Search Results - "Carlijn Vc, Bouten"
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Transiently heritable fates and quorum sensing drive early IFN-I response dynamics
Published in eLife (11-01-2023)“…Type I interferon (IFN-I)-mediated antiviral responses are central to host defense against viral infections. Crucial is the tight and well-orchestrated control…”
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Combining tissue repair and tissue engineering; bioactivating implantable cell-free vascular scaffolds
Published in Heart (British Cardiac Society) (01-12-2014)“…Synthetic replacement grafts for heart valves and small-diameter blood vessels such as coronary arteries have the potential to circumvent many of the…”
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3
Engineering tissue morphogenesis: taking it up a Notch
Published in Trends in biotechnology (Regular ed.) (01-08-2022)“…Recreating functional tissues through bioengineering strategies requires steering of complex cell fate decisions. Notch, a juxtacrine signaling pathway,…”
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4
Early in-situ cellularization of a supramolecular vascular graft is modified by synthetic stromal cell-derived factor-1α derived peptides
Published in Biomaterials (01-01-2016)“…Abstract In an in-situ approach towards tissue engineered cardiovascular replacement grafts, cell-free scaffolds are implanted that engage in endogenous tissue…”
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5
Changes in extracellular matrix in failing human non-ischemic and ischemic hearts with mechanical unloading
Published in Journal of molecular and cellular cardiology (01-05-2022)“…Ischemic and non-ischemic cardiomyopathies have distinct etiologies and underlying disease mechanisms, which require in-depth investigation for improved…”
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6
In Situ Tissue Engineering of Functional Small-Diameter Blood Vessels by Host Circulating Cells Only
Published in Tissue engineering. Part A (01-10-2015)“…Inflammation is a natural phase of the wound healing response, which can be harnessed for the in situ tissue engineering of small-diameter blood vessels using…”
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7
Development of Non-Cell Adhesive Vascular Grafts Using Supramolecular Building Blocks
Published in Macromolecular bioscience (01-03-2016)“…Cell‐free approaches to in situ tissue engineering require materials that are mechanically stable and are able to control cell‐adhesive behavior upon…”
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8
Tailoring fiber diameter in electrospun poly(epsilon-caprolactone) scaffolds for optimal cellular infiltration in cardiovascular tissue engineering
Published in Tissue engineering. Part A (01-02-2009)“…Despite the attractive features of nanofibrous scaffolds for cell attachment in tissue-engineering (TE) applications, impeded cell ingrowth has been reported…”
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Differential Response of Endothelial and Endothelial Colony Forming Cells on Electrospun Scaffolds with Distinct Microfiber Diameters
Published in Biomacromolecules (10-03-2014)“…Electrospun scaffolds for in situ tissue engineering can be prepared with different fiber diameters to influence cell recruitment, adhesion, and…”
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10
The Effects of Scaffold Remnants in Decellularized Tissue-Engineered Cardiovascular Constructs on the Recruitment of Blood Cells
Published in Tissue engineering. Part A (01-10-2017)“…Decellularized tissue-engineered heart valves (DTEHVs) showed remarkable results in translational animal models, leading to recellularization within hours…”
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In Vivo Collagen Remodeling in the Vascular Wall of Decellularized Stented Tissue-Engineered Heart Valves
Published in Tissue engineering. Part A (01-08-2015)“…Decellularized tissue-engineered heart valves (TEHVs) are under investigation as alternative for current heart valve prostheses with the potential to rapidly…”
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12
Strain-induced Collagen Organization at the Micro-level in Fibrin-based Engineered Tissue Constructs
Published in Annals of biomedical engineering (01-04-2013)“…Full understanding of strain-induced collagen organization in complex tissue geometries to create tissues with predefined collagen architecture has not been…”
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13
Computational model predicts cell orientation in response to a range of mechanical stimuli
Published in Biomechanics and modeling in mechanobiology (2014)“…To build anisotropic, mechanically functioning tissue, it is essential to understand how cells orient in response to mechanical stimuli. Therefore, a…”
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14
Heading in the Right Direction: Understanding Cellular Orientation Responses to Complex Biophysical Environments
Published in Cellular and molecular bioengineering (01-03-2016)“…The aim of cardiovascular regeneration is to mimic the biological and mechanical functioning of tissues. For this it is crucial to recapitulate the in vivo…”
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15
Decreased mechanical stiffness in LMNA−/− cells is caused by defective nucleo-cytoskeletal integrity: implications for the development of laminopathies
Published in Human molecular genetics (01-11-2004)“…Laminopathies comprise a group of inherited diseases with variable clinical phenotypes, caused by mutations in the lamin A/C gene (LMNA). A prominent feature…”
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16
Fluorescently labeled collagen binding proteins allow specific visualization of collagen in tissues and live cell culture
Published in Analytical biochemistry (15-03-2006)“…Visualization of the formation and orientation of collagen fibers in tissue engineering experiments is crucial for understanding the factors that determine the…”
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Superior Tissue Evolution in Slow-Degrading Scaffolds for Valvular Tissue Engineering
Published in Tissue engineering. Part A (01-01-2016)“…Synthetic polymers are widely used to fabricate porous scaffolds for the regeneration of cardiovascular tissues. To ensure mechanical integrity, a balance…”
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18
The relative contributions of compression and hypoxia to development of muscle tissue damage: an in vitro study
Published in Annals of biomedical engineering (01-02-2007)“…Deep pressure ulcers develop in tissues subjected to sustained mechanical loading. Though it has been hypothesized that this damage mechanism results from…”
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19
Tissue engineering of heart valves: advances and current challenges
Published in Expert review of medical devices (01-05-2009)“…It is estimated that the number of patients requiring heart valve replacement will triple over the next five decades. None of the current replacement valves…”
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Autologous human tissue-engineered heart valves : Prospects for systemic application
Published in Circulation (New York, N.Y.) (04-07-2006)“…Tissue engineering represents a promising approach for the development of living heart valve replacements. In vivo animal studies of tissue-engineered…”
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