulation of calcium currents in mouse ventral horn neurons by extracellular pH
Published in The European journal of neuroscience (01-11-2005)“…Neuronal activity has been shown to modulate the pH of the extracellular environment. Since neuronal circuits in the ventral horn of the spinal cord are highly…”
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